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Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Tourniquet Clear all
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Tourniquet Pressure in Primary Total Knee Arthroplasty

NCT02830087
View directory record Official record
Conditions
Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
Interventions
Tourniquet Cuff Pressure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
2
States / cities
Bermuda Run, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sensation and Skin Pressures Under Blood-Draw Tourniquets

NCT03187041
View directory record Official record
Conditions
Skin Pressures Under Blood Draw-tourniquets
Interventions
Sensation and Skin Surface Pressures Under Blood-Draw Tourniquets
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Retention of Tourniquet Application Skills Following Participation in a Bleeding Control Course

NCT03762863
View directory record Official record
Conditions
Hemorrhage
Interventions
Tourniquet application skill retention
Device
Lead sponsor
Somerville Office of Emergency Management
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Somerville, New Jersey
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tourniquets Increase Proximal Pressure

NCT05324306
View directory record Official record
Conditions
Blood Pressure
Interventions
combat application tourniquets (CAT)
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 60 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 17, 2024 · Synced Sep 9, 2026, 9:06 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Quantification of Progenitor Cell Circulation Following Vascular Resistance Exercise Using Delfi Tourniquet System

NCT07213726
View directory record Official record
Conditions
Blood Flow Restriction (BFR) Training Effects
Interventions
Delfi Personalized Tourniquet System
Device
Lead sponsor
Andrews Research & Education Foundation
Other
Eligibility
18 Years to 45 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Gulf Breeze, Florida
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Femoral Peri-arterial Local Anesthetic Injection Decreases Tourniquet Associated Ischemic Hypertension

NCT03390426
View directory record Official record
Conditions
Tourniquet Hypertension, Intraoperative Hypertension, Total Ankle Arthroplasty, Ankle Fusion
Interventions
Mepivacaine, Perifemoral Injection of Local Anesthetic, Saline
Drug · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2021 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional

Tourniquet vs. Short Time Tourniquet in Primary Robotic Assisted TKA

NCT03942939
View directory record Official record
Conditions
Knee Arthropathy
Interventions
Primary Robotic-Assisted Total Knee Arthroplasty with a short tourniquet time, Primary Robotic-Assisted Total Knee Arthroplasty with the use of a tourniquet
Other
Lead sponsor
University of Louisville
Other
Eligibility
21 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Nov 3, 2020 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Tourniquet on Sensory Nerve Conduction Threshold (sNCT) and OxyNeuroGram (ONG) Index- A Volunteer Study

NCT01970839
View directory record Official record
Conditions
Sensory Nerve Conduction, Oxyneurogram Index
Interventions
tourniquet, sensory nerve conduction abnormality
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Control of Tourniquet Pain With an Axillary Ring of Subcutaneous Local Anesthetic

NCT01829399
View directory record Official record
Conditions
Application Site Discomfort, Medical Device Discomfort
Interventions
Bupivacaine with Epinephrine, Normal Saline
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Sep 9, 2026, 9:06 AM EDT
Withdrawn Phase 4 Interventional

Effects of Dexmedetomidine on Tourniquet Pain Associated With Lower Extremity Surgeries Under General Anesthesia

NCT00932386
View directory record Official record
Conditions
Orthopedic/Podiatry Procedures
Interventions
Dexmedetomidine Hcl infusion, normal saline
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lower Tourniquet Pressure Study

NCT04994405
View directory record Official record
Conditions
Hand Injuries, Upper Extremity Injury
Interventions
Tourniquet Pressure
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 100 Years
Enrollment
93 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
3
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional

Ultrasound Guided Sciatic Nerve Block

NCT02688439
View directory record Official record
Conditions
Sciatic Nerve
Interventions
Sciatic Nerve block, Leg raised 30°, Distal tourniquet placed on the lower part of the leg, Leg in a neutral position
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 70 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2019 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurologic Examination of Wide and Narrow Tourniquets

