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Showing 1–24 of 1,814 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Trauma and Stress Related Disorders Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Mind-Body Skills Groups for the Treatment of War Zone Stress in Military and Veteran Populations

NCT01093053
View directory record Official record
Conditions
Stress Disorders, Post Traumatic, Brain Injuries, Depressive Disorder, Anxiety Disorders, Anger
Interventions
Mind-Body Skills Groups, Standard Treatment
Behavioral · Other
Lead sponsor
The Center for Mind-Body Medicine
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 28, 2014 · Synced Sep 19, 2026, 4:53 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Synergy Between Patient and Clinician: Using a Trauma-Informed Care Plan

NCT06330753
View directory record Official record
Conditions
Trauma and Stressor Related Disorders, Violence, Structural, Violence, Domestic, Violence, Sexual
Interventions
Trauma-informed Care Plan-
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Sep 19, 2026, 4:53 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Flash Open Trial With Therapists In Training

NCT03271437
View directory record Official record
Conditions
Trauma, Psychological
Interventions
PC-based Flash, EMDR-based Flash
Behavioral
Lead sponsor
Trauma Institute & Child Trauma Institute
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Northampton, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 6, 2017 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Phase 2 Interventional Results available

D-cycloserine Adjunctive Treatment for Posttraumatic Stress Disorder (PTSD) in Adolescents

NCT01157429
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
D-cycloserine, Placebo pill, CBT
Drug · Behavioral
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
13 Years to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Evaluating the Feasibility of RESCUE: An Adjunctive HAI-Based Intervention for Veterans With PTSD

NCT03504722
View directory record Official record
Conditions
PTSD
Interventions
RESCUE, Prolonged Exposure
Behavioral
Lead sponsor
Charleston Research Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 21, 2020 · Synced Sep 19, 2026, 4:53 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Trauma Center-Based Intervention for Adolescent Traumatic Injury Survivors

NCT05086757
View directory record Official record
Conditions
Traumatic Injury, Technology, Posttraumatic Stress Disorder, Adolescents
Interventions
TRRP, Enhanced Usual Care
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Phase 2Phase 3 Interventional

Modification of Cognitive Processing Therapy (CPT-C) for PTSD and Alcohol Dependence

NCT00639288
View directory record Official record
Conditions
Alcohol Dependence, PTSD
Interventions
modified CPT-C
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 20, 2016 · Synced Sep 19, 2026, 4:53 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

AI to Support Mental Health Case Management Providers

NCT06280170
View directory record Official record
Conditions
Depressive Disorder, Anxiety Disorders, Substance Use Disorders, Post Traumatic Stress Disorder
Interventions
Artificial Intelligence platform for case managers
Other
Lead sponsor
Eleos Health
Industry
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Alton, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Sep 19, 2026, 4:53 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Atomoxetine and Executive Function in PTSD

NCT06573970
View directory record Official record
Conditions
Posttraumatic Stress Disorder With Attention Defic
Interventions
Atomoxetine, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 19, 2026, 4:53 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

K08 VR Fear Conditioning

NCT07216222
View directory record Official record
Conditions
Anxiety and Fear, PTSD, Veteran
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Phase 2 Interventional Results available

Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder

NCT01211405
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Low dose MDMA-assisted therapy, Medium dose MDMA-assisted therapy, Full dose MDMA-assisted therapy, Therapy
Drug · Behavioral
Lead sponsor
Resilient Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Treatment for Veterans With Military Sexual Trauma

NCT00371644
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Depressive Symptoms, Anxiety Symptoms, Quality of Life
Interventions
Cognitive Processing Therapy, Present-Centered Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2015 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional Results available

Yoga and Physical Activity for Veterans

NCT03509909
View directory record Official record
Conditions
PTSD
Interventions
Hatha yoga, Supportive physical activity
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wakȟáŋyeža (Little Holy One)

NCT04201184
View directory record Official record
Conditions
Suicide, Trauma, Psychological, Parenting
Interventions
Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules, Active nutrition control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Poplar, Montana
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women

NCT06646692
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Anxiety, Depression - Major Depressive Disorder
Interventions
Mindful Self Compassion, Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Female only
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional

Effects of Narrative Writing Duration and Post-writing Processing Instructions on PTSD

NCT01773811
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Narrative Writing: Trauma-Assigned, Narrative Writing: Trauma-Spontaneous
Behavioral
Lead sponsor
University of Mississippi, Oxford
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
University, Mississippi
Source: ClinicalTrials.gov public record
Updated May 14, 2014 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Phase 4 Interventional

Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD)

NCT00203463
View directory record Official record
Conditions
PTSD
Interventions
topiramate
Drug
Lead sponsor
Tuscaloosa Research & Education Advancement Corporation
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 28, 2009 · Synced Sep 19, 2026, 4:53 AM EDT
Not listed Not applicable Interventional

Stress-Reducing Interventions in HIV+ Patients: Pilot

NCT00599599
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, HIV Infections
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
Kent State University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
2
States / cities
Akron, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2009 · Synced Sep 19, 2026, 4:53 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

PHF Problematic Sexual Behavior of Youth Family Engagement

NCT04902287
View directory record Official record
Conditions
Trauma, Sexual
Interventions
Training Intervention for the Engagement of Families (TIES)
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
7 Years to 12 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 25, 2022 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Relief of Symptoms of Post-traumatic Stress for Victims of Gun Violence

NCT03916614
View directory record Official record
Conditions
PTSD, Stress, Psychological, Gunshot Wound
Interventions
Screening Tool for Relief of Trauma (START), standard of care
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 13, 2022 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Phase 3 Interventional

Optimal Treatment Strategies for Sexually Abused Children

NCT00073684
View directory record Official record
Conditions
Child Abuse, Sexual
Interventions
Trauma focused cognitive behavioral therapy (TF-CBT), Brief abuse-focused treatment, Brief coping skills treatment, Extended abuse-focused treatment, Extended coping skills treatment
Behavioral
Lead sponsor
Rowan University
Other
Eligibility
4 Years to 11 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Stratford, New Jersey
Source: ClinicalTrials.gov public record
Updated May 7, 2014 · Synced Sep 19, 2026, 4:53 AM EDT
Recruiting Phase 2 Interventional

Long-Term Outcomes Following HBOT

NCT07732374
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Breathing on Cognitive Performance and Stress

NCT06986135
View directory record Official record
Conditions
Stress, Acute Stress Reaction, Breathing Techniques, Cognitive Performance
Interventions
Box Breathing, Prolonged Exhalation, Normal Breathing
Other
Lead sponsor
Texas State University
Other
Eligibility
18 Years to 39 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 19, 2026, 4:53 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Behavioral Treatments for Acute Stress Disorder In Firefighters

NCT00183508
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Cognitive behavioral therapy, Psychoeducation
Behavioral
Lead sponsor
Boston University
Other
Eligibility
21 Years to 65 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 13, 2015 · Synced Sep 19, 2026, 4:53 AM EDT