Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jul 23, 2026, 11:47 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 36 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Toothbrush Clear all
Completed No phase listed Observational Accepts healthy volunteers

A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health

NCT05594004
View directory record Official record
Conditions
Gingivitis, Dental Plaque
Interventions
Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,929 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 25, 2022 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Powered Toothbrush Versus Manual Toothbrush on Plaque and Gingivitis After a Six-Week Period of Home Use

NCT07691814
View directory record Official record
Conditions
Gingivitis
Interventions
power toothbrush, manual toothbrush
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 65 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Full-mouth Electronic Toothbrush vs. Conventional Electronic Toothbrush

NCT06561204
View directory record Official record
Conditions
Toothbrush, Gingivitis, Plaque
Interventions
FMET
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Study to Determine the Safety and Effectiveness of Dentinal Hypersensitivity Treatment With Two Different Toothbrushes

NCT02513212
View directory record Official record
Conditions
Dentin Sensitivity
Interventions
Potassium Oxalate, Stannous fluoride paste, Manual toothbrush, Power toothbrush
Device · Drug
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2020 · Synced Jul 23, 2026, 11:47 PM EDT
Completed No phase listed Observational

Assessing the Colgate Assist Handle Toothbrush in Individuals With Impairment of Hand Movement.

NCT06632704
View directory record Official record
Conditions
Movement Disorders and Physical Impairments
Interventions
Colgate Toothbrush assist
Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2025 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

At-Home Care for Subjects With Periodontitis

NCT04254770
View directory record Official record
Conditions
Periodontitis, Dental Plaque
Interventions
ADA approved Manual Toothbrush, Marketed Power Toothbrush
Device
Lead sponsor
Philips Clinical & Medical Affairs Global
Industry
Eligibility
18 Years to 75 Years
Enrollment
346 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 24, 2022 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)

NCT02366689
View directory record Official record
Conditions
Dental Plaque, Gingivitis
Interventions
Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste, Cetylpyridinium chloride mouthwash, Fluoride only mouthwash
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Cedar Knolls, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 29, 2016 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Self-selection Study of the Toothwave Toothbrush

NCT04023097
View directory record Official record
Conditions
Gingivitis, Plaque, Calculus, Tooth Discoloration
Interventions
Toothwave toothbrush
Device
Lead sponsor
Home Skinovations Ltd.
Industry
Eligibility
18 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2020 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of the ToothWave Powered Toothbrush for Extrinsic Stain Reduction (Texas)

NCT04092062
View directory record Official record
Conditions
Tooth Discoloration
Interventions
ToothWave, powered toothbrush
Device
Lead sponsor
Home Skinovations Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 10, 2020 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of an Experimental Toothbrush for Treatment and Prevention of Gingivitis

NCT01224158
View directory record Official record
Conditions
Dental Devices, Home Care
Interventions
Experimental Power Toothbrush, Flat trimmed Manual Toothbrush
Device
Lead sponsor
Johnson & Johnson Consumer and Personal Products Worldwide
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Powertoothbrushing for Treating Gingivitis

NCT03381339
View directory record Official record
Conditions
Gingivitis
Interventions
Oscillating rotating power toothbrush
Device
Lead sponsor
Marquette University
Other
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 4, 2021 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Toothbrush Wear and Its Effect on Subgingival Inflammation Using Two Different Brushing Techniques

NCT03158350
View directory record Official record
Conditions
Gingival Inflammation
Interventions
Instructed Brushing Method
Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2019 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Plaque Removal Efficacy of a U-Shaped Sonic Power Toothbrush in Children

NCT06300073
View directory record Official record
Conditions
Dental Plaque
Interventions
Experimental: U-shaped Power Toothbrush, Placebo Comparator: Soft Manual Toothbrush
Device
Lead sponsor
Lander Enterprises, LLC
Industry
Eligibility
5 Years to 8 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 7, 2024 · Synced Jul 23, 2026, 11:47 PM EDT
Active, not recruiting Phase 3 Interventional Accepts healthy volunteers

To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis.

NCT07605338
View directory record Official record
Conditions
Plaque, Dental, Gingivitis
Interventions
Colgate SNaP Total 10/10, 1.5 Taurate, Colgate Great Regular Flavor Toothpaste, Flat Trimmed Extra Clean TB
Drug · Other
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Costa Mesa, California
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Jul 23, 2026, 11:47 PM EDT
Completed No phase listed Observational

The Effects of Oscillating-Rotating Electric Toothbrushes on Plaque and Gingival Health

NCT04017507
View directory record Official record
Conditions
Gingivitis, Plaque
Interventions
Oscillating-rotating electric toothbrush, Side-to-side electric toothbrush, Manual toothbrush
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,145 participants
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.

NCT07398846
View directory record Official record
Conditions
Plaque
Interventions
0.454%Stannous fluoride toothpaste, 0.075% Cetylpyridinium Chloride (CPC) and 0.28% zinc lactatmouthwashe, 0.76% Sodium Monofluorophosphate (Na MFP) toothpaste, 0.022% Sodium Fluoride mouthwash
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.

NCT06244303
View directory record Official record
Conditions
Gingivitis, Plaque
Interventions
manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F), manual toothbrush + Colgate dental cream
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Costa Mesa, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Toothbrush Bristles in Plaque Reduction

NCT04681885
View directory record Official record
Conditions
Plaque, Dental, Gingivitis
Interventions
Tapered bristles A, Tapered bristles B, End rounded bristles
Device
Lead sponsor
Sunstar Americas
Industry
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Plaque Removal of a Novel Brushing Device

NCT05038293
View directory record Official record
Conditions
Dental Plaque
Interventions
Automated mouthpiece-based toothbrush, Manual toothbrush
Device
Lead sponsor
University of Washington
Other
Eligibility
5 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy and Safety Study of Interproximal Cleaning Modalities on Oral Health

NCT02187016
View directory record Official record
Conditions
Gingivitis
Interventions
AirFloss + BreathRx, AirFloss + Listerine, Dental Floss, Manual Toothbrush
Device
Lead sponsor
Philips Oral Healthcare
Industry
Eligibility
18 Years to 65 Years
Enrollment
290 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush

NCT04221334
View directory record Official record
Conditions
Gingivitis, Plaque, Dental
Interventions
Electric Toothbrush, oral health care application
Device · Other
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2020 · Synced Jul 23, 2026, 11:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery

NCT06122805
View directory record Official record
Conditions
Toothbrushing, Gingivitis, Cleft Lip and Palate
Interventions
Toothbrush
Device
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
6 Years to 20 Years
Enrollment
198 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 12, 2024 · Synced Jul 23, 2026, 11:47 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis.

NCT06565897
View directory record Official record
Conditions
Plaque, Dental, Gingivitis
Interventions
Test regimen, Control regimen
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 70 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Melbourne, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 23, 2026, 11:47 PM EDT
Completed No phase listed Observational

Children in the Operating Room: Kids That go Thru Operating Room Will be Given a Connected Health Toothbrush, Kids Anticavity Toothpaste and Behavioral Health Intervention to Reduce Claim Costs

NCT07539064
View directory record Official record
Conditions
Caries Active, Prevention
Interventions
Connected Toothbrush with a behavioral health intervention
Device
Lead sponsor
Colgate Palmolive
Industry
Eligibility
4 Years to 7 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lakewood, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 23, 2026, 11:47 PM EDT