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ClinicalTrials.gov public records Last synced Oct 23, 2026, 4:18 AM EDT

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Showing 97–120 of 139 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tooth Extractions Clear all
Recruiting Not applicable Interventional

Comparison of Two Types of Bone Grafts in Patients Who Need One of Their Front Teeth Removed and Replaced With an Implant

NCT06722482
View directory record Official record
Conditions
Ridge Preservation, Allografts, Extraction, Tooth, Xenograft
Interventions
FDBA, CEBX
Device
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Oct 23, 2026, 4:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery

NCT07731295
View directory record Official record
Conditions
Pain, Postoperative, Substance Use
Interventions
iPAWS, Educational Materials
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
15 Years to 20 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Porcine Membrane vs Bovine Wound Dressing in Human Tooth Extraction Sites

NCT05802602
View directory record Official record
Conditions
Wound Heal
Interventions
Porcine Collagen Membrane, Bovine Collagen Dressing
Device
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 23, 2026, 4:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

NCT07095556
View directory record Official record
Conditions
Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management, Tooth Extraction Site Healing
Interventions
Low-level laser therapy
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 23, 2026, 4:18 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Ultrasound-based Imaging to Detect Early Changes of Hard and Soft Tissue Around Immediately Placed Implants With or Without Soft Tissue Augmentation

NCT05330702
View directory record Official record
Conditions
Tooth Extraction, Immediate Implant Placement
Interventions
Xenogeneic Volume-Stable Collagen Matrix (VCMX) graft No Intervention: No Soft Tissue Augmentation, Tuberosity Connective Tissue Graft (CTG)
Device · Procedure
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 95 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Trial to Test the Effect of a Marketed Mouth Rinse on Stain Removal

NCT02151058
View directory record Official record
Conditions
Tooth Stain
Interventions
Colgate® Regular Cavity Protection, Experimental Mouth Rinse, Crest® 3D White Multi-Care Whitening Rinse, Glamorous White, Fresh Mint
Drug · Other
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
18 Years to 65 Years
Enrollment
227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Clinical Research Study to Evaluate Stain Removal and Whitening Improvement

NCT07870018
View directory record Official record
Conditions
Tooth Whitening, Tooth Discoloration
Interventions
Vitamin C toothpaste, Matching placebo
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®

NCT03659617
View directory record Official record
Conditions
Tooth Loss
Interventions
xenograft (BioOss Collagen)
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 95 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Evaluation of OSSIX-Plus Resorbable Collagen Membranes for Alveolar Ridge Preservation Following Exodontia

NCT00639860
View directory record Official record
Conditions
Alveolar Bone Loss, Loss of Teeth Due to Extraction, Edentulous Alveolar Ridge
Interventions
OSSIX-Plus
Device
Lead sponsor
William Giannobile
Other
Eligibility
18 Years to 80 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 31, 2016 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 2 Interventional

Capsaicin to Control Pain Following Third Molar Extraction

NCT00088686
View directory record Official record
Conditions
Healthy, Tooth Extraction
Interventions
Capsaicin (Intramucosal Injection)
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Treatment of Alveolar Bone Defects Using Aastrom Biosciences Autologous Tissue Repair Cell Therapy

NCT00755911
View directory record Official record
Conditions
Alveolar Bone Loss
Interventions
Tissue Repair Cells (TRC), Control
Biological · Device
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 3, 2015 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 2 Interventional

Study of Acetaminophen (ACE) in Post-operative Dental Pain

NCT02320708
View directory record Official record
Conditions
Dental Pain
Interventions
Acetaminophen (ACE) (1000 mg), Commercial ACE (1000 mg), Commercial Ibuprofen (IBU) (400 mg), Placebo
Drug
Lead sponsor
Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.
Industry
Eligibility
17 Years to 50 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 3, 2021 · Synced Oct 23, 2026, 4:18 AM EDT
Not yet recruiting Phase 2 Interventional

Jaw Muscle Pain Post Wisdom Molar Surgery

NCT07094542
View directory record Official record
Conditions
Post Operative Pain, Impacted Third Molar Tooth, Muscle Pain
Interventions
Temporo-masseteric Nerve Block Injection, Oral Pain Medications only
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Temporary Anchorage Devices for Ridge Preservation

NCT03205800
View directory record Official record
Conditions
Ridge Preservation
Interventions
Mini-screw
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 2 Interventional

Rofecoxib to Prevent Pain After Third Molar (Wisdom Tooth) Extraction

NCT00026819
View directory record Official record
Conditions
Pain
Interventions
Rofecoxib
Drug
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Not applicable Interventional Results available

Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft

NCT01588444
View directory record Official record
Conditions
Tooth Extraction
Interventions
cortical FDBA, Cancellous FDBA
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
19 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 22, 2015 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Dental Pain Study of Analgesics in Patients Undergoing Molar Removal

NCT03652818
View directory record Official record
Conditions
Dental Pain
Interventions
Pre-Op pregabalin, Pre-Op Placebo 1, Post-Op pregabalin, Post-Op Placebo 1, Post-Op Placebo 2, Post-Op acetaminophen
Drug
Lead sponsor
Nevakar, Inc.
Industry
Eligibility
17 Years to 55 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites

NCT01244997
View directory record Official record
Conditions
Dental Caries
Interventions
Dental Implant
Procedure
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
21 Months to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 22, 2010 · Synced Oct 23, 2026, 4:18 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft

NCT04550689
View directory record Official record
Conditions
Tooth Loss
Interventions
Bone graft
Device
Lead sponsor
UConn Health
Other
Eligibility
21 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 3 Interventional Results available

A Safety And Efficacy Study of Ibuprofen 250 mg / Acetaminophen 500 mg In The Treatment Of Post-Surgical Dental Pain

NCT02912650
View directory record Official record
Conditions
Post-surgical Pain Following Extraction of Molar Teeth
Interventions
Ibuprofen 250 mg / Acetaminophen 500 mg, Ibuprofen 250 mg, Acetaminophen 650 mg, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 40 Years
Enrollment
568 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 30, 2017 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Not applicable Interventional

Extrinsic Tooth Whitening Evaluation of a Whitening Toothpaste

NCT07428603
View directory record Official record
Conditions
Stain Removal Efficacy
Interventions
Whitening Test Dentifrice (Code 826), Control dentifrice (Code 378)
Other
Lead sponsor
Church & Dwight Company, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 23, 2026, 4:18 AM EDT
Completed Phase 2 Interventional

A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction

NCT00663767
View directory record Official record
Conditions
Dental Pain
Interventions
Placebo; oral, ARRY-371797, p38 inhibitor; oral, Celecoxib, COX-2 inhibitor; oral
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 65 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
2
States / cities
Austin, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Oct 23, 2026, 4:18 AM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers

Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites

NCT00067392
View directory record Official record
Conditions
Dental Caries
Interventions
Dental Implant
Procedure
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
21 Months to 65 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 9, 2010 · Synced Oct 23, 2026, 4:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Feasibility Testing of a New Way to Support the Jaw During 3rd Molar Extractions

NCT03512769
View directory record Official record
Conditions
Impacted Third Molar Tooth, Temporomandibular Joint Dysfunction Syndrome
Interventions
Restful Jaw Device
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 24 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Oct 23, 2026, 4:18 AM EDT