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ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:09 AM EDT

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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Transgenderism, Reproductive Issues
Interventions
Testosterone Cypionate 50 milligrams per millileter (mg/mL) Injectable Solution
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Diego, California
Completed No phase listed Observational Accepts healthy volunteers

Family Relationships and Nutrition in TGGD Youth and Young Adults

NCT05163860
Conditions
Family Relations, Nutrition Disorders, Health Behavior, Transgenderism
Interventions
Survey
Other
Lead sponsor
St. Louis University
Other
Eligibility
12 Years and older
Enrollment
714 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Enrolling by invitation Not applicable Interventional

MaPGAS Decision Making

NCT06565663
Conditions
Gender Dysphoria, Gender Dysphoria, Adult, Gender Incongruence, Transgenderism, Transsexualism, Transgender Persons, Phalloplasty
Interventions
MaPGAS Decision Aid
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Hanover, New Hampshire • Salt Lake City, Utah
Conditions
Transgenderism, Stigma, Social
Interventions
IDEAS (Identity Evolution and Sharing) Performance
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Transgender Men's Perspectives on HIV Risk and HIV Prevention Interventions

NCT05666102
Conditions
Transgenderism, HIV Infections
Interventions
Transgender men's perspectives on HIV risk and HIV prevention interventions
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Not listed No phase listed Observational Accepts healthy volunteers

Transgender Cohort Study of Gender Affirmation and HIV-related Health

NCT03595956
Conditions
HIV/AIDS, STI, Gender Dysphoria, Transsexualism, Gender Identity, Depression, Anxiety
Interventions
Medical gender affirmation
Other
Lead sponsor
Fenway Community Health
Other
Eligibility
18 Years and older
Enrollment
4,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Alcohol Use, Unspecified, Relationship, Social, Depression, Anxiety, Transgenderism
Interventions
Whole Selves
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 30 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Gender Incongruence, Transgenderism
Interventions
testosterone cypionate, Estradiol Valerate
Drug
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 50 Years
Enrollment
4 participants
Timeline
2020 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Terminated Early Phase 1 Interventional Accepts healthy volunteers

Coagulation and Fibrinolysis of Estradiol in Transwomen

NCT05387577
Conditions
Transgenderism, Clotting Disorder
Interventions
Estradiol Tablets, Transdermal patch
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Male only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Transphobia Among Adolescents Through a Brief Video Intervention

NCT04969003
Conditions
Transgenderism, Depression
Interventions
Short videos
Behavioral
Lead sponsor
Yale University
Other
Eligibility
14 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
New Haven, Connecticut
Conditions
Transgenderism, Gender Dysphoria, Insulin Sensitivity
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
13 Years to 16 Years
Enrollment
90 participants
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Microeconomic Intervention to Reduce HIV Transmission in Economically Disadvantaged Transgender Women

NCT04275310
Conditions
Hiv, Transgenderism
Interventions
Microeconomic Intervention
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Richmond, Virginia
Completed Not applicable Interventional Accepts healthy volunteers

Use of an External Erectile Device in Transgender Man Following Phalloplasty

NCT03823014
Conditions
Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
Interventions
Elator
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Transgenderism, Kidney Diseases, Kidney Injury
Interventions
p-aminohippurate clearance study, Iohexol infusion
Diagnostic Test
Lead sponsor
University of Colorado, Denver
Other
Eligibility
17 Years to 30 Years
Enrollment
22 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Transgenderism, Insulin Sensitivity/Resistance, Endothelial Dysfunction, Vascular Stiffness
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
9 Years to 14 Years · Male only
Enrollment
30 participants
Timeline
2020 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Androgen Effects on the Reproductive Neuroendocrine Axis

NCT06450405
Conditions
Transgenderism, Reproductive Issues
Interventions
Testosterone Cypionate 50 MG/ML Injectable Solution
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
San Diego, California
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Transgender Estradiol Affirming Therapy

NCT05010707
Conditions
Transgenderism
Interventions
Transdermal patch, Pro-thrombotic markers, Metabolic markers, Hormone Profile, Daily Sublingual Tablet, BID Sublingual Tablet, Spironolactone
Drug · Diagnostic Test
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Cardiometabolic Health in Transgender Males

NCT04977765
Conditions
Transgender, Transgenderism
Interventions
Not listed
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
12 Years to 30 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Milwaukee, Wisconsin