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ClinicalTrials.gov public records Last synced Oct 15, 2026, 8:47 AM EDT

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Showing 505–528 of 1,791 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Trauma and Stressor Related Disorder Clear all
Terminated No phase listed Observational Accepts healthy volunteers

Using Wearable Technology to Detect Symptoms of Posttraumatic Stress Disorder

NCT05534100
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Biostrap EVO Wristband
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Oct 15, 2026, 8:47 AM EDT
Recruiting Not applicable Interventional

Advancing Couple and Family Alcohol Treatment Through Patient-Oriented Research and Mentorship

NCT05786157
View directory record Official record
Conditions
Alcohol Use Disorder, Posttraumatic Stress Disorder, Couples
Interventions
Alcohol Administration
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years and older
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Phase 2 Interventional

MDMA for AUD/PTSD Comorbidity

NCT05943665
View directory record Official record
Conditions
Alcohol Use Disorder, Post Traumatic Stress Disorder
Interventions
MDMA
Drug
Lead sponsor
Carolina L Haass-Koffler
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Phase 2 Interventional

Alcohol Use Disorders (AUDs) and Post-traumatic Stress Disorder (PTSD) Treatment for Victims of Partner Violence

NCT00607412
View directory record Official record
Conditions
PTSD, Substance Use Disorders
Interventions
Integrated psychotherapy for PTSD and substance use, 12-step based supportive therapy
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 11, 2011 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional

The Impact of a School-Based, Trauma-Informed CBT Intervention for Young Women

NCT03376633
View directory record Official record
Conditions
Anxiety, Anxiety Disorders, Behavioral Symptoms, Depression, Mental Disorders, Stress Disorders, Post-Traumatic, Stress Disorders, Traumatic, Trauma and Stressor Related Disorders, Wounds and Injuries
Interventions
Working on Womanhood (WOW)
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
Female only
Enrollment
5,106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Oct 15, 2026, 8:47 AM EDT
Terminated Not applicable Interventional Results available

Neurofeedback of Amygdala Activity for Post-traumatic Stress Disorder

NCT03574974
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Experimental Feedback, Control Feedback
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Oct 15, 2026, 8:47 AM EDT
Not listed Not applicable Interventional

Effects of Games on Memory Reconsolidation and Trauma Symptoms

NCT06129435
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Trauma
Interventions
Visuospatial Task (VST), Word Association Task (WAT)
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 5, 2024 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Phase 4 Interventional Results available

Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder

NCT00120250
View directory record Official record
Conditions
Post-Traumatic Stress Disorders
Interventions
Eszopiclone
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 26, 2016 · Synced Oct 15, 2026, 8:47 AM EDT
Not yet recruiting Not applicable Interventional

Self-Help Intervention for Post 9/11 Veterans With Depression or PTSD Symptoms

NCT07202325
View directory record Official record
Conditions
Depression, Stress Disorders, Post-Traumatic
Interventions
Resilience Training for Veterans (REST-V), Usual resources
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
2
States / cities
Syracuse, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 15, 2026, 8:47 AM EDT
Not yet recruiting Not applicable Interventional

Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI

NCT07715799
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Transcranial Direct Current Stimulator, Written Exposure Therapy
Device · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 15, 2026, 8:47 AM EDT
Suspended Phase 2 Interventional Accepts healthy volunteers

Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002

NCT06816433
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Intervention D SLS-002, Intervention D Placebo
Drug
Lead sponsor
Global Coalition for Adaptive Research
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2028 – 2029
U.S. locations
9
States / cities
Miami, Florida • Atlanta, Georgia • Tripler AMC, Hawaii + 6 more
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Phase 3 Interventional Results available

Re-Engineering Systems for the Primary Care Treatment for PTSD

NCT00373698
View directory record Official record
Conditions
Stress Disorders, Posttraumatic, Depression
Interventions
Three Component Model of Collaborative Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
195 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
4
States / cities
Dallas, Texas • Temple, Texas • Waco, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2015 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Integrating Clinical Practice Guidelines for Smoking Cessation Into Mental Health Care for Veterans With Posttraumatic Stress Disorder

NCT00118534
View directory record Official record
Conditions
Mental Health, Stress Disorders, Post-Traumatic, Substance-Related Disorders, Tobacco Use Disorder
Interventions
Integrated Care for Smoking Cessation in PTSD patients, Standard of Care
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 80 Years
Enrollment
943 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
11
States / cities
Tuscaloosa, Alabama • San Diego, California • Washington D.C., District of Columbia + 8 more
Source: ClinicalTrials.gov public record
Updated May 5, 2014 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wakȟáŋyeža (Little Holy One)

NCT04201184
View directory record Official record
Conditions
Suicide, Trauma, Psychological, Parenting
Interventions
Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules, Active nutrition control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Poplar, Montana
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional

Short-Term Exposure for PTSD

NCT02874898
View directory record Official record
Conditions
Chronic Post-Traumatic Stress Disorder, Marijuana Abuse
Interventions
Brief Imaginal Exposure
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional

Therapeutic Effects of the Processing of Positive Memories Technique on Posttrauma Health

NCT06680193
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Processing of Positive Memories Technique
Behavioral
Lead sponsor
University of North Texas, Denton, TX
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Denton, Texas
Source: ClinicalTrials.gov public record
Updated Nov 8, 2024 · Synced Oct 15, 2026, 8:47 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents

NCT05893459
View directory record Official record
Conditions
Child Maltreatment, Interpersonal Relations, Victimisation, Psychopathology, Electrocardiography
Interventions
Debrief
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
13 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 16, 2024 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional Results available

Cognitive-Behavioral Conjoint Therapy (CBCT) Project

NCT02720016
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
CBCT-Home Based (CBCT-HB), CBCT-Office Based (CBCT-OB), PTSD Family Education (PFE)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional Results available

TMS for Veterans Attending a 2-week Intensive Outpatient Program for PTSD

NCT06271733
View directory record Official record
Conditions
PTSD
Interventions
TMS
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Phase 4 Interventional Results available

Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD

NCT03937713
View directory record Official record
Conditions
Complex Insomnia
Interventions
eszopiclone, Brief behavioral therapy for insomnia
Drug · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Imaging the Neuroimmune System in PTSD

NCT04236986
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Lipopolysaccharide
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional Results available

Trauma-Focused Equine-Assisted Therapy (TF-EAT) for Veterans With PTSD

NCT03068325
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
EAT-PTSD
Other
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Not applicable Interventional Results available

Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans

NCT02657317
View directory record Official record
Conditions
Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression, Opioid Use Disorder
Interventions
FORT-A, VA Treatment as Usual
Behavioral · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 72 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 15, 2026, 8:47 AM EDT
Completed Phase 1 Interventional

Multicomponent Cognitive Behavioral Therapy(CBT) for Posttraumatic Stress Disorder (PTSD) and Substance Abuse

NCT01029197
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Abuse
Interventions
CBT and exposure therapy for PTSD, Treatment as Usual
Behavioral · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 7, 2010 · Synced Oct 15, 2026, 8:47 AM EDT