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Showing 1–24 of 289 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Total Hip Replacement Arthroplasty Clear all
Completed Phase 3 Interventional

Regulation of Coagulation in Orthopedic Surgery to Prevent DVT and PE, a Controlled, Double-blind, Randomized Study of BAY 59-7939 in the Extended Prevention of VTE in Patients Undergoing Elective Total Hip Replacement

NCT00332020
View directory record Official record
Conditions
Prevention, Venous Thromboembolism
Interventions
Rivaroxaban (BAY59-7939), Enoxaparin
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
2,457 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
5
States / cities
Birmingham, Alabama • Denver, Colorado • Bay Pines, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2015 · Synced Sep 1, 2026, 9:19 PM EDT
Completed Not applicable Interventional Results available

A Prospective Study to Evaluate the Effectiveness of a Haemostatic Agent in Primary Unilateral Total Hip Arthroplasty

NCT01285024
View directory record Official record
Conditions
Arthritis
Interventions
Vitagel
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 1, 2026, 9:19 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement

NCT03119038
View directory record Official record
Conditions
Osteoarthritis, Degenerative Joint Disease
Interventions
Bupivicaine + epinephrine, Bupivacaine, Ropivacaine, Ketorolac, Clonidine Injection
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 26, 2022 · Synced Sep 1, 2026, 9:19 PM EDT
Completed Not applicable Interventional Results available

Correlation of Spinopelvic Movement With Lateral Radiographs

NCT05117229
View directory record Official record
Conditions
Spinopelvic Relationships as They Relate to Total Hip Arthroplasty's
Interventions
MetaWear Sensor
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 1, 2026, 9:19 PM EDT
Not listed Not applicable Interventional

Direct Anterior Versus Posterior Total Hip Arthroplasty Surgical Approaches

NCT01807494
View directory record Official record
Conditions
Osteoarthritis, Avascular Necrosis
Interventions
Total hip replacement components
Device
Lead sponsor
New Lexington Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2023
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 5, 2015 · Synced Sep 1, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Effects of tDCS Combined With CBI on Postsurgical Pain

NCT04199780
View directory record Official record
Conditions
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain)
Interventions
Transcranial Direct Current Stimulation, Cognitive-Behavioral (CB) intervention
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 1, 2026, 9:19 PM EDT
Not listed Not applicable Interventional

Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA

NCT00551967
View directory record Official record
Conditions
Osteoarthritis of Hip, Traumatic Arthritis of Hip
Interventions
Hip replacement
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2017 · Synced Sep 1, 2026, 9:19 PM EDT
Recruiting Not applicable Interventional

Binaural Beats for Postoperative Pain and Anxiety Reduction

NCT07437469
View directory record Official record
Conditions
TKA, THA, Anxiety, Binaural Beats, Music Exposure, Total Hip Arthroplasty (THA), Total Knee Arthroplasty, Total Knee Replacement, Total Hip Replacement
Interventions
Binaural Beats Audio Intervention, Music of Choice
Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 1, 2026, 9:19 PM EDT
Not listed No phase listed Observational

Retrospective Chart Analysis in the Effective Use of FloSeal in Post-Operative Joint Replacements

NCT00958945
View directory record Official record
Conditions
Total Knee Arthroplasty, Arthroplasty, Replacement, Hip
Interventions
Not listed
Lead sponsor
Desert Orthopedic Center Medical Research Foundation
Other
Eligibility
18 Years to 95 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Rancho Mirage, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2009 · Synced Sep 1, 2026, 9:19 PM EDT
Terminated Phase 2 Interventional Results available

Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip Replacement

NCT00621530
View directory record Official record
Conditions
Hip Arthroplasty
Interventions
ketorolac tromethamine opthalmic solution, placebo
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Sep 1, 2026, 9:19 PM EDT
Terminated Not applicable Interventional Results available

Improvement in Wound Healing With Negative Pressure Wound Therapy for Postoperative Total Hip Arthroplasty

NCT02355691
View directory record Official record
Conditions
Complications; Arthroplasty, Infection or Inflammation, Wound Complication
Interventions
PREVENA
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 16, 2018 · Synced Sep 1, 2026, 9:19 PM EDT
Completed Not applicable Interventional Results available

Deep Vein Thrombosis (DVT) Prevention in Total Hip Arthroplasty: Continuous Enhanced Circulation Therapy (CECT) Versus Low Molecular Weight Heparin (LMWH)

NCT00358735
View directory record Official record
Conditions
Deep Vein Thrombosis of Lower Limb, Pulmonary Embolism (PE), Bleeding
Interventions
ActiveCare CECT device, Enoxaparin
Device · Drug
Lead sponsor
Medical Compression Systems
Industry
Eligibility
18 Years and older
Enrollment
411 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
9
States / cities
La Jolla, California • Loma Linda, California • Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2014 · Synced Sep 1, 2026, 9:19 PM EDT
Completed No phase listed Observational

