- Conditions
- Joint Replacement Surgery
- Interventions
- Normal Saline 10 mL Injection
- Drug
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Osteoarthritis, Degenerative Joint Disease
- Interventions
- Motivational Interviewing (MI), Financial Incentives
- Behavioral · Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 40 Years and older
- Enrollment
- 202 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Degenerative Joint Disease, Osteoarthritis
- Interventions
- PEAK PlasmaBlade 4.0, Traditional Electrosurgery with scalpel
- Device
- Lead sponsor
- Medtronic Surgical Technologies
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 2
- States / cities
- Rochester Hills, Michigan • Arlington, Texas
- Conditions
- Osteoarthritis, Knee
- Interventions
- Device: Robotic MAKO total knee, FocusMotion knee brace, Fitbit tracking device, FocusMotion app
- Device
- Lead sponsor
- Washington University School of Medicine
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 123 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Creve Coeur, Missouri
- Conditions
- Osteoarthritis, Knee
- Interventions
- TSolution One®
- Device
- Lead sponsor
- Think Surgical Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 115 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 6
- States / cities
- Hackensack, New Jersey • New York, New York • Roslyn, New York + 3 more
- Conditions
- Osteoarthritis
- Interventions
- GUIDED IMAGERY, PLACEBO
- Behavioral
- Lead sponsor
- Kent State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 82 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 1
- States / cities
- Akron, Ohio
- Conditions
- Hypnosis, Perioperative Care, Knee Arthroplasty, Total, Postoperative Pain, Postoperative Complications
- Interventions
- Hypnosis
- Behavioral
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Palo Alto, California
- Conditions
- Osteoarthritis, Sarcopenia
- Interventions
- Total knee replacement surgery
- Procedure
- Lead sponsor
- University of Florida
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 18 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Gainesville, Florida
- Conditions
- Pain, Total Knee Arthroplasty
- Interventions
- Dexamethasone, Ropivacaine
- Drug
- Lead sponsor
- University of New Mexico
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Albuquerque, New Mexico
- Conditions
- Osteo Arthritis Knee, Total Knee Arthroplasty
- Interventions
- MyKnee with single use Efficiency Instrument, Stryker Navigational with conventional metal instruments
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 16 Years to 75 Years
- Enrollment
- 82 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Indianapolis, Indiana
- Conditions
- Drainage
- Interventions
- Duraprep Surgical Solution
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2012
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Anesthesia
- Interventions
- Audiovisual Distraction
- Other
- Lead sponsor
- University of Utah
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Osteoarthritis, Knee
- Interventions
- DePuy ATTUNE total knee arthroplasty system
- Device
- Lead sponsor
- Kristin Zhao, PhD
- Other
- Eligibility
- 40 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Knee Osteoarthritis
- Interventions
- Femoral Nerve Catheters, Single Shot Femoral Nerve Blocks
- Drug
- Lead sponsor
- Eastern Maine Medical Center
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 99 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Bangor, Maine
- Conditions
- Pain Management, Function, Minimally Invasive Total Knee Arthroplasty, Celecoxib
- Interventions
- Celecoxib
- Drug
- Lead sponsor
- St. Louis Joint Replacement Institute
- Other
- Eligibility
- Not listed
- Enrollment
- 107 participants
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- St Louis, Missouri
- Conditions
- Arthroplasty, Replacement, Knee, Injuries, Knee
- Interventions
- Cutting Guide Technique, Haptic Feedback Technique, Four Quadrant Technique
- Procedure
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Surgical Blood Loss
- Interventions
- Saline-coupled Bipolar Sealer, Unipolar electrocautery
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 211 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Syosset, New York
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- YM150, Warfarin
- Drug
- Lead sponsor
- Astellas Pharma Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 685 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 44
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Tuscon, Arizona + 35 more
- Conditions
- Osteoarthritis: Joint Replacement Surgery
- Interventions
- CLARIX FLO, Saline
- Other
- Lead sponsor
- BioTissue Holdings, Inc
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Orange Park, Florida
- Conditions
- Venous Thromboembolism
- Interventions
- GW813893
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years to 85 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2007
- U.S. locations
- 8
- States / cities
- Birmingham, Alabama • Phoenix, Arizona • Yuba City, California + 4 more
- Conditions
- Osteoarthritis
- Interventions
- Customized patient instruments, Traditional Metal Instruments
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2022
- U.S. locations
- 5
- States / cities
- Marrero, Louisiana • Billings, Montana • Meadville, Pennsylvania + 2 more
- Conditions
- Osteoarthritis
- Interventions
- Arthroscopic partial menisectomy, Standard physical therapy, Postoperative rehabilitative physical therapy
- Procedure · Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 45 Years and older
- Enrollment
- 351 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2025
- U.S. locations
- 7
- States / cities
- Chicago, Illinois • Boston, Massachusetts • Rochester, Minnesota + 4 more
- Conditions
- Knee Osteoarthristis
- Interventions
- Cognitive-Behavioral Therapy for Insomnia, Bright Light therapy via the Re-Timer®, Negative Ion exposure via IonMi Device, Sleep / Knee Osteoarthritis Education
- Behavioral · Device
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 252 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2029
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Chestnut Hill, Massachusetts
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
- Interventions
- POPOP (preoperative patient optimization program), SOC (standard of care)
- Other
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 46 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas