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Showing 1–24 of 293 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Total Hip Replacement Clear all
Completed Not applicable Interventional

Local Anesthetic Infiltration and Infusion for Pain Control After Hip Replacement

NCT01409278
View directory record Official record
Conditions
Osteoarthritis
Interventions
Ropivacaine infiltration and saline infusion., Ropivacaine infiltration and infusion., Normal Saline
Procedure
Lead sponsor
Trinity Health Of New England
Other
Eligibility
18 Years to 80 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 3, 2011 · Synced Sep 3, 2026, 5:44 AM EDT
Recruiting No phase listed Observational

Polyethylene Wear Particle Analysis of THA

NCT06432543
View directory record Official record
Conditions
Wear of Articular Bearing Surface of Prosthetic Joint, Hip Arthropathy
Interventions
polyethylene
Device
Lead sponsor
Osaka Metropolitan University
Other
Eligibility
20 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2025 · Synced Sep 3, 2026, 5:44 AM EDT
Completed Not applicable Interventional

A Randomized Study of Approaches in Total Hip Arthroplasty

NCT01613508
View directory record Official record
Conditions
Total Hip Replacement
Interventions
Direct Anterior Approach, Mini-Posterior Approach
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
20 Years to 100 Years
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 4, 2018 · Synced Sep 3, 2026, 5:44 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Tranexamic Acid Study

NCT00375440
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip
Interventions
Tranexamic Acid
Drug
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Oct 4, 2015 · Synced Sep 3, 2026, 5:44 AM EDT
Completed Phase 3 Interventional

Durom(R) Hip Resurfacing System Multicenter Trial

NCT00746616
View directory record Official record
Conditions
Advanced Hip Disease
Interventions
Durom Hip Resurfacing System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
5
States / cities
Denver, Colorado • De Witt, New York • Tulsa, Oklahoma + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2013 · Synced Sep 3, 2026, 5:44 AM EDT
Completed Not applicable Interventional

Study of Two Surgical Approaches for Total Hip Arthroplasty

NCT00881998
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Minimally Invasive Total Hip Arthroplasty, Conventional Total Hip Arthroplasty
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2009 · Synced Sep 3, 2026, 5:44 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Analgesic Comparison of PENG/LFCN to FICB for Total Hip Arthroplasty

NCT05477641
View directory record Official record
Conditions
Analgesia
Interventions
Pericapsular Nerve Group Block with Lateral Femoral Cutaneous Nerve Block, Fascia Iliaca Compartment Block
Procedure
Lead sponsor
SSM Health Bone and Joint Hospital at St Anthony
Other
Eligibility
40 Years to 80 Years
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Sep 3, 2026, 5:44 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Sleep Patterns After Total Joint Replacement Surgery

NCT04896892
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 3, 2026, 5:44 AM EDT
Not listed Not applicable Interventional

KINCISE™ Surgical Automated System in Total Hip Arthroplasty (THA)

NCT05223777
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
KINCISE, Traditional Handheld Mallet
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Sep 3, 2026, 5:44 AM EDT
Terminated Not applicable Interventional Results available

Pelvic Alignment Level (PAL) Instrument Evaluation

NCT01312428
View directory record Official record
Conditions
Arthroplasty, Replacement, Hip
Interventions
Pelvic Alignment Level (PAL) Instrument, No Pelvic Alignment Level (PAL) Instrument
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 16, 2017 · Synced Sep 3, 2026, 5:44 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Stability of Revision Total Hip Arthroplasty Implants Using Radiostereometric Analysis

NCT01668160
View directory record Official record
Conditions
Osteoarthritis of Hip, Failure of Primary THA
Interventions
Bead placement during revision hip replacement surgery
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
25 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2013 · Synced Sep 3, 2026, 5:44 AM EDT
Withdrawn No phase listed Observational

Investigation of Systemic Metal Ion Concentration Following a Ceramic-on-metal Total Hip Arthroplasty

NCT00883805
View directory record Official record
Conditions
Hip Replacement, Hip Implant, Total Hip Arthroplasty, Orthopaedic Surgery
Interventions
Blood draw, X-Ray of Hip
Biological · Radiation
Lead sponsor
Northwell Health
Other
Eligibility
40 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2015 · Synced Sep 3, 2026, 5:44 AM EDT
Terminated Not applicable Interventional

