- Conditions
- Antibotics in Cementless Knees
- Interventions
- Tobramycin Powder, Vancomyscin
- Drug · Device
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Total Knee Replacement, Wound Complication
- Interventions
- Skin closure using skin adhesive, Skin closure without skin adhesive
- Procedure
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 216 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Osteoarthritis, Knee, Arthritis, Pain
- Interventions
- EMPI Select TENS, Placebo EMPI Select TENS
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Postsurgical Pain
- Interventions
- Placebo Injection, AYX1 Injection 110 mg, AYX1 Injection 330 mg
- Drug
- Lead sponsor
- Adynxx, Inc.
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 7
- States / cities
- Sheffield, Alabama • Phoenix, Arizona • Boynton Beach, Florida + 4 more
- Conditions
- Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 40 Years to 90 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2025
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Osteo Arthritis Knee, Central Nervous System Sensitization
- Interventions
- Pregabalin 75mg
- Drug
- Lead sponsor
- University of Iowa
- Other
- Eligibility
- 50 Years to 85 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa
- Conditions
- Osteoarthritis
- Interventions
- Evaluation of Augmented Reality technology in TKA compared to standard TKA
- Other
- Lead sponsor
- Foundation for Orthopaedic Research and Education
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Arthroplasty, Replacement, Knee, Nerve Block
- Interventions
- Adductor Canal Block, Bupivacaine, Femoral Nerve Block, Bupivacaine
- Procedure
- Lead sponsor
- George Macrinici
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 106 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Joliet, Illinois
- Conditions
- Analgesia
- Interventions
- HTX-011, Ibuprofen, Acetaminophen, Celecoxib, +/- Bupivacaine HCl, Luer Lock Applicator
- Drug · Device
- Lead sponsor
- Heron Therapeutics
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 116 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 6
- States / cities
- Sheffield, Alabama • Tamarac, Florida • Dayton, Ohio + 3 more
- Conditions
- Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Interventions
- Liposomal bupivacaine, 266mg, Bupivacaine 0.5 % with Epinephrine, Ketorolac 30mg, Morphine 10mg, Bupivacaine 0.25% with Epinephrine
- Drug
- Lead sponsor
- Holy Cross Hospital, Florida
- Other
- Eligibility
- 18 Years to 88 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Fort Lauderdale, Florida
- Conditions
- Total Knee Replacement
- Interventions
- Kneehab XP, Quadriceps TENS
- Device
- Lead sponsor
- Theragen Inc.
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Greenville, South Carolina
- Conditions
- Knee Osteoarthritis, Musculoskeletal Disease, Surgery
- Interventions
- PAI, PAI + steroid, PAI + zilretta
- Drug
- Lead sponsor
- Walter Reed National Military Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- Total Knee Replacement, Total Knee Arthroplasty, Pain, Postoperative Pain, Orthopedic Disorders
- Interventions
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Device
- Lead sponsor
- SPR Therapeutics, Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2017
- U.S. locations
- 3
- States / cities
- La Jolla, California • Durham, North Carolina • New Albany, Ohio
- Conditions
- Knee Injuries
- Interventions
- Journey II BCS TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2016
- U.S. locations
- 3
- States / cities
- Knoxville, Tennessee
- Conditions
- Osteo Arthritis Knee, Total Knee Replacement
- Interventions
- Total Knee Arthroplasty using LEGION™ Total Knee System
- Procedure
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 128 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2020
- U.S. locations
- 5
- States / cities
- Vero Beach, Florida • Des Moines, Iowa • Louisville, Kentucky + 2 more
- Conditions
- Osteo Arthritis Knee
- Interventions
- Isotonic saline, Ketamine Injectable Solution
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- Not listed
- Enrollment
- 75 participants
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Pain, Postoperative, Total Knee Arthroplasty
- Interventions
- Duloxetine, Placebos
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 241 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Total Knee Arthroplasty, Osteo Arthritis Knee, Knee Injuries, Knee Imlant
- Interventions
- MicroPort Medial Pivot TKA, DePuy Attune PCR TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 3
- States / cities
- Las Vegas, Nevada • Knoxville, Tennessee
- Conditions
- Pain, Total Knee Replacement, Total Hip Replacement
- Interventions
- Gabapentin, Placebo
- Drug
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 350 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Knee
- Interventions
- Triathlon PCR TKA, Triathlon PS TKA, Persona PCR TKA, Persona PS TKA
- Device
- Lead sponsor
- The University of Tennessee, Knoxville
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 2
- States / cities
- Knoxville, Tennessee
- Conditions
- Total Knee Arthroplasty
- Interventions
- 3D-Printed Mechanical Balancer
- Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Total Knee Arthroplasty Postoperative Pain, Opioid Reduction After TKA
- Interventions
- NEUROCUPLE™ Patch, Sham patch, Enhanced Recovery After Surgery (ERAS) Standard of Care
- Device · Other
- Lead sponsor
- Jacques E. Chelly
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 274 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 3
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Total Knee Replacement, Knee Arthroplasty
- Interventions
- Bupivacaine-Liposomal Bupivacaine, Bupivacaine -Dexamethasone Sodium Phosphate-Methylprednisolone Acetate
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 250 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2028
- U.S. locations
- 2
- States / cities
- New Haven, Connecticut
- Conditions
- Pain, Arthrofibrosis, Osteoarthritis, Knee
- Interventions
- Hydrocortisone, Dextrose 5% in water (D5W)
- Drug
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years to 83 Years
- Enrollment
- 132 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York