Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Jul 23, 2026, 4:04 AM EDT

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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Conditions
Amputation, Amputation, Traumatic, Amputation, Congenital, Prosthesis User, Upper Limb Amputation Below Elbow (Injury), Amputation; Traumatic, Arm: Forearm, Between Elbow and Wrist
Interventions
Experimental socket with 4 untargeted channels active, Experimental socket with 8 untargeted channels active, Experimental socket with up to 16 untargeted channels active, Experimental socket with 8 targeted channels active, Coapt EMG Cuff
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Chicago, Illinois • Holliston, Massachusetts
Completed Early Phase 1 Interventional Accepts healthy volunteers

EMG-Based Hand-Wrist Control: Study B Mirrored

NCT04692571
Conditions
Amputation, Amputation; Traumatic, Hand, Amputation, Congenital, Prosthesis User
Interventions
PSICON Measurement Apparatus
Device
Lead sponsor
Liberating Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Holliston, Massachusetts • Worcester, Massachusetts
Conditions
Amputation, Traumatic
Interventions
IMES
Device
Lead sponsor
The Alfred E. Mann Foundation for Scientific Research
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Transradial Amputation
Interventions
Alpha P Control, Beta P Experimental
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 89 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Completed Not applicable Interventional

SoftHand Comparison Study

NCT05328934
Conditions
Upper Extremity Injury, Upper Extremity Deformities, Congenital, Amputation, Traumatic, Amputation, Congenital
Interventions
SoftHand Pro, Ossur i-Limb
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Tempe, Arizona • Rochester, Minnesota
Conditions
Amputation, Traumatic, Limb Defect
Interventions
SoftHand Pro with CUFF force feedback device
Device
Lead sponsor
Kristin Zhao, PhD
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Amputation; Traumatic, Hand, and Wrist, Amputation; Traumatic, Hand, at Wrist Level
Interventions
Compare control of multifunction transradial prosthesis, Perform TMR surgery and evaluate transradial TMR pattern recognition control of multifunctional prostheses.
Device · Procedure
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
3
States / cities
Chicago, Illinois • Bethesda, Maryland • Fort Sam Houston, Texas
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices

NCT06420687
Conditions
Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
Interventions
Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF, Experimental prosthesis - Wrist rotation + Multi DOF hand, Experimental prosthesis - Wrist rotation + wrist flexion + Multi DOF hand
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Amputation
Interventions
eADAPT training, Conventional training
Other
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Upper Limb Amputation at the Hand, Upper Limb Amputation at the Wrist, Amputation, Amputation; Traumatic, Limb
Interventions
Commercially available device, Non FDA registered device
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 95 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers Results available

Functional Performance of Voluntary Opening and Closing Body Powered Prostheses

NCT02136238
Conditions
Upper Limb Amputation
Interventions
Hosmer 5XA voluntary opening hook, TRS Grip 3 voluntary closing hook
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 85 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Amputation, Amputation; Traumatic, Hand
Interventions
Myoelectric Implantable Recording Array (MIRA)
Device
Lead sponsor
Boninger, Michael, MD
Other
Eligibility
22 Years to 70 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Upper Limb Amputation Below Elbow
Interventions
Cutaneous Prosthesis Control System
Device
Lead sponsor
Phantom Neuro Inc.
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Buffalo, New York • Austin, Texas
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Prosthetic Arms for Amputee: A Better Fit and More Functionality

NCT05990062
Conditions
Amputation, Surgical
Interventions
K-Socket-Harness
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Amputation, Prosthesis Use
Interventions
Training with PRC, Training with DC, PRC Device use in community and home, DC Device use in community and home
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Austin, Texas • Richmond, Virginia