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ClinicalTrials.gov public records Last synced Nov 12, 2026, 2:07 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 692 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Tooth Diseases Clear all

Conditions: Charcot-Marie-Tooth Disease, Type IA
Interventions: PXT3003; Drug
Lead sponsor: Pharnext S.C.A.; Other
Eligibility: 17 Years to 67 Years
Enrollment: 187 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 9
States / cities: Los Angeles, California • Gainesville, Florida • Kansas City, Kansas + 6 more

Conditions: Dental Caries
Interventions: Silver Diamine Fluoride (38%), Glass Ionomer Sealant, Fluoride Varnishes, Hygiene Intervention; Device · Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 5 Years to 13 Years
Enrollment: 1,200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Glenwood Springs, Colorado

Conditions: Dentinal Hypersensitivity, Dental Pain
Interventions: Potassium Nitrate, Placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Impacted Third Molar Tooth, Temporomandibular Disorder
Interventions: The Restful Jaw Device; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years to 30 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 4
States / cities: Burnsville, Minnesota • Eden Prairie, Minnesota • Minneapolis, Minnesota + 1 more

Conditions: Tooth Whitening, Tooth Discoloration
Interventions: Vitamin C toothpaste, Matching placebo; Drug
Lead sponsor: Colgate Palmolive; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: Melbourne, Florida

Conditions: Dental Caries
Interventions: Not listed
Lead sponsor: University of Michigan; Other
Eligibility: 9 Months to 15 Months
Enrollment: 1,326 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2017
U.S. locations: 3
States / cities: Indianapolis, Indiana • Iowa City, Iowa • Durham, North Carolina

Conditions: Dental Caries
Interventions: A "simple medical strategy" consisting of silver diamine fluoride (SDF), B "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride varnish (FV); Device
Lead sponsor: Case Western Reserve University; Other
Eligibility: 62 Years and older
Enrollment: 568 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Dentin Sensitivity
Interventions: Calcium sodium phosphosilicate (CSPS) Toothpaste; Other
Lead sponsor: HALEON; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Teeth Staining
Interventions: Toothpaste; Other
Lead sponsor: Boka LLC; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Fort Wayne, Indiana

Conditions: Persistent Post-concussive Syndrome, Concussion Post Syndrome
Interventions: Hyperbaric oxygen at 1.5 ATA, Sham treatment; Drug
Lead sponsor: Essentia Health; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Fargo, North Dakota

Conditions: Tooth Loss
Interventions: T3 Pro dental implant system; Device
Lead sponsor: ZimVie; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2028
U.S. locations: 2
States / cities: New Orleans, Louisiana • Minneapolis, Minnesota

Conditions: Dental Caries
Interventions: Xylitol gummy bears, Sugar free fiber gummy bears, Oral health education, Fluoride varnish, Dental sealant; Dietary Supplement · Behavioral · Device
Lead sponsor: Case Western Reserve University; Other
Eligibility: 5 Years to 6 Years
Enrollment: 562 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Dental Crowding, Dental Occlusion, Traumatic, Endodontic Disease, Orthodontic Treatment, Endodontic Lesions, PeriodontalConditions, Oral Surgery Conditions, Tooth Extractions, Local Anesthesia, Traumatic Dental Pain, TMJ, Orthodontics, Endodontic Histopathology, Periodontal Diseases
Interventions: dental-dedicated MRI (ddMRI); Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Dental Caries
Interventions: Fluoride Varnish, Glass Ionomer Sealant; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 2 Years to 3 Years
Enrollment: 597 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: San Ysidro, California

Conditions: Tooth Loss, Dental Implant, Clinical Trials, Randomized Controlled Trial, Immediate Dental Implant Placement, Molar Extraction Socket, Maxilla, MANDIBLE
Interventions: scannable anatomical healing abutment, Standard Healing Abutment for Dental Implants; Device
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 20 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 2
States / cities: Chicago, Illinois • Indianapolis, Indiana

Conditions: Pain
Interventions: Acetaminophen/naproxen sodium Dose A, Acetaminophen/naproxen sodium Dose B, Acetaminophen/naproxen sodium Dose C, Acetaminophen/naproxen sodium Dose D, Acetaminophen/naproxen sodium Dose E, Placebo; Drug
Lead sponsor: Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division; Industry
Eligibility: 17 Years to 50 Years
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Jaw, Edentulous, Partially
Interventions: immediate implant placement without provisionalization, immediate implant placement with immediate provisionalization; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 79 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Dental Caries of Root Surface, Surgery
Interventions: Making impression at surgery; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2021
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Psychotic Disorders
Interventions: Aripiprazole or Perphenazine, Metformin, Olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone, paliperidone, or olanzapine/fluoxetine; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 8 Years to 19 Years
Enrollment: 127 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2014
U.S. locations: 4
States / cities: Baltimore, Maryland • Glen Oaks, New York • Chapel Hill, North Carolina

Conditions: Dental Caries
Interventions: Restoration of dental caries with dental composite; Procedure
Lead sponsor: Carelon Research; Other
Eligibility: 3 Years to 17 Years
Enrollment: 113 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Watertown, Massachusetts

Conditions: Dental Caries
Interventions: C16G2; Drug
Lead sponsor: Armata Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2015
U.S. locations: 2
States / cities: Kalispell, Montana • Salt Lake City, Utah

Conditions: Dental Caries
Interventions: Not listed
Lead sponsor: Dental Practice-Based Research Network; Network
Eligibility: 6 Years and older
Enrollment: 2,624 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 6
States / cities: Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more

Conditions: Dentin Sensitivity
Interventions: Placebo, 15% nano-HAP toothpaste, 5% KNO3 toothpaste; Other · Device
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 20 Years to 80 Years
Enrollment: 192 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Prediabetic State, Type 2 Diabetes Mellitus With Oral Complications, Periodontal Pocket, Tooth Loss
Interventions: Enhanced intervention; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 30 Years and older
Enrollment: 101 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: New York, New York

Search by objective public record fields.

Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A

Building Adaptive School-based Interventions for Caries

The Effects of Potassium Nitrate in Reducing Dentinal Hypersensitivity

Assessing a New Jaw Support Device During Third Molar Extractions

Clinical Research Study to Evaluate Stain Removal and Whitening Improvement

Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings

Older Adult Effectiveness of 2 Treatments

Real-World Study of a Calcium Sodium Phosphosilicate Anti-Sensitivity Toothpaste for Dentin Hypersensitivity Relief

The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Sensitive Whitening Toothpaste, Containing 5% KNO3 (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains Over 4 Weeks of Unsupervised Use.

Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms

An Observational Study of the T3 Pro Dental Implant System

Xylitol for Caries Prevention in Inner-City Children

Exploration of the Utility of Dental-dedicated MRI for Dentistry

Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries

Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing Abutment

Acetaminophen/Naproxen Sodium Dose Ranging Study

The Effect of Immediate Implant Placement and Provisionalization in the Esthetic Zone

Intraoral Imaging at Clinical Crown Lengthening

Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics

Composites and Urinary Bisphenol-A Study

Phase 2, Open-Label Study for Safety, Microbiology and PK of Single or Multiple Oral C16G2 Gel Doses

DPBRN Prevalence of Questionable Occlusal Caries Lesions

Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity

Undiagnosed Diabetes in a Dental Setting