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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Trauma and Stress-related Disorders Clear all
Completed Not applicable Interventional

The Family of Heroes: an Evaluation of an Online Educational Tool

NCT01554839
View directory record Official record
Conditions
Post Traumatic Stress Disorder, PTSD
Interventions
"Family of Heroes", Baseline and Follow up Surveys
Behavioral
Lead sponsor
Department of Veterans Affairs, New Jersey
Federal
Eligibility
18 Years and older
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Lyons, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 9, 2015 · Synced Jun 10, 2026, 2:12 PM EDT
Terminated Not applicable Interventional Results available

Tapering Off Antidepressants

NCT02661828
View directory record Official record
Conditions
Major Depressive Disorder, Anxiety Disorder, Obsessive Compulsive Disorder, Post-Traumatic Stress Disorder
Interventions
Two-Week Antidepressant Taper Regimen, One-Week Antidepressant Taper Regimen
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

PTSD Treatment for Incarcerated Men and Women: AV

NCT07283757
View directory record Official record
Conditions
PTSD
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Increasing Engagement in Evidence-Based PTSD Therapy for Primary Care Veterans

NCT01984515
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Referral Management System
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2015 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurobiological Correlates of Post Traumatic Stress Disorder (PTSD) During Rapid Eye Movement (REM) Sleep

NCT00871650
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Sleep data recording, PET scan - waking, PET scan - REM Sleep
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Chemical Receptor Effects in Patients With Panic Disorder and Post-Traumatic Stress Disorder

NCT00025974
View directory record Official record
Conditions
Panic Disorder, Posttraumatic Stress Disorder, Major Depressive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 50 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 10, 2026, 2:12 PM EDT
Not listed No phase listed Observational

Advanced MRI In Acute Military TBI

NCT01313130
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 9, 2014 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Phase 2 Interventional

Evaluating a Website for Parents of Injured Children

NCT00974467
View directory record Official record
Conditions
Acute Post-Traumatic Stress Disorder
Interventions
After The Injury website, Control
Behavioral · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2015 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)

NCT07060144
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Pregnancy
Interventions
Regular CPT, Massed CPT
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 46 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Can Service Dogs Improve Activity and Quality of Life in Veterans With PTSD?

NCT02039843
View directory record Official record
Conditions
Post Traumatic Stress Disorders
Interventions
Emotional Support Dogs, Service Dogs
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
287 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
4
States / cities
Decatur, Georgia • Iowa City, Iowa • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional

Brief Integrative Therapy for Post-Traumatic Stress Disorder

NCT00047684
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Brief Integrative Therapy
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2002
U.S. locations
1
States / cities
White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Sep 9, 2013 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional

Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD

NCT02290847
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Cognitive Processing Therapy (cognitive only version; CPT-C)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 3, 2020 · Synced Jun 10, 2026, 2:12 PM EDT
Not listed Not applicable Interventional

Delivery of Self Training and Education for Stressful Situations-Telephone Version

NCT01502449
View directory record Official record
Conditions
PTSD
Interventions
DESTRESS-T, Optimized Usual Care (OUC)
Behavioral · Other
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 65 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Columbus, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 11, 2012 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional

TMS-fNIRS Personalized Dosing

NCT05916417
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
TMS-fNIRS over the dl-PFC
Device
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Suspended Not applicable Interventional

Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression

NCT01794559
View directory record Official record
Conditions
Depressive Disorder
Interventions
PEER Interactive Report
Device
Lead sponsor
MYnd Analytics
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,922 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Identifying Biomarkers That Distinguish PTSD and mTBI Using Advanced Magnetic Resonance Spectroscopy

NCT02927288
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Brain Injuries
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional Results available

Breathing Meditation Intervention for Post Traumatic Stress Disorder

NCT02366403
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
SKY meditation, CPT-C
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 11, 2022 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Imaging the Neuroimmune System in PTSD

NCT04236986
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Lipopolysaccharide
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Phase 3 Interventional Results available

Estrogen and Fear in PTSD

NCT04192266
View directory record Official record
Conditions
PTSD
Interventions
Estradiol, Placebo oral tablet, Prolonged Exposure (PE) therapy
Drug · Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Completed Not applicable Interventional

Group vs. Individual Cognitive Processing Therapy for Combat-related PTSD

NCT02173561
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Group Cognitive Processing Therapy-Cognitive Only, Individual Cognitive Processing Therapy-Cognitive Only
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2017 · Synced Jun 10, 2026, 2:12 PM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia

NCT06644573
View directory record Official record
Conditions
Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder, REM Sleep Measurement, Insomnia, Insomnia Related to Specified Disorder, Insomnia Due to Other Mental Disorder, Insomnia Comorbid to Psychiatric Disorder, Insomnia Due to Anxiety and Fear, Insomnia Related to Another Mental Condition, Insomnia Disorders, Idiopathic Hypersomnia, Sleep Disorders, Circadian Rhythm, Post Trauma Nightmares, PTSD - Post Traumatic Stress Disorder, Sleep Quality, Anesthesia, Anxiety, Depression, Mental Health, Alzheimer Disease or Associated Disorder, Parkinsons, Circadian Rhythm, Circadian Dysregulation, PTSD, Post-Traumatic, Post-Traumatic Stress Disorder Complex, Military Combat Stress Reaction, Sleep, Military Activity, Veterans, Shift Work Sleep Disorder, Menopause Related Conditions, Pain, Cancer Pain, Athletes
Interventions
PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca, Continuous EEG Monitoring
Procedure · Drug · Device
Lead sponsor
Nyree Penn
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated May 27, 2025 · Synced Jun 10, 2026, 2:12 PM EDT
Active, not recruiting Phase 2 Interventional

Psilocybin for the Treatment of Veterans With Post-Traumatic Stress Disorder

NCT05554094
View directory record Official record
Conditions
PTSD, Stress Disorders, Traumatic, Stress Disorders, Post-Traumatic, Trauma and Stressor Related Disorders, Mental Disorder
Interventions
Psilocybin
Drug
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jun 10, 2026, 2:12 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Creative Arts Program to Reduce Burnout in Healthcare Professionals

NCT04276922
View directory record Official record
Conditions
Burn-Out Syndrome, Post-Traumatic Stress Disorder, Depression, Anxiety
Interventions
Visual Arts, Music, Dance/Movement, Writing/Poetry, Control
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 85 Years
Enrollment
195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 15, 2024 · Synced Jun 10, 2026, 2:12 PM EDT
Completed No phase listed Observational

The Stress-Hormone System in Alcohol-Dependent Subjects

NCT00536146
View directory record Official record
Conditions
Alcoholism
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
21 Years to 60 Years · Male only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 10, 2026, 2:12 PM EDT