- Conditions
- Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
- Interventions
- Total Knee Arthroplasty
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 760 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2035
- U.S. locations
- 16
- States / cities
- Parker, Colorado • Tampa, Florida • Atlanta, Georgia + 13 more
Search Results
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Other Inflammatory Arthritis, Post-Traumatic Arthritis, Juvenile Rheumatoid Arthritis, Avascular Necrosis
- Interventions
- Total Knee Arthroplasty, Total knee replacement
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 149 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2001 – 2007
- U.S. locations
- 3
- States / cities
- Greensboro, North Carolina • Austin, Texas • Lakewood, Washington
- Conditions
- Osteoarthritis of the Knee, Traumatic Arthritis of the Knee
- Interventions
- Total knee arthroplasty
- Procedure
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 20 Years to 75 Years
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2021
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Rhematoid Arthritis, Osteo Arthritis of the Knee, Traumatic Arthritis of Knee (Diagnosis), Polyarthritis, Collagen Disorders, Avascular Necrosis of Femoral Condyle, Valgus Deformity, Varus Deformity, Flexion Deformity of Knee
- Interventions
- Total knee arthroplasty
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2037
- U.S. locations
- 2
- States / cities
- Denver, Colorado • Baltimore, Maryland
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Juvenile Arthritis
- Interventions
- Total knee arthroplasty
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 210 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 3
- States / cities
- Denver, Colorado • Pittsburgh, Pennsylvania • Virginia Beach, Virginia
- Conditions
- Osteoarthritis, Traumatic Arthritis, Rheumatoid Arthritis, Lower Limb Deformity, Complications, Arthroplasty
- Interventions
- Vanguard™ Complete Knee System, Vanguard™ Patient-Specific Femur
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 552 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2024
- U.S. locations
- 8
- States / cities
- Cedar Rapids, Iowa • Rockville, Maryland • Cape Girardeau, Missouri + 5 more
- Conditions
- Osteoarthritis, Avascular Necrosis, Traumatic Arthritis, Conditional Tibial Condyle or Plateau Fractures, Conditional Revision of the Articular Surface
- Interventions
- Persona Partial Knee system
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 757 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2030
- U.S. locations
- 9
- States / cities
- Fremont, California • Golden, Colorado • Chicago, Illinois + 6 more
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
- Interventions
- Maxim® Knee System with Removable Molded Polyethylene Tibia, Regular Maxim® Knee System
- Device
- Lead sponsor
- Biomet Orthopedics, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2007
- U.S. locations
- 1
- States / cities
- Warsaw, Indiana
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of the Knee, Avascular Necrosis, Patellofemoral Osteoarthritis
- Interventions
- Zimmer Biomet Persona Ti-Nidium Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2034
- U.S. locations
- 7
- States / cities
- Parker, Colorado • Hyattsville, Maryland • Jackson, Mississippi + 4 more
- Conditions
- Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, Quadriceps Muscle Atrophy
- Interventions
- Experimental: Whole Body Vibration, Experimental: Local Muscle Vibration, Standard ACL Rehabilitation
- Device · Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 16 Years to 35 Years
- Enrollment
- 114 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 2
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Post-traumatic Osteoarthritis of the Knee
- Interventions
- FX006 32 mg, TCA IR 40 mg
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 20 Years to 50 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Arthropathy of Knee
- Interventions
- Scorpio® CR Total Knee System
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 215 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2001
- U.S. locations
- 5
- States / cities
- Little Rock, Arkansas • Indianapolis, Indiana • Louisville, Kentucky + 2 more
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
- Interventions
- 3DKnee™ System
- Device
- Lead sponsor
- Encore Medical, L.P.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 229 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2018
- U.S. locations
- 8
- States / cities
- Scottsdale, Arizona • Fresno, California • Baltimore, Maryland + 5 more
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Lower Limb Deformity, Post-traumatic Deformity, Complications, Arthroplasty
- Interventions
- Vanguard XP Bicruciate Knee System, Vanguard CR Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Salt Lake City, Utah
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Triathlon PKR
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 21 Years to 75 Years
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2023
- U.S. locations
- 6
- States / cities
- Jacksonville, Florida • Egg Harbor, New Jersey • Buffalo, New York + 3 more
- Conditions
- Rheumatoid Arthritis, Traumatic Arthritis, Joint Disease Secondary to Osteoarthritis
- Interventions
- Encore 3DKnee™ system, Encore MJS™ Knee System
- Device
- Lead sponsor
- Encore Medical, L.P.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Fresno, California
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity, Complications; Arthroplasty, Deformity of Limb
- Interventions
- Vanguard SSK 360 with PS Bearing, Vanguard SSK 360 with PSC bearing, Vanguard DA 360, Vanguard 360 TiNbN Femur with PS bearing, Vanguard 360 TiNbN Femur with PSC bearing
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 255 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2031
- U.S. locations
- 4
- States / cities
- Morton Grove, Illinois • Henderson, Nevada • Salt Lake City, Utah + 1 more
- Conditions
- Degenerative Joint Disease of Knee, Osteoarthritis, Traumatic Arthritis, Varus Deformity, Knee Pain Chronic
- Interventions
- Persona Partial Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- Not listed
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2030
- U.S. locations
- 1
- States / cities
- Jackson, Mississippi
- Conditions
- Osteoarthritis of the Knee
- Interventions
- ATTUNE Cementless CR Fixed Bearing, ATTUNE Cementless PS Fixed Bearing
- Device
- Lead sponsor
- DePuy Orthopaedics
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 80 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 15
- States / cities
- Irvine, California • Bradenton, Florida • DeLand, Florida + 10 more
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Inflammatory Tissue Disorders, Arthritis Secondary to Other Diseases, Avascular Necrosis of the Femoral Condyles
- Interventions
- Foundation Knee
- Device
- Lead sponsor
- Encore Medical, L.P.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Vero Beach, Florida
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Knee Arthritis
- Interventions
- Simplex® Bone Cement, Cobalt™ Bone Cement
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Warsaw, Indiana
- Conditions
- Osteoarthritis, Post Traumatic Degenerative Disease
- Interventions
- EPIK™ uni-compartmental knee
- Device
- Lead sponsor
- Encore Medical, L.P.
- Industry
- Eligibility
- 18 Years to 60 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Kyle, Texas
- Conditions
- Inflammatory Arthritis, Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis), Post-traumatic Arthritis
- Interventions
- Cemented CoCr, Cemented Oxinium, Cementless
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 144 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2036
- U.S. locations
- 6
- States / cities
- Phoenix, Arizona • Orlando, Florida • Newton, Massachusetts + 3 more
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Moderate Varus, Valgus or Flexion Deformities, Avascular Necrosis of the Femoral Condyle
- Interventions
- Zimmer Persona Total Knee System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 737 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2027
- U.S. locations
- 14
- States / cities
- Denver, Colorado • Fort Collins, Colorado • Parker, Colorado + 11 more