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Showing 361–384 of 1,791 matching trials from the live ClinicalTrials.gov search.
Conditions
PTSD, Depression
Interventions
Self-management therapy; Psychoeducational group therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2002
U.S. locations
1
States / cities
Houston, Texas
Conditions
PTSD
Interventions
Mobile Acoustic startle Reflex monitoring System (MARS)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Male only
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Behavioral Health for Caregivers and Children After Pediatric Injury

NCT06856057
Conditions
Quality of Life, PTSD, Depression Not Otherwise Specified, Child Externalizing Behavior
Interventions
Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
348 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
4
States / cities
Los Angeles, California • Lexington, Kentucky • Ann Arbor, Michigan + 1 more
Conditions
Posttraumatic Stress Disorder
Interventions
D-Cycloserine, Placebo
Drug · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

Psychophysiologic Predictors of Post-deployment Mental Health Outcomes

NCT00838006
Conditions
Post-traumatic Stress Disorder
Interventions
heart rate variability biofeedback, Cognitive bias modification training, Sham Comparator
Device
Lead sponsor
Biomedical Research Foundation
Other
Eligibility
18 Years to 60 Years
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Blackstone, Virginia
Conditions
Posttraumatic Stress Disorder
Interventions
Lifespan Integration Therapy, Lifespan Integration- Control
Behavioral
Lead sponsor
Argosy University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Post Traumatic Stress Disorder
Interventions
CPT Skills, Cognitive Processing Therapy, Present Centered Therapy, Shared Decision Making, Measurement Based Care
Behavioral
Lead sponsor
United States Department of Defense
Federal
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
4
States / cities
Phoenix, Arizona • New Orleans, Louisiana • Charleston, South Carolina + 1 more
Conditions
Posttraumatic Neuroses
Interventions
Brief Family Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Implementation of Prolonged Exposure in the Military

NCT02982538
Conditions
PTSD
Interventions
Extended Training in Prolonged Exposure Therapy for PTSD, Standard Training in Prolonged Exposure Therapy for PTSD
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
3
States / cities
Colorado Springs, Colorado • Fort Campbell North, Kentucky • El Paso, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility Study for Abused Chinese Immigrant Women

NCT05011552
Conditions
Intimate Partner Violence, Depression, Anxiety, PTSD
Interventions
Self-Compassion, Health, and Empowerment (SHE), The Control Condition
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Austin, Texas
Conditions
Posttraumatic Stress Disorder, PTSD
Interventions
Cognitive Processing Therapy (cognitive only version; CPT-C)
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Antonio, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD

NCT03283163
Conditions
Chronic Musculoskeletal Pain, Posttraumatic Stress Disorder (PTSD), Mild or Moderate Traumatic Brain Injury
Interventions
Exercise Testing and Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Effectiveness of Trauma Management Therapy and Prolonged Exposure Therapy

NCT04549493
Conditions
PTSD
Interventions
Exposure Therapy
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 64 Years
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Mood Lability, PTSD, Anxiety
Interventions
FamilyLive, Standard Mental Health Treatment
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
5 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Posttraumatic Stress Disorder
Interventions
DBS of the Basolateral Nucleus of the Amygdala, Medtronic Activa PC DBS of the Basolateral Nucleus of the Amygdala
Procedure · Device
Lead sponsor
VA Greater Los Angeles Healthcare System
Federal
Eligibility
25 Years to 70 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

NCT07288593
Conditions
Nightmare, Insomnia, PTSD, TBI, Sleep Disorder (Disorder), REM Behavior Disorder
Interventions
NightWare smartwatch configured to detect physiological signs of sympathetic activation during sleep, such as heart-rate spikes and movement patterns., Sham (No Treatment)
Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 62 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Bethesda, Maryland • Minneapolis, Minnesota
Conditions
PTSD, Panic Attacks
Interventions
Multiple Channel Exposure Therapy- Veterans
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 64 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

Increasing Treatment Efficacy Using SMART Methods for Personalizing Care

NCT04642898
Conditions
Anxiety Disorders, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
Interventions
Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
Behavioral
Lead sponsor
Shannon E. Sauer-Zavala
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Not applicable Interventional

Chaplain Family Project Trial

NCT03702634
Conditions
Anxiety, PTSD, Depression, Communication, Satisfaction
Interventions
Spiritual Care Assessment and Intervention (SCAI) framework
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
2
States / cities
Indianapolis, Indiana
Conditions
HIV Infection
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Completed No phase listed Observational Results available

Regional Anesthesia Military Battlefield Pain Outcomes Study

NCT00431847
Conditions
Anxiety Disorders, Complex Regional Pain Syndrome Type II, Depressive Disorders, Post-Traumatic Stress Disorder, Substance Abuse
Interventions
Regional Anesthesia, Standard Pain Management Protocol
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
3
States / cities
Bethesda, Maryland • Philadelphia, Pennsylvania • Fort Sam Houston, Texas
Completed Not applicable Interventional Results available

Improving Obesity Self-Care Among Mentally Ill Veterans

NCT02642536
Conditions
Anxiety, Depression, PTSD, Obesity
Interventions
MH MOVE, Enhanced Usual Care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional

Acupressure and Stress Resilience

NCT01614444
Conditions
Post-traumatic Stress Disorder (PTSD), Mild Traumatic Brain Injury (mTBI)
Interventions
Active Acupressure Treatment, Placebo Acupressure Treatment
Other
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Conditions
PTSD
Interventions
TNX-102 SL 5.6 mg
Drug
Lead sponsor
Tonix Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
16
States / cities
Little Rock, Arkansas • Beverly Hills, California • Oceanside, California + 13 more