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ClinicalTrials.gov public records Last synced Oct 14, 2026, 10:41 PM EDT

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Showing 385–408 of 1,791 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Trauma and Stressor Related Disorder Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

RCT for Innovating Stress-related eHealth

NCT05305235
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Sexual Assault, Pain
Interventions
RISE Guide, Relaxation Control
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Pain Management Using Mobile Technology in Veterans With PTSD and TBI

NCT02237885
View directory record Official record
Conditions
Chronic Pain, Posttraumatic Stress Disorders, Traumatic Brain Injury
Interventions
NeuroSky MindWave Mobile
Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 18, 2020 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Telephone Delivery of Cognitively Augmented Behavioral Activation (CABA)

NCT04200976
View directory record Official record
Conditions
Traumatic Brain Injury, Posttraumatic Stress Disorder
Interventions
Tele-CABA, Usual Care
Behavioral
Lead sponsor
Portland VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 14, 2026, 10:41 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neurobiological Correlates of Post Traumatic Stress Disorder (PTSD) During Rapid Eye Movement (REM) Sleep

NCT00871650
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Sleep data recording, PET scan - waking, PET scan - REM Sleep
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2013 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Adaptation of Written Exposure Therapy in Substance Treatment

NCT07108608
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Use Disorders
Interventions
Written Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
Potomac Health Foundations
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 14, 2026, 10:41 PM EDT
Terminated Phase 4 Interventional Results available

Antidepressant Response in Older Adults With Comorbid PTSD and MDD

NCT04697693
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Major Depressive Disorder
Interventions
Escitalopram, Duloxetine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
60 Years to 105 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 14, 2026, 10:41 PM EDT
Recruiting Phase 2 Interventional

Mindfulness-based Psilocybin Therapy for PTSD

NCT07104916
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Depression - Major Depressive Disorder
Interventions
Psilocybin + MBCT therapy, Active Comparator: Psilocybin with Support Only
Combination Product
Lead sponsor
Anthony P King
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional Results available

Mobile Intervention for Veterans With PTSD and Anger

NCT03733028
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Anger
Interventions
Mobile Intervention for Reducing Anger (MIRA), Mindfulness Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Mobile Phone App for Veterans With PTSD

NCT03199742
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Veterans
Interventions
Personalized App Coaching, Active Comparator
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Menlo Park, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fuerte Program for Newcomer Immigrant Youth

NCT04156373
View directory record Official record
Conditions
Trauma, Psychological, Mental Disorder in Adolescence, Adolescent - Emotional Problem
Interventions
Fuerte
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
12 Years and older
Enrollment
321 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional Results available

HIRREM Developmental Study

NCT02709369
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes, Headache, Traumatic Brain Injury, Post Concussion Symptoms
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
11 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 24, 2019 · Synced Oct 14, 2026, 10:41 PM EDT
Not listed Phase 1Phase 2 Interventional

Thermal Clinic Treatment in Gulf War Illness

NCT02293291
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Lithium Water
Dietary Supplement
Lead sponsor
American Society Of Thermalism And Climatology Inc
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Oct 14, 2026, 10:41 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Transcendental Meditation in Veterans and First Responders With PTSD

NCT05645042
View directory record Official record
Conditions
PTSD
Interventions
Transcendental Meditation (TM), Present Centered Therapy (PCT)
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
5
States / cities
La Jolla, California • Los Angeles, California • Palo Alto, California + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms

NCT00475241
View directory record Official record
Conditions
Combat Disorders, Posttraumatic Stress Disorder
Interventions
Prolonged Exposure therapy for PTSD, Present centered therapy for PTSD
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Non Invasive Brain Stimulation for PTSD

NCT02442843
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Active tDCS, Sham tDCS
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 88 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional

IPT-A for Adolescents With PTSD Symptoms

NCT03795818
View directory record Official record
Conditions
PTSD
Interventions
Interpersonal Psychotherapy for Adolescents
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
13 Years to 18 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2024 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma

NCT00208182
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Risperidone
Drug
Lead sponsor
Creighton University
Other
Eligibility
19 Years to 64 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2004
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 10, 2006 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Exposure, Relaxation, & Rescripting Therapy-Child

NCT02184026
View directory record Official record
Conditions
Post Trauma Nightmares, Traumatic Stress
Interventions
Exposure, Relaxation, & Rescripting Therapy-Child
Behavioral
Lead sponsor
University of Montana
Other
Eligibility
8 Years to 13 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Jun 20, 2016 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Repeated Virtual Reality Training on Markers of Stress

NCT07770880
View directory record Official record
Conditions
Stress, Acute Stress Reaction, Virtual Reality, Active Shooter, Law Enforcement Training
Interventions
Active Shooter, Target Practice
Other
Lead sponsor
Texas State University
Other
Eligibility
18 Years to 39 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 14, 2026, 10:41 PM EDT
Recruiting Phase 2 Interventional

Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD

NCT06902974
View directory record Official record
Conditions
Post Traumatic Stress Disorder, PTSD
Interventions
Psilocybin 25 mg
Drug
Lead sponsor
Sunstone Medical
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Outcomes After Spinal Cord Injury (OASIS)

NCT03624218
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Spinal Cord Injuries
Interventions
Prolonged Exposure Therapy
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 23, 2026 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Treating Post Traumatic Stress Disorder in Children Exposed to Domestic Violence

NCT00183326
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Anxiety, Depression
Interventions
Trauma-focused cognitive behavioral therapy (TF-CBT), Child-centered supportive therapy (CCT)
Behavioral
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
7 Years to 14 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2015
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Not applicable Interventional Results available

A Placebo-Controlled Trial of D-Cycloserine and Exposure Therapy for Combat-PTSD

NCT00371176
View directory record Official record
Conditions
Combat Disorders, Stress Disorders, Post-Traumatic
Interventions
Exposure therapy, D-Cycloserine, Placebo pill
Behavioral · Drug · Other
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Oct 14, 2026, 10:41 PM EDT
Completed Phase 2 Interventional Results available

Novel Therapeutics in Posttraumatic Stress Disorder (PTSD): A Randomized Clinical Trial of Mifepristone

NCT01739335
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Mifepristone Oral Tablet [Korlym], Placebo Oral Tablet
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years · Male only
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
5
States / cities
San Diego, California • Albuquerque, New Mexico • The Bronx, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Oct 14, 2026, 10:41 PM EDT