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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Total Shoulder Arthroplasty Clear all
Recruiting Not applicable Interventional

Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After Receiving a Reverse Total Shoulder Arthroplasty (RTSA)

NCT07125833
View directory record Official record
Conditions
Degenerative Joint Disease of Shoulder
Interventions
Cryoneurolysis, No cryoneurolysis
Device · Other
Lead sponsor
North Texas Medical Research Institute, PLLC
Other
Eligibility
30 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rockwall, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Terminated Not applicable Interventional

Onlay Versus Inlay Humeral Component in Reverse Total Shoulder Arthroplasty

NCT05297305
View directory record Official record
Conditions
Arthritis Shoulder, Rotator Cuff Injuries
Interventions
Tornier Ascend Flex stem, Tornier Perform Stem Reverse+
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting No phase listed Observational

Hospital for Special Surgery Shoulder Arthroplasty Cohort

NCT00527839
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue

NCT06733480
View directory record Official record
Conditions
Rotator Cuff Tears, Anatomic Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
Interventions
Band Connect
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
499 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational Results available

Post- Surgery Recovery: Nerve Blocks w/ Sedation vs. Nerve Block w/ Either Sedation/Gen. Anesthesia

NCT02602080
View directory record Official record
Conditions
Nausea, Emesis
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Jun 10, 2026, 2:12 PM EDT
Terminated Phase 4 Interventional

Pain Management After Total Shoulder Arthroplasty

NCT03219983
View directory record Official record
Conditions
Glenohumeral Arthritis, Total Shoulder Arthroplasty
Interventions
Ropivacaine, liposomal bupivacaine
Drug
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational

Glenoid Bone Grafting for RTSA: Clinical & Radiographic Outcomes

NCT03151109
View directory record Official record
Conditions
Osteo Arthritis Shoulders
Interventions
CT Scan
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational

Comparison of Pain Relief After Non Stimulating Interscalene Catheter Placement vs Stimulating Catheter Placement in Total Shoulder Arthroplasty.

NCT01122732
View directory record Official record
Conditions
Pain, Shoulder, Arthroplasty
Interventions
Not listed
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 90 Years
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 31, 2016 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Long Term Outcomes Follow-up of Glenoid Anchor Peg Component Fixation

NCT02983357
View directory record Official record
Conditions
Arthritis
Interventions
CT, X-Ray, Physical assessment, Questionnaire
Radiation · Other
Lead sponsor
University of Nebraska
Other
Eligibility
44 Years to 94 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

NCT05868330
View directory record Official record
Conditions
Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
Interventions
Interscalene Catheter, Exparel Single Shot Interscalene Block
Procedure
Lead sponsor
Melinda Seering
Other
Eligibility
18 Years to 90 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Not yet recruiting Phase 2 Interventional

Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty

NCT07138898
View directory record Official record
Conditions
Rheumatic Disease
Interventions
Methotrexate, Sulfasalazine, Hydroxychloroquine, Leflunomide, Azathioprine, Mycophenolate, Cyclosporine, Tacrolimus, Etanercept, Adalimumab, Golimumab, Certolizumab, Infliximab, Rituximab, Belimumab, Tocilizumab, Anakinra, Canakinumab, Abatacept, Secukinumab, Ixekizumab, Bimekizumab, Ustekinumab, Guselkumab, Risankizumab, Tofacitinib, Upadacitinib
Drug · Biological
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Not listed No phase listed Observational

Outcomes Following Delta Xtend Reverse Shoulder System

NCT02014350
View directory record Official record
Conditions
Reverse Total Shoulder Arthroplasty
Interventions
DePuy Delta Xtend Reverse TSA
Device
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 17, 2013 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational

Reverse Shoulder Replacement: Age 60 or Younger Outcomes

NCT03148184
View directory record Official record
Conditions
Shoulder Arthritis
Interventions
shoulder x-ray
Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Liposomal Bupivacaine for Pain Control After Total Shoulder Arthroplasty

