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Showing 1–24 of 1,673 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Traumas, Brain Clear all
Completed Not applicable Interventional

Life Improvement Following Traumatic Brain Injury

NCT00878150
View directory record Official record
Conditions
Traumatic Brain Injury, Depression
Interventions
In-person Cognitive Behavioral Therapy, Telephone Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 17, 2013 · Synced Sep 2, 2026, 8:20 AM EDT
Recruiting No phase listed Observational

Cranial Ultrasound for Point of Care Intracranial Pathology Detection in Pediatrics

NCT06697808
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
Up to 18 Years
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 23, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Relationship Between Attention and Emotional Regulation Post-Traumatic Brain Injury (TBI)

NCT01681589
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Transcranial Direct Current Stimulator (TDCS), Control Group, Healthy Control Group
Device · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Sep 2, 2026, 8:20 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Validation of Cognitive Enhancement Techniques for Mild Traumatic Brain Injury

NCT04245124
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Strategic Memory Advanced Reasoning Training, Traditional Cognitive Rehabilitation
Other
Lead sponsor
The Defense and Veterans Brain Injury Center
Federal
Eligibility
Not listed
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Oceanside, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Sep 2, 2026, 8:20 AM EDT
Terminated No phase listed Observational

Hypertonic Modulation of Inflammation Following Injury

NCT00750997
View directory record Official record
Conditions
Hemorrhagic Shock, Traumatic Brain Injury
Interventions
hypertonic saline
Drug
Lead sponsor
University of Washington
Other
Eligibility
15 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 30, 2017 · Synced Sep 2, 2026, 8:20 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cervical Spinal Cord Associative Plasticity

NCT07539025
View directory record Official record
Conditions
Cervical Spinal Cord Plasticity
Interventions
SCAP, MagPro X100, Digitimer DS8R, Paired non-associative stimulation
Other · Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Not yet recruiting Not applicable Interventional

A Pilot Study of Home-Based Rhythmic Auditory Stimulation to Evaluate Mobility, Balance, and Patient-Reported Outcomes After Traumatic Brain Injury

NCT07702513
View directory record Official record
Conditions
Traumatic Brain Injury, Traumatic Brain Injury | Patient, TBI, TBI-Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Interventions
Home-Based Rhythmic Auditory Stimulation
Device
Lead sponsor
Craig Hospital
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Completed No phase listed Observational

Non-blinded Data Collection Study of Concussion Using the BrainPulse(TM)

NCT02812225
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury
Interventions
BrainPulse
Device
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
5 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
3
States / cities
Boston, Massachusetts • Cincinnati, Ohio • Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 2, 2026, 8:20 AM EDT
Recruiting Phase 2 Interventional

Improving Neurotrauma by Depolarization Inhibition With Combination Therapy (INDICT)

NCT05337618
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Full-band Electrocorticography, Treatment Algorithm
Diagnostic Test · Combination Product
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 80 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 2, 2026, 8:20 AM EDT
Recruiting No phase listed Observational

Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury

NCT06480838
View directory record Official record
Conditions
Traumatic Brain Injury With Loss of Consciousness, Brain Injury Traumatic Severe, Brain Injury Traumatic Moderate, TBI (Traumatic Brain Injury), TBI
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
3
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Terminated Not applicable Interventional Results available

Proprioception Testing in Persons With Sensorimotor Impairment

NCT01974635
View directory record Official record
Conditions
Spinal Cord Injury, Stroke, Acquired Brain Injury
Interventions
AMES Therapy
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 12, 2019 · Synced Sep 2, 2026, 8:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Estimating Brain Biomechanics Using MRI

NCT01633268
View directory record Official record
Conditions
Healthy Volunteer, Traumatic Brain Injury, Brain Mapping, Craniocerebral Trauma, Magnetic Resonance Imaging
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 2, 2026, 8:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Proteomics of Brain Trauma-associated Elevated Intracranial Pressure (ICP)

