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ClinicalTrials.gov public records Last synced Sep 25, 2026, 4:54 AM EDT

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Showing 1–24 of 103 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Transplant; Failure, Heart Clear all
Active, not recruiting Not applicable Interventional

MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

NCT05933083
View directory record Official record
Conditions
Myocardial Infarction, Heart Failure, Systolic, Heart Valve Diseases, Angina, Stable, Coronary Artery Disease, Heart Transplant
Interventions
In-person cardiac rehabilitation, Telehealth cardiac rehabilitation
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
516 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
5
States / cities
San Francisco, California • Denver, Colorado • Baltimore, Maryland + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 25, 2026, 4:54 AM EDT
Active, not recruiting Not applicable Interventional

Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates

NCT03674307
View directory record Official record
Conditions
Cardiovascular Diseases, End Stage Renal Disease, Kidney Transplantation, Dialysis Related Complication
Interventions
No screening, Regular Screening
Other
Lead sponsor
University of British Columbia
Other
Eligibility
18 Years and older
Enrollment
3,306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
2
States / cities
Tucson, Arizona • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Sep 25, 2026, 4:54 AM EDT
Terminated No phase listed Observational

The Epidemiology of Bleeding and Clotting in Patients Undergoing Heart Transplantation, Coronary Artery Bypass Graft Surgery,or Implantation of Left Ventricular Assist Devices

NCT01481012
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
13
States / cities
Birmingham, Alabama • San Diego, California • Oak Lawn, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2011 · Synced Sep 25, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Randomized Study of Organ Care System Cardiac for Preservation of Donated Hearts for Eventual Transplantation

NCT00855712
View directory record Official record
Conditions
Heart Failure
Interventions
Organ Care System, Cold Cardioplegia Solution
Device
Lead sponsor
TransMedics
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
7
States / cities
Los Angeles, California • Indianapolis, Indiana • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Sep 25, 2026, 4:54 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

HEARTBiT: Multi-Marker Blood Test for Acute Cardiac Transplant Rejection

NCT03575910
View directory record Official record
Conditions
Heart Transplant Failure and Rejection, Heart Failure, Heart Diseases, Heart Failure，Congestive, Transplant; Failure, Heart, Transplant Failure
Interventions
Not listed
Lead sponsor
University of British Columbia
Other
Eligibility
19 Years and older
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 25, 2026, 4:54 AM EDT
Completed No phase listed Observational

Effectiveness of NephroCheckTM Test to Predict Acute Kidney Injury Following Advanced Cardiac Replacement Therapies

NCT02827448
View directory record Official record
Conditions
Acute Kidney Injury, Heart Failure
Interventions
Not listed
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Sep 25, 2026, 4:54 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Seeking Objectivity in Allocation of Advanced Heart Failure (SOCIAL HF) Therapies Trial

NCT05390411
View directory record Official record
Conditions
Implementation Science, Heart Transplant, Decision Making
Interventions
SOCIAL HF
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
1,463 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 25, 2026, 4:54 AM EDT
Completed No phase listed Observational

Shear Wave Elastography

NCT04493346
View directory record Official record
Conditions
Heart Failure, Transplant; Failure, Heart, Decompensated Heart Failure, Fibrosis, Liver, Cirrhosis, Liver
Interventions
Not listed
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Sep 25, 2026, 4:54 AM EDT
Not listed No phase listed Observational

NCAMR-CAMR Allosure Study

NCT04217343
View directory record Official record
Conditions
Transplant Failure
Interventions
Allosure/Allomap/Cytokines testing
Diagnostic Test
Lead sponsor
Tampa General Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Aug 21, 2022 · Synced Sep 25, 2026, 4:54 AM EDT
Completed No phase listed Observational

SUSTAIN-IT: Sustaining Quality of Life of the Aged: Heart Transplant or Mechanical Support?

NCT02568930
View directory record Official record
Conditions
Heart Failure
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
60 Years to 80 Years
Enrollment
694 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
13
States / cities
Birmingham, Alabama • Orlando, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Sep 25, 2026, 4:54 AM EDT
Terminated Phase 2 Interventional Results available

Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC

NCT00338455
View directory record Official record
Conditions
Congestive Heart Failure, Cardiac Transplantation, Renal Insufficiency, Renal Failure
Interventions
Natrecor (nesiritide)+Standard Care+dobutamine or milrinone, Placebo+Standard Care+dobutamine or milrinone
Drug
Lead sponsor
Scios, Inc.
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
14
States / cities
Stanford, California • Tampa, Florida • Chicago, Illinois + 11 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2014 · Synced Sep 25, 2026, 4:54 AM EDT
Completed Phase 2 Interventional

VentrAssistTM LVAD as a Bridge to Cardiac Transplantation - Feasibility Trial

NCT00490347
View directory record Official record
Conditions
End-Stage Heart Failure, Cardiomyopathies
Interventions
VentrAssist Left Ventricular Assist Device
Device
Lead sponsor
Ventracor
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
5
States / cities
Baltimore, Maryland • Minneapolis, Minnesota • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 16, 2008 · Synced Sep 25, 2026, 4:54 AM EDT
Completed Phase 4 Interventional Results available

Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients

NCT00369382
View directory record Official record
Conditions
Graft Rejection, Kidney Failure
Interventions
cyclosporine or tacrolimus, sirolimus
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
8
States / cities
Tampa, Florida • Rochester, Minnesota • New York, New York + 4 more
Source: ClinicalTrials.gov public record
Updated May 29, 2011 · Synced Sep 25, 2026, 4:54 AM EDT
Terminated Phase 2 Interventional Results available

Bone Marrow Cell Transplantation to Improve Heart Function in Individuals With End-Stage Heart Failure

NCT00383630
View directory record Official record
Conditions
Heart Failure, Congestive
Interventions
Intramyocardial injection of bone marrow mononuclear cells, Intramyocardial injection of CD34+ selected bone marrow mononuclear cells, LVAD alone
Biological · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
7
States / cities
Oak Lawn, Illinois • Louisville, Kentucky • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2019 · Synced Sep 25, 2026, 4:54 AM EDT
Withdrawn Not applicable Interventional

Tunneled Pleural Catheters for Refractory Effusions Attributed to Congestive Heart Failure (TREAT-CHF) Trial

NCT03696524
View directory record Official record
Conditions
Pleural Effusions, Chronic, Congestive Heart Failure, Shortness of Breath
Interventions
tunneled pleural catheter
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 4, 2023 · Synced Sep 25, 2026, 4:54 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Impella Reverse Remodeling in End-Stage Heart Failure

NCT06800716
View directory record Official record
Conditions
Heart Failure, Cardiomyopathy
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 25, 2026, 4:54 AM EDT
Terminated Not applicable Interventional

Levacor™ Ventricular Assist Device (VAD) Bridge to Transplant Study

NCT01001793
View directory record Official record
Conditions
Refractory Heart Failure
Interventions
Levacor Ventricular Assist Device
Device
Lead sponsor
World Heart Corporation
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
6
States / cities
Tampa, Florida • Louisville, Kentucky • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2011 · Synced Sep 25, 2026, 4:54 AM EDT
Completed No phase listed Observational

The Use of Aging Biomarkers to Predict Adverse Outcomes After Cardiac Surgery

NCT02496234
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Not listed
Lead sponsor
Sapere Bio
Industry
Eligibility
50 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Sep 25, 2026, 4:54 AM EDT
Completed Phase 3 Interventional

Prevention of Autogenous Vein Graft Failure in Coronary Artery Bypass Procedures

NCT00042081
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
CGT003 (E2F Duplex Decoy)
Drug
Lead sponsor
Anesiva, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
154
States / cities
Birmingham, Alabama • Daly City, California • Los Angeles, California + 89 more
Source: ClinicalTrials.gov public record
Updated May 4, 2006 · Synced Sep 25, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Safety and Effectiveness of NRP for DCD Heart Transplantation

NCT04626284
View directory record Official record
Conditions
Heart Transplant Failure, Determination of Death, Outcomes Research, Death
Interventions
Heart Transplantation
Procedure
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 25, 2026, 4:54 AM EDT
Terminated Not applicable Interventional

Clinical Trial to Evaluate the the ReliantHeart HeartAssist 5® VAD System in Patients Awaiting Heart Transplantation

NCT02205411
View directory record Official record
Conditions
Heart Failure, Cardiac Failure, Congestive Heart Failure, Heart Failure, Left-sided
Interventions
HeartAssist 5® VAD System, Control VAD
Device
Lead sponsor
ReliantHeart Inc.
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
14
States / cities
San Francisco, California • Stanford, California • Coral Gables, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Sep 25, 2026, 4:54 AM EDT
Not listed Phase 1 Interventional

Study of Anginera in Adults With a Left Ventricular Assist Device (LVAD) as Bridge to Transplant

NCT00364598
View directory record Official record
Conditions
Heart Failure
Interventions
Anginera, a human tissue replacement therapy
Drug
Lead sponsor
Theregen, Inc.
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
3
States / cities
New Haven, Connecticut • Baltimore, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2009 · Synced Sep 25, 2026, 4:54 AM EDT
Terminated Not applicable Interventional

Evaluation of the Safety and Effectiveness of the DuraHeart™ LVAS

NCT00710567
View directory record Official record
Conditions
Heart Failure
Interventions
DuraHeart Left Ventricular Assist System (LVAS)
Device
Lead sponsor
Terumo Heart Inc.
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2018
U.S. locations
25
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 20 more
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Sep 25, 2026, 4:54 AM EDT
Terminated Phase 3 Interventional

Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart Transplantation

NCT03341156
View directory record Official record
Conditions
Heart Disease End Stage, Heart Failure，Congestive
Interventions
Kcentra, Frozen Plasma Product, Human
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
3
States / cities
Baltimore, Maryland • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Sep 25, 2026, 4:54 AM EDT