- Conditions
- Shoulder Arthroplasty
- Interventions
- Liposomal bupivacaine, Bupivacaine with adjuvants
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
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Showing 1–24
of 1,047
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Total Knee Arthroplasty
- Interventions
- Methadone
- Drug
- Lead sponsor
- AdventHealth
- Other
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 192 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Denver, Colorado
- Conditions
- Knee Injuries
- Interventions
- Spinal Surgery, Verasense Knee System device
- Procedure · Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Ankle Arthritis, Ankle Arthropathy
- Interventions
- Intra-articular injection, Peripheral nerve block
- Procedure
- Lead sponsor
- Slocum Research & Education Foundation
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Eugene, Oregon
- Conditions
- Osteoarthritis of Hip
- Interventions
- No hip precautions
- Procedure
- Lead sponsor
- West Virginia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 321 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- Morgantown, West Virginia
- Conditions
- Total Knee Arthroplasty, Osteoarthritis
- Interventions
- Neuromuscular electrical stimulation, Voluntary exercise
- Procedure
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 45 Years to 85 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2002
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Arthroplasty, Replacement, Shoulder
- Interventions
- Reverse Total Shoulder
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 168 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 19
- States / cities
- Irvine, California • Los Angeles, California • Atlantis, Florida + 16 more
- Conditions
- Total Knee Arthroplasty, Post-operative Pain Control
- Interventions
- Liposomal Bupivacaine Peri-articular Injection, Adductor canal block
- Procedure
- Lead sponsor
- Good Samaritan Regional Medical Center, Oregon
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Corvallis, Oregon
- Conditions
- Knee Arthritis
- Interventions
- Customized Patient Instrumentation, Traditional Instrumentation
- Device
- Lead sponsor
- Anderson Orthopaedic Research Institute
- Other
- Eligibility
- Not listed
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Alexandria, Virginia
- Conditions
- Knee Osteoarthritis
- Interventions
- Liposomal bupivacaine, Ropivacaine, Epinephrine, Clonidine, Saline
- Drug
- Lead sponsor
- The Hawkins Foundation
- Other
- Eligibility
- 18 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015
- U.S. locations
- 1
- States / cities
- Greenville, South Carolina
- Conditions
- Osteoarthritis
- Interventions
- OrthoSensor Verasense Technology
- Device
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 40 Years to 100 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Triathlon TS Knee System
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 180 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2019
- U.S. locations
- 12
- States / cities
- Phoenix, Arizona • Jacksonville, Florida • Chicago, Illinois + 9 more
- Conditions
- Osteoarthritis, Knee
- Interventions
- Ropivacaine, Ketorolac, Clonidine, Epinephrine, 0.9% sodium chloride
- Drug
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 64 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2021
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Postoperative Pain, Total Knee Arthroplasty, Nerve Block
- Interventions
- bupivacaine, saline
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis, Knee
- Interventions
- iTotal PS KRS
- Device
- Lead sponsor
- Restor3D
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2022
- U.S. locations
- 4
- States / cities
- Chapel Hill, North Carolina • Austin, Texas • Morrisville, Vermont + 1 more
- Conditions
- Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain)
- Interventions
- Transcranial Direct Current Stimulation, Cognitive-Behavioral (CB) intervention
- Device · Behavioral
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Arthroplasty
- Interventions
- Not listed
- Lead sponsor
- Stability Plus, LLC
- Industry
- Eligibility
- Not listed
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Anatomic Total Shoulder Arthroplasty
- Interventions
- Anatomic TSA using IRI Instrumentation, Anatomic Total Shoulder Arthroplasty
- Device · Procedure
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Osteoarthritis, Avascular Necrosis
- Interventions
- Total hip replacement components
- Device
- Lead sponsor
- New Lexington Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2023
- U.S. locations
- 1
- States / cities
- Lexington, Kentucky
- Conditions
- Arthritis of Knee
- Interventions
- Not listed
- Lead sponsor
- Athens Orthopedic Clinic, P.A.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 2
- States / cities
- Athens, Georgia
- Conditions
- Obstructive Sleep Apnea, Total Knee Arthroplasty
- Interventions
- Not listed
- Lead sponsor
- United States Naval Medical Center, San Diego
- Federal
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 93 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Knee Osteoarthritis, Musculoskeletal Disease, Surgery
- Interventions
- PAI, PAI + steroid, PAI + zilretta
- Drug
- Lead sponsor
- Walter Reed National Military Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- PONV
- Interventions
- Aprepitant Injection, Ondansetron (Zofran), Dexamethasone, Placebo
- Drug · Other
- Lead sponsor
- Endeavor Health
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 350 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Skokie, Illinois
- Conditions
- Total Knee Arthroplasty
- Interventions
- Intraosseous Vamcomycin Administration
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- San Diego, California