NCT00178659
View directory record Official record
Conditions
Brain Injuries, Traumatic, Traumatic Brain Injury
Interventions
Blood/saliva samples for protein/molecular analysis
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
14 Years to 65 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Recruiting No phase listed Observational

Assessment of the Efficacy of Medrol Dose Pack for Acute Post-Concussive Headaches

NCT04685772
View directory record Official record
Conditions
Post-Concussion Syndrome, Headache
Interventions
Methylprednisolone
Drug
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
25 participants
Timeline
2021 – 2027
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Completed No phase listed Observational

Acute Cognitive and Neurobehavioral Intervention: Efficacy Evaluation

NCT00205569
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
First Steps Educational Curriculum
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Sep 2, 2026, 8:20 AM EDT
Recruiting No phase listed Observational

Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Single Center

NCT07324551
View directory record Official record
Conditions
Chronic Subdural Hematoma, Hemorrhage Brain
Interventions
Matched pair Aristotle 14 guidewire and Plato 17 microcatheter, Surgeon combination preference
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Completed Not applicable Interventional

Case Studies: Promoting Strategy Use in Functional Activities

NCT04363645
View directory record Official record
Conditions
Cognitive Impairment, Executive Dysfunction, Acquired Brain Injury
Interventions
Multicontext (MC) approach
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 80 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2020 · Synced Sep 2, 2026, 8:20 AM EDT
Completed Phase 2 Interventional Results available

Prospective Analysis of the Use of N-Acetylcysteine and Vitamins in the Treatment of TBI in Geriatric Patients

NCT04291066
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
N-Acetyl cysteine
Drug
Lead sponsor
HonorHealth Research Institute
Other
Eligibility
60 Years to 100 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Completed Not applicable Interventional

Brain and Nerve Stimulation for Hand Muscles in Spinal Cord Injury and ALS

NCT02469675
View directory record Official record
Conditions
Spinal Cord Injury (SCI), Amyotrophic Lateral Sclerosis (ALS)
Interventions
Transcranial magnetic stimulation, Median nerve stimulation, Cervical transcutaneous stimulation
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
21 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2018 · Synced Sep 2, 2026, 8:20 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Exploratory Study to Evaluate 2 Acupuncture Methods for the Treatment of Headaches Associated With TBI

NCT01338701
View directory record Official record
Conditions
Headache, Traumatic Brain Injury
Interventions
Traditional Chinese Acupuncture (TCA), Auricular (Ear) Acupuncture, Usual Care
Procedure · Other
Lead sponsor
Samueli Institute for Information Biology
Other
Eligibility
18 Years to 69 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated May 12, 2016 · Synced Sep 2, 2026, 8:20 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

NCT06195345
View directory record Official record
Conditions
HIE, TBI (Traumatic Brain Injury), TBI, Hemodynamic Instability, Hypoxic-Ischemic Encephalopathy
Interventions
MR Imaging
Diagnostic Test
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
1 Minute to 18 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2035
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study to Test the SENSE Device in Military-Age Patients With Traumatic Brain Injury

NCT05155800
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
SDx3
Device
Lead sponsor
Sense Diagnostics, LLC
Industry
Eligibility
22 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
Atlanta, Georgia • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Sep 2, 2026, 8:20 AM EDT
Not yet recruiting Not applicable Interventional

Postural Motor Activation Deficits After mTBI; Translating Laboratory Findings to Clinical Care

NCT07549529
View directory record Official record
Conditions
Mild Traumatic Brain Injury (mTBI), Concussion, Mild Traumatic Brain Injury
Interventions
Motor Activation Physical Therapy for mTBI, Standard of Care Physical Therapy for mTBI
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Portland, Oregon • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 2, 2026, 8:20 AM EDT
Completed Not applicable Interventional

Evaluation of the Veterans' In-home Program

NCT01831830
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
The Veterans' In-home Program
Behavioral
Lead sponsor
Corporal Michael J. Crescenz VA Medical Center
Federal
Eligibility
18 Years and older
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2015 · Synced Sep 2, 2026, 8:20 AM EDT