- Conditions
- Surgical Wound, Revision Total Knee Arthroplasty, Wounds and Injuries, Joint Disease, Musculoskeletal Disease, Prosthesis-Related Infections, Infection, Postoperative Complications, Pathologic Processes
- Interventions
- Closed Incision Negative Pressure Therapy (ciNPT), Standard of Care Dressing
- Device
- Lead sponsor
- KCI USA, Inc
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 294 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 17
- States / cities
- Weston, Florida • Tucker, Georgia • New Orleans, Louisiana + 10 more
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 27
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Prosthetic-joint Infection, Arthroplasty Complications
- Interventions
- Treatment of Chronic TKA PJI
- Procedure
- Lead sponsor
- University of Pittsburgh
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Total Knee Replacement Revision
- Interventions
- LEGION OXINIUM, LEGION Cobalt Chrome
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- Not listed
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2025
- U.S. locations
- 2
- States / cities
- Egg Harbor, New Jersey • New York, New York
- Conditions
- Total Knee Arthroplasty Revision, Inflammatory Markers, Gut Microbiota
- Interventions
- Assigned Interventions
- Dietary Supplement
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Arthropathy of Knee Joint
- Interventions
- Vancomycin
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Total Knee Arthroplasty, Prosthetic-joint Infection, Irrigation
- Interventions
- Methylene Blue 10 MG/ML (intra-articular application), Revision Arthroplasty for PJI (DAIR), Primary Total Knee Arthroplasty
- Drug · Procedure
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Primary Knee Arthroplasty
- Interventions
- ATTUNE Revision Knee System in Total Knee Arthroplasty
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2030
- U.S. locations
- 15
- States / cities
- San Diego, California • Denver, Colorado • Fort Collins, Colorado + 12 more
- Conditions
- Prosthesis-Related Infections, Arthroplasty
- Interventions
- Betadine Lavage, Saline Lavage
- Procedure
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 505 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2019
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Winfield, Illinois
- Conditions
- Revision Total Knee Arthroplasty
- Interventions
- ATTUNE Revision Knee System in Revision Total Knee Arthroplasty
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2029
- U.S. locations
- 16
- States / cities
- San Diego, California • Denver, Colorado • Fort Collins, Colorado + 13 more
- Conditions
- Revision Total Knee Arthroplasty
- Interventions
- Nerve Block for pain control post-revision total knee arthroplasty
- Procedure
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 51 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Total Knee Arthroplasty, Total Hip Arthroplasty Revision, Total Knee Arthroplasty Revision
- Interventions
- Avance Solo Negative Pressure Wound Therapy
- Device
- Lead sponsor
- Molnlycke Health Care AB
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 104 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 8
- States / cities
- Washington D.C., District of Columbia • Indianapolis, Indiana • Baltimore, Maryland + 5 more
- Conditions
- Total Knee Arthroplasty
- Interventions
- 3D Metal Tibial and Femoral cones
- Device
- Lead sponsor
- Medacta International SA
- Industry
- Eligibility
- Not listed
- Enrollment
- 118 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis
- Interventions
- Patient record review, Radiographs, and questionaires.
- Other
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- Not listed
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2022
- U.S. locations
- 1
- States / cities
- Boise, Idaho
- Conditions
- Aseptic Loosening of Prosthetic Joint, Instability of Prosthetic Joint, Reimplantation for Periprosthetic Joint Infection, Femoral Revision Indicated, Tibial Component Revision
- Interventions
- Constrained Condylar bearing, posterior stabilized bearing
- Device
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2038
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Aseptic Revision Knee Arthroplasty, Stiffness Following Revision Knee Arthroplasty
- Interventions
- Knee immobilizer, No Knee Immobilizer
- Device
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Failed Total Knee Arthroplasty
- Interventions
- Vitagel
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Joint Disease
- Interventions
- Total Knee Arthroplasty (EVOLUTION®)
- Device
- Lead sponsor
- MicroPort Orthopedics Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2028
- U.S. locations
- 1
- States / cities
- Morton Grove, Illinois
- Conditions
- Total Knee Replacement
- Interventions
- Not listed
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- Started 2010
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Prosthesis-Related Infections
- Interventions
- Oral Antibiotics
- Other
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 185 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2020
- U.S. locations
- 4
- States / cities
- Chicago, Illinois • Winfield, Illinois • Philadelphia, Pennsylvania + 1 more
- Conditions
- Prosthesis-related Infections, Wound Complications, Joint Diseases, Musculoskeletal Diseases
- Interventions
- Prevena
- Device
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Revision Total Hip Arthroplasty, Revision Total Knee Arthroplasty
- Interventions
- Not listed
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Arthroplasties, Knee Replacement, Revision Arthroplasty
- Interventions
- Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex UC, Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex PS, Omnibotics Robotic-assisted Total Knee Arthroplasty with Apex Revision
- Device
- Lead sponsor
- Corin
- Industry
- Eligibility
- Not listed
- Enrollment
- 713 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2040
- U.S. locations
- 6
- States / cities
- Flagstaff, Arizona • Middlebury, Connecticut • Rochester, Michigan + 3 more
- Conditions
- Knee Osteoarthritis
- Interventions
- VERASENSE
- Procedure
- Lead sponsor
- Orthosensor, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018
- U.S. locations
- 1
- States / cities
- Fort Lauderdale, Florida
- Conditions
- Revision Total Knee Arthroplasty, Revision Total Hip Arthroplasty, Acute Blood Loss Anemia
- Interventions
- Revision Total Knee Arthroplasty (TKA), Revision Total Hip Arthroplasty (THA)
- Procedure
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 3
- States / cities
- Chicago, Illinois • Rochester, Minnesota • New York, New York