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ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:55 AM EDT

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Showing 73–96 of 1,789 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Trauma and Stressor Related Disorder Clear all
Completed Not applicable Interventional

Pilot Study of PRX-03140 to Assess Safety for Use in Adult Subjects With Post Traumatic Stress Disorder

NCT01492699
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
PRX-03140
Drug
Lead sponsor
Alachua Government Services, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Oct 5, 2026, 4:55 AM EDT
Recruiting Phase 2 Interventional

Mindfulness-based Psilocybin Therapy for PTSD

NCT07104916
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Depression - Major Depressive Disorder
Interventions
Psilocybin + MBCT therapy, Active Comparator: Psilocybin with Support Only
Combination Product
Lead sponsor
Anthony P King
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional

Trial of a Novel Cognitive-Behavioral Treatment for Posttraumatic Stress and Substance Dependence

NCT02461732
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Substance Dependence
Interventions
Treatment for Integrated Posttraumatic Stress and Substance Use (TIPSS), Cognitive-Behavioral Therapy for Substance Dependence
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 10, 2017 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Mindfulness Based Cognitive Therapy (MBCT) Resiliency Program for Critical Care Nurses

NCT03132220
View directory record Official record
Conditions
Burn-Out Syndrome, Work-Related Stress Disorder
Interventions
Mindfulness-Based Cognitive Therapy, Book Club Active Control Intervention
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 9, 2019 · Synced Oct 5, 2026, 4:55 AM EDT
Completed No phase listed Observational

The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study

NCT01040988
View directory record Official record
Conditions
Depression, Anxiety, Post-traumatic Stress Disorder
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 20 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2017 · Synced Oct 5, 2026, 4:55 AM EDT
Recruiting Not applicable Interventional

Determining the Right Acupuncture for Good Recovery Over Neuropsychiatric Trauma

NCT05516862
View directory record Official record
Conditions
PTSD, Post Traumatic Stress Disorder, Acupuncture
Interventions
Dragons acupuncture, Dragons acupressure, Dragons placebo
Other
Lead sponsor
Paul Crawford
Federal
Eligibility
18 Years to 74 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional

Intensive Care Unit (ICU) Diary Project

NCT04305353
View directory record Official record
Conditions
PTSD, Post ICU Syndrome
Interventions
Diary (blank journal) plus PTSD psycho-education, PTSD psycho-education alone
Other
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Oct 5, 2026, 4:55 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Project SERVE: Post Deployment Functioning

NCT01123642
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Depressive Disorder, Alcoholism
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Aug 20, 2018 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Mobile Phone App for Veterans With PTSD

NCT03199742
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Veterans
Interventions
Personalized App Coaching, Active Comparator
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Menlo Park, California
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 5, 2026, 4:55 AM EDT
Enrolling by invitation No phase listed Observational

Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

NCT06823024
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD, Generalized Anxiety Disorder (GAD)
Interventions
Not listed
Lead sponsor
Psyrin Inc.
Industry
Eligibility
18 Years to 68 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Sunnyvale, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 5, 2026, 4:55 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

TDCS-Augmented Prolonged Exposure Therapy

NCT04327362
View directory record Official record
Conditions
Posttraumatic Stress Disorder, PTSD, Anxiety, Depression
Interventions
Transcranial Direct Current Stimulation (tDCS), Prolonged Exposure Therapy
Device · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindful Attention Training Workshop for Firefighters

NCT04909216
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Mindfulness, Firefighters, Trauma, Mental Disorders
Interventions
Mindful Attention Workshop
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional

Neural Correlates of PTSD Prevention With Mindfulness Based Stress Reduction (MBSR) in Iraqi Veterans

NCT01058031
View directory record Official record
Conditions
Stress Disorders, Posttraumatic, PTSD
Interventions
MBSR
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years · Male only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 5, 2013 · Synced Oct 5, 2026, 4:55 AM EDT
Recruiting Not applicable Interventional

Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy

NCT03755401
View directory record Official record
Conditions
PTSD
Interventions
TFPP, TAU
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 5, 2026, 4:55 AM EDT
Not yet recruiting Not applicable Interventional

EEG and Actigraphy Biomarkers of Written Exposure Therapy for Posttraumatic Stress Disorder

NCT07766798
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Written Exposure Therapy, Neutral Writing Condition
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 5, 2026, 4:55 AM EDT
Not listed No phase listed Observational

Schizophrenia and PTSD Project: Health, Interventions, and Risk/Resilience Evaluation(SAPPHIRE Study)

NCT00560677
View directory record Official record
Conditions
Schizophrenia, PTSD
Interventions
Not listed
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
18 Years to 72 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 5, 2026, 4:55 AM EDT
Completed No phase listed Observational

Effectiveness and Acceptability of Stellate Ganglion Block for Posttraumatic Stress Disorder Symptoms - Acceptability

NCT03302312
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Not listed
Lead sponsor
RTI International
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Honolulu, Hawaii • Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 30, 2018 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional

Targeting Cognition in PTSD: Pregnenolone Augmentation of SSRIs

NCT00560781
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic
Interventions
Pregnenolone or Placebo
Drug
Lead sponsor
Durham VA Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 26, 2014 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Digital Resilience Intervention for Emergency Medical Service Workers

NCT06861400
View directory record Official record
Conditions
Feasibility, Acceptability, Adoptability, Meaning Made, Adaptive Self-reflection, Recovery Activities, Recovery Experiences, Post Traumatic Stress Disorder PTSD, Anxiety, Depression
Interventions
Self-Reflective Resilience-Recovery Activity Promotion Training
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 5, 2026, 4:55 AM EDT
Not listed No phase listed Observational

The Effects of Explosive Blast as Compared to Post-Traumatic Stress Disorder on Brain Function and Structure

NCT00631436
View directory record Official record
Conditions
Blast Injuries, Traumatic Brain Injury, Post-Traumatic Stress Disorders
Interventions
Not listed
Lead sponsor
Center for Veterans Research and Education
Other
Eligibility
20 Years to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2011 · Synced Oct 5, 2026, 4:55 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Somatic Psychoeducational Intervention

NCT06580119
View directory record Official record
Conditions
Work Related Stress
Interventions
Somatic Psychoeducational Intervention
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Oct 5, 2026, 4:55 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Assessing and Enhancing Social Support

NCT05187156
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Behavioral Activation and Social Engagement, Treatment as usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Oct 5, 2026, 4:55 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lifestyle and Cardiometabolic Risk in Post-9/11 Veterans

NCT04911153
View directory record Official record
Conditions
PTSD, Cardiovascular Disease, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Oct 5, 2026, 4:55 AM EDT
Recruiting Phase 2 Interventional

HBOT Effects on First Responders' Cognition and Well-Being

NCT07852728
View directory record Official record
Conditions
Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Anxiety, Depression, Post Concussion Symptoms
Interventions
Hyperbaric Oxygen Therapy (HBOT)
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 5, 2026, 4:55 AM EDT