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ClinicalTrials.gov public records Last synced Oct 10, 2026, 5:51 PM EDT

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Showing 145–168 of 1,791 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Trauma and Stressor Related Disorder Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

AI to Support Mental Health Case Management Providers

NCT06280170
View directory record Official record
Conditions
Depressive Disorder, Anxiety Disorders, Substance Use Disorders, Post Traumatic Stress Disorder
Interventions
Artificial Intelligence platform for case managers
Other
Lead sponsor
Eleos Health
Industry
Eligibility
18 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Alton, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 28, 2024 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Phase 1 Interventional

Guanfacine for the Treatment of Post Traumatic Stress Disorder (PTSD)

NCT00018603
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
guanfacine
Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 10, 2026, 5:51 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Mindful Yoga Therapy as an Adjunctive Treatment for PTSD Among OEF/OIF Veterans

NCT01521442
View directory record Official record
Conditions
PTSD
Interventions
Mindful Yoga Therapy, Wait-list Control
Behavioral
Lead sponsor
VA Connecticut Healthcare System
Federal
Eligibility
18 Years to 45 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

Telephone Intervention to Increase Safety in Abused Women

NCT00457522
View directory record Official record
Conditions
Intimate Partner Violence
Interventions
Nurse/community health worker telephone intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 18, 2018 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional

ERP to Improve Functioning in Veterans With OCD

NCT05240924
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
Interventions
Exposure and Response Prevention, Stress Management Training
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
18
States / cities
East Orange, New Jersey • Buffalo, New York • New York, New York + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Terminated Not applicable Interventional Results available

Exercise Maintenance in Chronic Pain and PTSD

NCT03644927
View directory record Official record
Conditions
Chronic Low Back Pain, Posttraumatic Stress Disorder
Interventions
Progressive exercise training, Waitlist Control
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Jamaica Plain, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional

Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans

NCT06162741
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD), Depression, Anxiety
Interventions
Primary Care Brief Mindfulness Training (PCBMT), Moving Forward (MF)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Phoenix, Arizona • San Diego, California • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Motivational Interviewing to Engage Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans in Mental Health Treatment

NCT00419029
View directory record Official record
Conditions
Combat Disorders, Stress Disorders, Post-Traumatic, Depression, Substance-Related Disorders
Interventions
telephone-administered motivational interviewing, control
Behavioral
Lead sponsor
San Francisco Veterans Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2014 · Synced Oct 10, 2026, 5:51 PM EDT
Terminated Phase 2 Interventional

Exercise: A Novel Treatment for Combat Post Traumatic Stress Disorder

NCT01626131
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
exercise training, Stretching training
Behavioral
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2013 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Results available

HIRREM Developmental Study

NCT02709369
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Anxiety, Post-Traumatic Stress Disorder, Hot Flashes, Headache, Traumatic Brain Injury, Post Concussion Symptoms
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
11 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 24, 2019 · Synced Oct 10, 2026, 5:51 PM EDT
Enrolling by invitation Phase 2 Interventional

MDMA Plus Exposure Therapy for PTSD

NCT05746572
View directory record Official record
Conditions
PTSD
Interventions
MDMA
Drug
Lead sponsor
Emory University
Other
Eligibility
21 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Not listed Phase 2 Interventional

Carvedilol Versus Placebo for Treatment in Post Traumatic Stress Disorder (PTSD)

NCT01221792
View directory record Official record
Conditions
Post-Traumatic Stress Disorder
Interventions
Carvedilol, Placebo
Drug
Lead sponsor
Columbia Northwest Pharmaceuticals
Industry
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
San Diego, California • Lake Charles, Louisiana • Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Jun 8, 2011 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

Peer-led Trauma Therapy for Re-entry

NCT06019767
View directory record Official record
Conditions
PTSD
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Neuromodulation of Trauma Memories in PTSD & Alcohol Dependence

NCT01055171
View directory record Official record
Conditions
Alcohol Dependence, PTSD
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 100 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 8, 2016 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Results available

rTMS for PTSD Comorbid With Major Depressive Disorder

NCT02273063
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Major Depressive Disorder, Transcranial Magnetic Stimulation, Repetitive
Interventions
Transcranial Magnetic Stimulation (TMS)
Device
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 4, 2018 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Remote Exercise for Learning Anger and Excitation Management

NCT02132793
View directory record Official record
Conditions
Anger, Stress Disorders, Post-Traumatic
Interventions
Anger Management Therapy, Anger Management Therapy & RELAX app
Behavioral
Lead sponsor
VA Pacific Islands Health Care System
Federal
Eligibility
18 Years and older · Male only
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional

Short-Term Exposure for PTSD

NCT02874898
View directory record Official record
Conditions
Chronic Post-Traumatic Stress Disorder, Marijuana Abuse
Interventions
Brief Imaginal Exposure
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional

A Frequency-Modulated Music Intervention to Enhance Cognitive Processing Therapy (CPT) for PTSD

NCT06925867
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder
Interventions
Frequency Filtered Music, Unfiltered Music, Cognitive Processing Therapy for PTSD
Other · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Columbus, Ohio • Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Results available

Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance

NCT00108628
View directory record Official record
Conditions
Post-traumatic Stress Disorder
Interventions
Imagery Rehearsal, Sleep and Nightmare Management
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
Not listed
Enrollment
134 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2015 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Digital Resilience Intervention for Emergency Medical Service Workers

NCT06861400
View directory record Official record
Conditions
Feasibility, Acceptability, Adoptability, Meaning Made, Adaptive Self-reflection, Recovery Activities, Recovery Experiences, Post Traumatic Stress Disorder PTSD, Anxiety, Depression
Interventions
Self-Reflective Resilience-Recovery Activity Promotion Training
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 10, 2026, 5:51 PM EDT
Not yet recruiting Not applicable Interventional

A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression Symptoms

NCT06689787
View directory record Official record
Conditions
Psychosocial Functioning, Stress Disorders, Post-Traumatic, Depressive Disorder, Major
Interventions
Self-Guided STAIR Coach with Real-Time Assessment, Real-Time Assessment
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional

Neurostimulation Versus Therapy for Problems With Emotions

NCT05712057
View directory record Official record
Conditions
Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders, OCD, Impulse Control Disorder, Eating Disorders, Emotional Dysfunction, Emotional Instability, Emotional Distress, Emotional Maladjustment, Emotional Impulsivity, Obsessive-Compulsive Disorder, Emotion Dysregulation, Borderline Personality Disorder
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring, Emotional Awareness Training
Device · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 10, 2026, 5:51 PM EDT
Completed Not applicable Interventional Results available

Assessing Inflammatory and Behavioral Pathways Linking PTSD to Increased Asthma Morbidity in WTC Workers

NCT04552301
View directory record Official record
Conditions
Asthma, PTSD
Interventions
Cognitive Processing Therapy, Psychotherapy, Targeted Asthma Education, General Asthma Education
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
361 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 10, 2026, 5:51 PM EDT
Recruiting Not applicable Interventional

Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy

NCT03755401
View directory record Official record
Conditions
PTSD
Interventions
TFPP, TAU
Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 10, 2026, 5:51 PM EDT