Cognition in Postoperative Total Hip Arthroplasty and Total Hip Resurfacing Patients

NCT01079468
View directory record Official record
Conditions
Cognition
Interventions
Not listed
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2011 · Synced Sep 1, 2026, 9:19 PM EDT
Completed Phase 4 Interventional

Metformin Use in Patients Undergoing Total Joint Replacement Surgery

NCT06280274
View directory record Official record
Conditions
Hyperglycemia
Interventions
Metformin, Placebo
Drug · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 1, 2026, 9:19 PM EDT
Withdrawn Phase 4 Interventional

Single Versus Multi-Dose Oral Tranexamic Acid in Patients at High Risk for Blood Transfusion After Total Joint Arthroplasty

NCT02926651
View directory record Official record
Conditions
Anemia, Arthritis, Total Knee Arthroplasty, Total Hip Arthroplasty
Interventions
Conventional Oral TXA (Tranexamic Acid), Multi-Dose Oral TXA (Tranexamic Acid)
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Sep 1, 2026, 9:19 PM EDT
Terminated No phase listed Interventional Results available

Real-Time Instrument for Acetabular Shell Positioning

NCT02006251
View directory record Official record
Conditions
Total Hip Arthroplasty
Interventions
Real-time Instrumentation, Standard Total Hip Arthroplasty
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Sep 1, 2026, 9:19 PM EDT
Completed Not applicable Interventional

Interventional Study Exploring the Occurrence of Surgical Site Infections.

NCT06661473
View directory record Official record
Conditions
Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
Interventions
Avance Solo Negative Pressure Wound Therapy
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
8
States / cities
Washington D.C., District of Columbia • Indianapolis, Indiana • Baltimore, Maryland + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 1, 2026, 9:19 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Assess the Mid-term Performance of the Mpact Cup in Subjects Requiring Total Hip Arthroplasty

NCT03897595
View directory record Official record
Conditions
Hip Osteoarthritis
Interventions
MPact Cup
Device
Lead sponsor
Medacta USA
Industry
Eligibility
Not listed
Enrollment
187 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2022
U.S. locations
5
States / cities
Parker, Colorado • Boise, Idaho • Libertyville, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2023 · Synced Sep 1, 2026, 9:19 PM EDT
Completed Phase 4 Interventional Results available

Time of Intravenous Acetaminophen Administration

NCT01699815
View directory record Official record
Conditions
Osteoarthritis
Interventions
Acetaminophen
Drug
Lead sponsor
Duke University
Other
Eligibility
30 Years to 75 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 4, 2014 · Synced Sep 1, 2026, 9:19 PM EDT
Enrolling by invitation Early Phase 1 Interventional

Quadratus Lumborum Block for Total Hip Arthroplasty

NCT05247255
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Active Comparator, Placebo Comparator
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 1, 2026, 9:19 PM EDT
Not listed Not applicable Interventional

KINCISE™ Surgical Automated System in Total Hip Arthroplasty (THA)

NCT05223777
View directory record Official record
Conditions
Osteoarthritis, Hip
Interventions
KINCISE, Traditional Handheld Mallet
Device
Lead sponsor
University of Cincinnati
Other
Eligibility
21 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2022 · Synced Sep 1, 2026, 9:19 PM EDT
Completed Phase 4 Interventional Results available

Psoas Compartment Block Versus Periarticular Local Anesthetic for Total Hip Arthroplasty

NCT02658149
View directory record Official record
Conditions
Osteoarthritis, Arthroplasty
Interventions
Ropivacaine with NaCl, Epinephrine, Morphine, Ketorolac Tromethamine, Ropivacaine
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 8, 2018 · Synced Sep 1, 2026, 9:19 PM EDT
Completed No phase listed Observational

Evaluation of Bone Mineral Density Changes After Total Hip Replacement: A Two-Year Clinical and DXA Analysis

NCT02865447
View directory record Official record
Conditions
Joint Disease
Interventions
total hip arthroplasty implant
Device
Lead sponsor
MicroPort Orthopedics Inc.
Industry
Eligibility
21 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 1, 2026, 9:19 PM EDT
Not listed No phase listed Observational

Tissue Culture Versus Swab Culture in Prosthetic Joint Infections

NCT01482533
View directory record Official record
Conditions
Revision Total Hip Arthroplasty, Revision Total Knee Arthroplasty
Interventions
Not listed
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 29, 2011 · Synced Sep 1, 2026, 9:19 PM EDT