- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Femoral nerve catheter and sciatic nerve block, Adductor canal catheter and selective tibial block, Adductor canal catheter only
- Drug
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 367
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Knee Arthritis
- Interventions
- Simplex® Bone Cement, Cobalt™ Bone Cement
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Warsaw, Indiana
- Conditions
- Postoperative Analgesia, Medial Unicompartmental Knee Arthroplasty
- Interventions
- Adductor canal block, Lumbar plexus block
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Total Knee Arthroplasty; Total Hip Arthroplasty
- Interventions
- Health Partner, Standard Care
- Behavioral
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 79 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 3
- States / cities
- Newberg, Oregon • Spokane, Washington
- Conditions
- Total Knee Arthroplasty, Post-operative Edema
- Interventions
- Manual Lymphatic Drainage, Physical Therapy
- Other
- Lead sponsor
- Anne Arundel Health System Research Institute
- Other
- Eligibility
- 45 Years to 90 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Annapolis, Maryland
- Conditions
- Total Knee Arthroplasty Revision, Inflammatory Markers, Gut Microbiota
- Interventions
- Assigned Interventions
- Dietary Supplement
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Rheumatoid Arthritis
- Interventions
- Total Knee Arthroplasty
- Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 299 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2033
- U.S. locations
- 12
- States / cities
- Atlanta, Georgia • Boston, Massachusetts • Novi, Michigan + 8 more
- Conditions
- Knee Arthroplasty, Total, Post Operative Pain, Acute, Opioid Consumption, Postoperative
- Interventions
- Suzetrigine, Opioid standard care pain medicine
- Drug
- Lead sponsor
- Endeavor Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Skokie, Illinois
- Conditions
- Pain, Postoperative, Arthroplasty, Replacement, Knee, Osteoarthritis
- Interventions
- Liposomal bupivacaine, bupivacaine HCl, morphine, epinephrine, methylprednisolone
- Drug
- Lead sponsor
- Miller Orthopedic Specialists
- Other
- Eligibility
- 18 Years to 90 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Council Bluffs, Iowa
- Conditions
- Osteoarthritis
- Interventions
- Neuromuscular Electrical Stimulation (NMES), Standard Rehabilitation Protocol
- Device · Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Knee Replacement
- Interventions
- Phone Coaching, Progress reports to providers, 'Hear from Others' Videos, Individualized Feedback, Online exercise program
- Behavioral
- Lead sponsor
- University of South Carolina
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 336 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- Columbia, South Carolina
- Conditions
- Post Operative Pain
- Interventions
- F14, 0.25 % Bupivacaine HCl, Acetaminophen, Methocarbamol
- Drug
- Lead sponsor
- Arthritis Innovation Corporation
- Industry
- Eligibility
- 45 Years to 80 Years
- Enrollment
- 151 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 7
- States / cities
- Little Rock, Arkansas • Tamarac, Florida • Tulsa, Oklahoma + 4 more
- Conditions
- Osteoarthritis
- Interventions
- Tranexamic Acid (TXA), ε-Aminocaproic Acid (EACA)
- Drug
- Lead sponsor
- Miller Orthopedic Specialists
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 194 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Council Bluffs, Iowa
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Music Therapy
- Other
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Partial Knee Replacement
- Interventions
- Cementless fixation
- Procedure
- Lead sponsor
- Anderson Orthopaedic Research Institute
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Alexandria, Virginia
- Conditions
- Arthritis of Knee
- Interventions
- Not listed
- Lead sponsor
- Athens Orthopedic Clinic, P.A.
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 2
- States / cities
- Athens, Georgia
- Conditions
- Postoperative Pain, Total Knee Replacement, Total Knee Arthroplasty, Partial Knee Replacement
- Interventions
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Device
- Lead sponsor
- SPR Therapeutics, Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 10
- States / cities
- Little Rock, Arkansas • San Diego, California • Gainesville, Florida + 7 more
- Conditions
- Arthroplasty, Replacement
- Interventions
- Chlora Prep, Dura Prep
- Other
- Lead sponsor
- Texas Tech University Health Sciences Center
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 77 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2020
- U.S. locations
- 1
- States / cities
- Lubbock, Texas
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
- Interventions
- Intra-articular Posteromedial Surgeon Administered (IPSA) Block with LIA, Local Infiltration Analgesia (LIA), Bupivacaine liposome injectable suspension (IPSA block), Bupivacaine liposome injectable suspension (LIA)
- Procedure · Drug
- Lead sponsor
- Cedars-Sinai Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Osteoarthritis
- Interventions
- Patient record review, Radiographs, and questionaires.
- Other
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- Not listed
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Boise, Idaho
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Triathlon Tritanium Cone Augments
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 254 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2028
- U.S. locations
- 9
- States / cities
- Zephyrhills, Florida • Chicago, Illinois • Lexington, Kentucky + 6 more
- Conditions
- Pain, Postoperative
- Interventions
- N1539, Placebo
- Drug
- Lead sponsor
- Baudax Bio
- Industry
- Eligibility
- 35 Years to 80 Years
- Enrollment
- 194 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 6
- States / cities
- Florence, Alabama • Mobile, Alabama • Sheffield, Alabama + 3 more
- Conditions
- Arthroplasties, Knee Replacement
- Interventions
- Inelastic adjustable compression garment (INCOM), Elastic compression garment (CONTROL)
- Other
- Lead sponsor
- University of Colorado, Denver
- Other
- Eligibility
- 50 Years to 120 Years
- Enrollment
- 58 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2026
- U.S. locations
- 2
- States / cities
- Aurora, Colorado • Denver, Colorado
- Conditions
- Postoperative Pain, Total Knee Arthroplasty, Nerve Block
- Interventions
- bupivacaine, saline
- Drug
- Lead sponsor
- Northwestern University
- Other
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2021
- U.S. locations
- 1
- States / cities
- Chicago, Illinois