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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Transcranial Direct Current Stimulation Clear all
Completed Phase 1 Interventional

Home-administered tDCS for Treatment of Depression

NCT04781127
View directory record Official record
Conditions
Unipolar Depression, Treatment Resistant Depression
Interventions
Soterix Medical mini-CT tDCS stimulator
Device
Lead sponsor
Soterix Medical
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2023 · Synced Jun 26, 2026, 5:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA

NCT03887481
View directory record Official record
Conditions
Logopenic Progressive Aphasia, Primary Progressive Aphasia
Interventions
High-definition active tDCS (HD-tDCS) + "Repeat After Me" (RAM) Treatment, Sham + "Repeat After Me" (RAM) Treatment
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Non-invasive Brain Stimulation and Occupational Therapy To Enhance Stroke Recovery

NCT00792428
View directory record Official record
Conditions
Stroke, Cerebrovascular Accident, CVA, Acute Stroke, Acute Cerebrovascular Accident, Apoplexy
Interventions
Real Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2018 · Synced Jun 26, 2026, 5:03 AM EDT
Completed No phase listed Observational

Electrical Brain Stimulation to Reduce Epileptic Seizures

NCT00344877
View directory record Official record
Conditions
Temporal Lobe Epilepsy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiological and Functional Mechanisms of Motor Control and Learning

NCT03190590
View directory record Official record
Conditions
Transcranial Direct Current Stimulation
Interventions
tDCS-NeuroConn., TMS - Magstim., Sham tDCS
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced Jun 26, 2026, 5:03 AM EDT
Active, not recruiting Not applicable Interventional

Transcranial Direct Current Stimulation in Conjunction With Individualized Physical Therapy for Individuals With Chronic Knee Pain

NCT06132412
View directory record Official record
Conditions
Knee Pain Chronic
Interventions
transcranial direct current stimulation, physical therapy
Device · Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Not applicable Interventional

Spaulding-Harvard Model System: Effects of Transcranial Direct Current Stimulation (tDCS) on Chronic Pain in Spinal Cord Injury

NCT01599767
View directory record Official record
Conditions
Spinal Cord Injury, Chronic Pain, Neuropathic Pain
Interventions
Transcranial direct current stimulation (tDCS)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Jun 26, 2026, 5:03 AM EDT
Recruiting Not applicable Interventional

Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal

NCT04477330
View directory record Official record
Conditions
Stroke
Interventions
Transcranial direct current stimulation (tDCS), Ankle motor training, High intensity interval speed based treadmill training (HIISTT)
Other · Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jun 26, 2026, 5:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Transcranial Direct Current Stimulation (tDCS)-Enhanced Stroke Recovery

NCT01007136
View directory record Official record
Conditions
Ischemic Stroke
Interventions
tDCS, Sham tDCS
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Not applicable Interventional

tDCS for the Management of Multiple Sclerosis Related Fatigue

NCT03838770
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Active tDCS, sham tDCS
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Jun 26, 2026, 5:03 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Dose-Response Study of the Cognitive and Physiological Effects of tDCS to the DLPFC

NCT04175041
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Plus Spinal Stimulation for Cervical SCI

NCT04727866
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
Interventions
transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral, intermittent theta burst stimulation (iTBS)
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Jun 26, 2026, 5:03 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Facilitating Numerical Processing With Transcranial Stimulation in Developmental Dyscalculia

NCT01195961
View directory record Official record
Conditions
Cognition Disorder, Brain Mapping
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 26, 2026, 5:03 AM EDT
Recruiting Not applicable Interventional

RS-tDCS for Cannabis Use Disorder: The C.A.R.E.S. Initiative

NCT07184983
View directory record Official record
Conditions
Cannabis Use Disorder
Interventions
Active Transcranial Direct Current Stimulation (tDCS), Sham Transcranial Direct Current Stimulation (tDCS), Mindfulness meditation
Device · Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
22 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Phase 2 Interventional

Brain Monitoring, tDCS and Robotic Training in SCI

NCT06813287
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Electroencephalography (EEG), Upper extremity robot
Diagnostic Test · Device
Lead sponsor
Kathleen Friel
Other
Eligibility
16 Years to 65 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Jun 26, 2026, 5:03 AM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm

NCT01201629
View directory record Official record
Conditions
Brain Infarction, Brain Ischemia
Interventions
t DC stimulation, tDCStimulation
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
19 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Jun 26, 2026, 5:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia

NCT04142866
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Anodal transcranial direct current stimulation, Sham transcranial direct current stimulation, Speech-Language Therapy (SLT)
Device · Behavioral
Lead sponsor
City University of New York
Other
Eligibility
21 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Jun 26, 2026, 5:03 AM EDT
Withdrawn Not applicable Interventional

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

NCT02622945
View directory record Official record
Conditions
Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 25, 2018 · Synced Jun 26, 2026, 5:03 AM EDT
Recruiting Not applicable Interventional

Effects of Multiple-Session Transcranial Direct Current Stimulation (tDCS) on Behavioral, Physiological, and Electrophysiological Measures With Adults With Autism Spectrum Disorder (ASD)

NCT06495684
View directory record Official record
Conditions
Autism Spectrum Disorder, Autism or Autistic Traits
Interventions
Anodal tDCS + Social Learning, Placebo Anodal tDCS + Social Learning
Device · Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Jun 26, 2026, 5:03 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of PFC tDCS on Cognitive Control, Attention Lapses and Coordinated Neural Activity in the Theta and Alpha Bands

NCT04885322
View directory record Official record
Conditions
Healthy
Interventions
Transcranial Direct Current Stimulation
Device
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Not applicable Interventional Results available

Treating Primary Progressive Aphasia (PPA) Using tDCS

NCT04566731
View directory record Official record
Conditions
Primary Progressive Aphasia
Interventions
Transcranial Direct Current Stimulation (tDCS), Sham tDCS, Modified Contraint-Induced Language Therapy (mCILT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
45 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Not applicable Interventional

tDCS and Aphasia Treatment

NCT01922245
View directory record Official record
Conditions
Aphasia
Interventions
Soterix 1x1 tDCS
Device
Lead sponsor
Hunter College of City University of New York
Other
Eligibility
18 Years to 100 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Jun 26, 2026, 5:03 AM EDT
Completed Not applicable Interventional Results available

Optimizing Current and Electrode Montage for Transcranial Direct Current Stimulation in Stroke Patients

NCT02763826
View directory record Official record
Conditions
Stroke
Interventions
transcranial direct current stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Jun 26, 2026, 5:03 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

The Effect of tDCS on Subcortical Brain Functioning

NCT01602276
View directory record Official record
Conditions
Brain Damage, Chronic
Interventions
Transcranial Direct Current Stimulation (tDCS)
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 79 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Jun 26, 2026, 5:03 AM EDT