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ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:13 PM EDT

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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Tooth Movement Clear all
Completed Not applicable Interventional Results available

Accelerated Invisalign Therapy in Conjunction With Acceledent Aura

NCT02868554
View directory record Official record
Conditions
Malocclusion
Interventions
AcceleDent Aura, Accelerated Invisalign therapy
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 17, 2026, 9:13 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment

NCT02954133
View directory record Official record
Conditions
Malocclusion
Interventions
Invisalign (7 day), Invisalign (5 day), OrthoPulse, Invisalign (3.5 day)
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
4
States / cities
Chandler, Arizona • Maple Grove, Minnesota • Henderson, Nevada + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Results available

Alveolar Microperforation for Inflammation-Enhanced Tooth Movement During Orthodontic Treatment

NCT01720797
View directory record Official record
Conditions
Malocclusion
Interventions
Micro-osteoperforation, Anesthestic, Chlorhexidine
Device · Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 19, 2015 · Synced Oct 17, 2026, 9:13 PM EDT
Completed No phase listed Observational

Project AWARE 2.0 to Improve Awareness, Willingness and Ability for Research and Enrollment in Clinical Research

NCT06343220
View directory record Official record
Conditions
Huntington Disease
Interventions
Not listed
Lead sponsor
Huntington Study Group
Network
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 17, 2026, 9:13 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Effect of Tooth Position During Orthodontic Treatment on the Apnea/ Hypopnea Index (AHI)

NCT03299023
View directory record Official record
Conditions
Obstructive Sleep Apnea, Orthodontic Tooth Movement, Apnea, Sleep Disordered Breathing
Interventions
Medibyte Portable Monitor
Other
Lead sponsor
Harvard School of Dental Medicine
Other
Eligibility
8 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Results available

The Effect of OrthoPulse™ on the Rate of Orthodontic Tooth Movement

NCT02267811
View directory record Official record
Conditions
Malocclusion
Interventions
Orthodontic Treatment, OrthoPulse™
Other · Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners

NCT01962012
View directory record Official record
Conditions
Malocclusion
Interventions
AcceleDent Aura, Sham Device
Device
Lead sponsor
OrthoAccel Technologies Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2016 · Synced Oct 17, 2026, 9:13 PM EDT
Enrolling by invitation Phase 1Phase 2 Interventional

Lithium for Parkinson's: an Extension Trial

NCT06592014
View directory record Official record
Conditions
Parkinson Disease
Interventions
Lithium aspartate
Dietary Supplement
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
45 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Characterizing Orthodontic Tooth Movement With Photographic Scans

NCT05780788
View directory record Official record
Conditions
Canine Retraction
Interventions
Monitoring Tooth Movement
Device
Lead sponsor
UConn Health
Other
Eligibility
11 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Analysis of Orthodontic Tooth Movement Using 3D Imaging

NCT03398798
View directory record Official record
Conditions
Tooth Crowding, Dental Crowding, Malocclusion
Interventions
.014", .016", Twin brackets, Self-ligating brackets
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
10 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Huntersville, North Carolina
Source: ClinicalTrials.gov public record
Updated May 1, 2020 · Synced Oct 17, 2026, 9:13 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Study of the Use of Orthopulse Photobiomodulation

NCT05650359
View directory record Official record
Conditions
Orthodontics
Interventions
OrthoPulse, No intervention
Device · Other
Lead sponsor
Biolux Technology GmbH
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Chandler, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 7, 2024 · Synced Oct 17, 2026, 9:13 PM EDT
Recruiting Not applicable Interventional

A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.

NCT07290790
View directory record Official record
Conditions
Malocclusion
Interventions
SureSmile® Clear Aligners
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
4
States / cities
Fresno, California • Princeton Junction, New Jersey • Huntersville, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 17, 2026, 9:13 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Effect of OrthoPulse Photobiomodulation on the Rate of Tooth Movement During Alignment With Fixed Appliances

NCT03202355
View directory record Official record
Conditions
Malocclusion
Interventions
Fixed Appliance Orthodontic Treatment, OrthoPulse™
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 8, 2019 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Biomarkers of Orthodontic Tooth Movement With Fixed Appliances and Vibration Appliance Therapy

NCT02119455
View directory record Official record
Conditions
Tooth Movement
Interventions
Vibration Device
Device
Lead sponsor
UConn Health
Other
Eligibility
15 Years to 35 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 13, 2019 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Results available

Accelerated Tooth Movement With AcceleDent® and Aligners - a Pilot Project

NCT02438280
View directory record Official record
Conditions
Tooth Movement, Malocclusion
Interventions
AcceleDent, Vibrational Device
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 30, 2018 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of the Efficacy of the Aerodentis System

NCT03421886
View directory record Official record
Conditions
Orthodontic Treatment, Tooth Crowding, Orthodontics
Interventions
Aerodentis system, Invisalign clear aligner system
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial to Assess the Efficacy of Reducing the Aligners' Wear Protocol

NCT05905224
View directory record Official record
Conditions
Orthodontic Tooth Movement
Interventions
Invisalign 7-day wear protocol, Invisalign 3-day wear protocol
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 30 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 17, 2026, 9:13 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Gingival Crevicular Fluid Characterization During Orthodontic Treatment

NCT04226469
View directory record Official record
Conditions
Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
Interventions
Tooth movement
Procedure
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
11 Years to 35 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Use of Clear Aligners With Movement Enhancement Techniques

NCT02087163
View directory record Official record
Conditions
Malocclusion
Interventions
Movement Enhancement Technique, Clear Aligner
Device
Lead sponsor
Align Technology, Inc.
Industry
Eligibility
16 Years to 46 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 17, 2026, 9:13 PM EDT
Completed Phase 3 Interventional Results available

Effect of Cyclic Loading (Vibration) on Orthodontic Tooth Movement

NCT00830947
View directory record Official record
Conditions
Malocclusion
Interventions
OrthoAccel Device, Sham Device
Device
Lead sponsor
OrthoAccel Technologies Inc.
Industry
Eligibility
12 Years to 40 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 23, 2013 · Synced Oct 17, 2026, 9:13 PM EDT