Health Partner Evaluation at Princeton

NCT03386786
View directory record Official record
Conditions
Total Knee Arthroplasty; Total Hip Arthroplasty
Interventions
Health Partner, Standard Care
Behavioral
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
18 Years and older
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Plainsboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 1, 2020 · Synced Sep 3, 2026, 5:44 AM EDT
Active, not recruiting Not applicable Interventional

Patient Utilization of Opioid Destruction Bags in the Post-op Period

NCT05875857
View directory record Official record
Conditions
Opioid Use, Opioid Use, Unspecified, Patient Empowerment, Total Knee Arthoplasty, Total Hip Arthroplasty
Interventions
Opioid destruction education
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 100 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Sep 3, 2026, 5:44 AM EDT
Active, not recruiting No phase listed Observational

Long-term Outcomes of Complex Conversion Total Hip Arthroplasty

NCT06533020
View directory record Official record
Conditions
Arthroplasty Complications
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Sep 3, 2026, 5:44 AM EDT
Completed No phase listed Observational

Ceramic On Ceramic (COC) 36mm PAS IDE Rollover Subjects; Ceramic Acetabular Bearing With Ceramic Femoral Head in Total Hip Replacement

NCT02096198
View directory record Official record
Conditions
Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-Traumatic Osteoarthritis of Hip
Interventions
Not listed
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
20 Years to 75 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
5
States / cities
Sacramento, California • Denver, Colorado • Winston-Salem, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2019 · Synced Sep 3, 2026, 5:44 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Study Comparing Topical Versus Intravenous Tranexamic Acid in Anterior Total Hip Arthroplasty

NCT03359525
View directory record Official record
Conditions
Tranexamic Acid Adverse Reaction
Interventions
Tranexamic Acid
Drug
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 80 Years
Enrollment
114 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Dec 1, 2017 · Synced Sep 3, 2026, 5:44 AM EDT
Not yet recruiting Not applicable Interventional

Alexis Retractor in Total Hip Arthroplasty

NCT07237737
View directory record Official record
Conditions
Hip Osteoarthritis, Hip Arthritis
Interventions
Alexis wound retractor, Standard wound retractor
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 3, 2026, 5:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Correlation of Spinopelvic Parameters and Acetabular Cup Orientation

NCT02598700
View directory record Official record
Conditions
Hip Osteoarthritis, Complications; Arthroplasty
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 6, 2019 · Synced Sep 3, 2026, 5:44 AM EDT
Completed Not applicable Interventional Results available

Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin)

NCT00634907
View directory record Official record
Conditions
Venous Thromboembolism, Bleeding
Interventions
Pharmacogenetic-based warfarin dosing, Usual care warfarin dosing
Genetic · Other
Lead sponsor
Gwen McMillin
Other
Eligibility
18 Years and older
Enrollment
263 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 7, 2017 · Synced Sep 3, 2026, 5:44 AM EDT
Completed Not applicable Interventional Results available

A Trial Comparing Mini-posterior Approach and Direct Anterior Approach

NCT01024309
View directory record Official record
Conditions
Osteoarthritis
Interventions
Mini-Posterior surgical approach for total hip arthroplasty, Direct Anterior surgical approach for total hip arthroplasty
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
25 Years to 80 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2014 · Synced Sep 3, 2026, 5:44 AM EDT
Not listed Not applicable Interventional

Medium Term Survivorship of Cementless THA Performed Using the Bone Preservation Tri-Lock Femoral Stem

NCT01566916
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Total Hip Arthroplasty
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
2
States / cities
Egg Harbor, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2014 · Synced Sep 3, 2026, 5:44 AM EDT
Completed Phase 2 Interventional

Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip Arthroplasty

NCT00818493
View directory record Official record
Conditions
Postoperative Pain
Interventions
Q8003 (morphine sulfate and oxycodone hydrochloride), Low dose Q8003 (morphine sulfate and oxycodone hydrochloride), Percocet (oxycodone and acetaminophen)
Drug
Lead sponsor
QRxPharma Inc.
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
4
States / cities
Birmingham, Alabama • Phoenix, Arizona • Royal Oak, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated May 16, 2012 · Synced Sep 3, 2026, 5:44 AM EDT
Recruiting Phase 4 Interventional

The Pericapsular Nerve Block in Total Hip Arthroplasty

NCT04729686
View directory record Official record
Conditions
Hip Osteoarthritis, Hip Arthropathy
Interventions
Pericapsular Nerve Block, Fascia Iliaca Nerve Block
Drug
Lead sponsor
LifeBridge Health
Other
Eligibility
18 Years to 80 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 3, 2026, 5:44 AM EDT