NCT02762071
View directory record Official record
Conditions
Osteoarthritis, Arthropathy, Shoulder Pain, Closed Fracture Proximal Humerus, Four Part
Interventions
Liposomal bupivacaine, Interscalene Nerve Block
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
20 Years to 100 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Columbia, Maryland • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational

A Retrospective Review of FloSeal Use in Total Shoulder Arthroplasty

NCT01726972
View directory record Official record
Conditions
Total Shoulder Arthroplasty, Glenohumeral Osteoarthritis
Interventions
Not listed
Lead sponsor
Western Orthopaedics Research and Education Foundation
Other
Eligibility
21 Years to 90 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

INHANCE Stemless Reverse Shoulder IDE

NCT06323980
View directory record Official record
Conditions
Arthroplasty, Replacement, Shoulder
Interventions
Reverse Total Shoulder
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
22 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
19
States / cities
Irvine, California • Los Angeles, California • Atlantis, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Enrolling by invitation Not applicable Interventional

Pyrocarbon Hemiarthroplasty Versus Total Shoulder Arthroplasty for the Treatment of Glenohumeral Osteoarthritis

NCT07226388
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Hemiarthroplasty with pyrocarbon, Anatomic total shoulder arthroplasty
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2040
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Dermabond PRINEO for Total Shoulder Arthroplasty

NCT03860181
View directory record Official record
Conditions
Surgical Wound, Shoulder Arthritis, Surgical Incision
Interventions
Subcuticular Sutures - Surgeon 1, Metal Staples - Surgeon 2, PRINEO - Surgeon 1, PRINEO - Surgeon 2
Procedure · Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2021 · Synced Jun 10, 2026, 2:12 PM EDT
Withdrawn Phase 4 Interventional

Improving Pain Management After Total Shoulder Replacement Using Bupivacaine Liposome

NCT04134442
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Shoulder Pain, Pain, Postoperative
Interventions
Bupivacaine Liposome Injection, Standard Therapy
Drug · Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional

Subscapularis Indocyanine Green Perfusion Pilot Study

NCT05179941
View directory record Official record
Conditions
Shoulder Pain, Shoulder Arthritis, Shoulder Arthroplasty
Interventions
Perfusion with Indocyanine green
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 3, 2023 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Phase 4 Interventional Results available

Opioid-Free Shoulder Arthroplasty

NCT03540030
View directory record Official record
Conditions
Opioid Use, Shoulder Osteoarthritis, Avascular Necrosis, Rotator Cuff Tear, Arthritis;Inflammatory
Interventions
Gabapentin, Celecoxib, toradol, acetaminophen, regional block, propofol, IV lidocaine, rocuronium, vecuronium, sevoflurane, desflurane
Drug
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
50 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Jun 10, 2026, 2:12 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Closure After Total Shoulder Arthroplasty: Prineo vs Dermabond

NCT03899753
View directory record Official record
Conditions
Shoulder Arthritis, Shoulder Arthropathy Associated With Other Conditions
Interventions
2-Octyl Cyanoacrylate and Mesh, 2-Octyl Cyanoacrylate
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Phase 3 Interventional Results available

Reverse Shoulder Prosthesis Study

NCT00764504
View directory record Official record
Conditions
Rotator Cuff Arthropathy, Failed Total Shoulder, Failed Hemi-arthroplasty
Interventions
Reverse Shoulder Prosthesis
Device
Lead sponsor
Encore Medical, L.P.
Industry
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
25
States / cities
Glendale, California • Orange, California • Denver, Colorado + 21 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2011 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Wound Irrigation Comparative Effectiveness Study

NCT06379919
View directory record Official record
Conditions
Cutibacterium Acnes Contamination
Interventions
Irrisept Irrigation, Saline Irrigation Solution Delivery
Procedure
Lead sponsor
Orthopaedic Education and Research Institute (dba Hoag Orthopedics)
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Jun 10, 2026, 2:12 PM EDT