- Conditions
- Primary Total Hip Arthroplasty, Primary Total Knee Arthroplasty
- Interventions
- Diphenhydramine (Benadryl), Melatonin, Sleep Hygiene Education
- Drug · Dietary Supplement · Behavioral
- Lead sponsor
- James A. Keeney
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 49–72
of 815
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis Knees Both, Joint Inflammation
- Interventions
- Astaxanthin, Placebo
- Drug · Other
- Lead sponsor
- Prisma Health-Midlands
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Columbia, South Carolina
- Conditions
- Constipation
- Interventions
- Propylene Glycol, Docusate Sodium
- Drug
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 20 Years to 90 Years
- Enrollment
- 154 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Knee Arthroplasty, Total
- Interventions
- LEGION Hinge Knee System
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2028
- U.S. locations
- 3
- States / cities
- Iowa City, Iowa • New York, New York • Portland, Oregon
- Conditions
- Knee Osteoarthritis, Primary Total Knee Arthroplasty, Physical Therapy, Pain, Knee Extension
- Interventions
- Ropivacaine, Interspace Between the Popliteal Artery and Capsule of the Knee (iPACK) Block, Saline
- Drug · Procedure
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Total Knee Arthroplasty
- Interventions
- Ambulatory continuous femoral nerve block for 100 hours
- Procedure
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 81 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 3
- States / cities
- Berkeley, California • San Diego, California • Gainesville, Florida
- Conditions
- Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
- Interventions
- Consensus TracPatch
- Device
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Knee Osteoarthritis
- Interventions
- Blood Flow Restriction Training (BFRT)
- Procedure
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Urinary Retention
- Interventions
- integrated care pathway, physician's standard of care
- Other
- Lead sponsor
- TriHealth Inc.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 164 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2022
- U.S. locations
- 2
- States / cities
- Cincinnati, Ohio
- Conditions
- Arthropathy of Knee
- Interventions
- OCSI Rehabilitator brace
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 9 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Total Knee Arthroplasty
- Interventions
- Liposome Bupivacaine, Bupivacaine
- Drug
- Lead sponsor
- St. Luke's-Roosevelt Hospital Center
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis
- Interventions
- Modafinil, Gabapentin, Placebo
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Aseptic Loosening of Prosthetic Joint, Instability of Prosthetic Joint, Reimplantation for Periprosthetic Joint Infection, Femoral Revision Indicated, Tibial Component Revision
- Interventions
- Constrained Condylar bearing, posterior stabilized bearing
- Device
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2038
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis
- Interventions
- TKA with "Verasense", TKA without "Verasense"
- Device · Procedure
- Lead sponsor
- Orthosensor, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2020
- U.S. locations
- 6
- States / cities
- Weston, Florida • Atlanta, Georgia • Morton Grove, Illinois + 3 more
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Comprehensive Behavioral Intervention, Standard of Care Exercise Program
- Behavioral · Other
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis
- Interventions
- Robotic Arm Assisted Total Knee Arthroplasty
- Device
- Lead sponsor
- MAKO Surgical Corp.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 3
- States / cities
- St. Helena, California • Tampa, Florida • Houston, Texas
- Conditions
- Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Disease, Joint Pain, Osteo Arthritis Knee, Osteoarthritis, Knee
- Interventions
- ROMTech PortableConnect, Traditional Rehabilitation and CPM Device
- Device
- Lead sponsor
- ROM Technologies, INC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 300 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 5
- States / cities
- Gilbert, Arizona • Aventura, Florida • Clearwater, Florida + 2 more
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities, Rheumatoid Arthritis
- Interventions
- PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 181 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more
- Conditions
- Osteoarthritis, Sarcopenia
- Interventions
- Total knee replacement surgery
- Procedure
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Knee Replacement, Total Knee Arthroplasty, Post-Operative Pain
- Interventions
- Liposomal bupivacaine, Bupivacaine
- Drug
- Lead sponsor
- Northern Light Mercy Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 80 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Portland, Maine
- Conditions
- Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative
- Interventions
- Methylprednisolone 4 milligram Tab, Dexamethasone injection
- Drug
- Lead sponsor
- F. Johannes Plate
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
- Conditions
- Knee Osteoarthritis, Arthroplasty Complications
- Interventions
- Treadmill-based perturbation training, Education Control
- Behavioral
- Lead sponsor
- University of Illinois at Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Pain, Postoperative, Satisfaction
- Interventions
- Ropivacaine
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 164 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Physical Activity
- Interventions
- Fitbit®, Physical Therapy Rehab
- Behavioral · Other
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Newark, Delaware