NCT02023476
View directory record Official record
Conditions
Nerve Compression
Interventions
MRI
Radiation
Lead sponsor
Medical University of Vienna
Other
Eligibility
18 Years to 45 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 9, 2014 · Synced Sep 9, 2026, 9:06 AM EDT
Recruiting Not applicable Interventional

Correlation Between Intraoperative Tourniquet Use and Limb pH, Functional Measures and Patient-reported Outcomes After Ankle Fracture Surgery

NCT05445960
View directory record Official record
Conditions
Ankle Fractures, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar, Ankle Fracture - Medial Malleolus, Maisonneuve's Fracture, Syndesmotic Injuries, Fibula Fracture
Interventions
Tourniquet
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years
Enrollment
390 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional

Timing of Tourniquet Release

NCT06576869
View directory record Official record
Conditions
Injury
Interventions
Upper extremity orthopedic surgeries.
Procedure
Lead sponsor
Orlando Health, Inc.
Other
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional

Multimodal DVT Protocol in Tourniquet-less Total Knee Arthroplasty

NCT02102828
View directory record Official record
Conditions
Deep Vein Thrombosis
Interventions
extended compression, Aspirin
Device · Other
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Sep 9, 2026, 9:06 AM EDT
Withdrawn No phase listed Observational

Office Based Hand Surgery Using WALANT (Wide Awake Local Anesthesia No Tourniquet): Outcomes and Cost Savings Analysis

NCT02807571
View directory record Official record
Conditions
Surgery
Interventions
Wide Awake Local Anesthesia No Tourniquet
Procedure
Lead sponsor
Corewell Health West
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Tapping in the Venous Dilatation for Peripheral IV Access

NCT05265481
View directory record Official record
Conditions
Catheterization, Peripheral, Venous Dilatation
Interventions
Tourniquet, Manual Tapping, Device tapping
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Determine the Most Effective Intervention for Hemorrhage Control Readiness for Laypersons: The PATTS Trial

NCT03479112
View directory record Official record
Conditions
Traumatic Hemorrhage
Interventions
Flashcards, Audio-kit, B-Con training, B-Con training retention
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
562 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 9, 2026, 9:06 AM EDT
Terminated Not applicable Interventional

Tourniquet Use in Anterior Cruciate Ligament Repair

NCT05931627
View directory record Official record
Conditions
ACL - Anterior Cruciate Ligament Deficiency, ACL Injury, ACL Tear
Interventions
Patients undergoing ACL reconstruction with or without a tourniquet
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 9, 2026, 9:06 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Femoral Peri-arterial Local Anesthetic Injection Via Peri-arterial Perineural Catheter Reverses Tourniquet Associated Ischemic Hypertension

NCT04454203
View directory record Official record
Conditions
Tourniquet Hypertension, Intraoperative Hypertension, Total Ankle Arthroplasty, Ankle Fusion
Interventions
Mepivacaine, Saline, Perifemoral Injection of Local Anesthetic
Drug · Procedure
Lead sponsor
Duke University
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Performance of Junctional Tourniquets in Normal Human Volunteers

NCT01965561
View directory record Official record
Conditions
Hemorrhage
Interventions
CRoC, AAJT, JETT, SJT
Device
Lead sponsor
United States Army Institute of Surgical Research
Federal
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Forts Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 12, 2017 · Synced Sep 9, 2026, 9:06 AM EDT
Completed Not applicable Interventional Results available

Tourniquet on Total Knee Arthroplasty

NCT04923724
View directory record Official record
Conditions
Arthritis Knee
Interventions
tourniquet, No tourniquet
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Creve Coeur, Missouri
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Sep 9, 2026, 9:06 AM EDT
Completed No phase listed Observational

Pre-hospital Tourniquet in Extremity Injury

NCT04216225
View directory record Official record
Conditions
Extremity Injury
Interventions
pre-hospital tourniquet placement
Other
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
55 participants
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 9, 2026, 9:06 AM EDT