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ClinicalTrials.gov public records Last synced Sep 13, 2026, 10:48 PM EDT

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Showing 1–24 of 342 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Traumatic Brain Injury, Mild Clear all
Active, not recruiting No phase listed Observational

Utilizing Electronic Clinical Decision Support to Enhance mTBI Care at the Primary Care Point of Entry

NCT06693778
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury
Interventions
electronic Clinical Decision Support tool for risk stratification of pediatric patients with mTBI
Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 18 Years
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Sep 13, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Remotely Supervised tDCS for Persistent Post-traumatic Headache

NCT04012853
View directory record Official record
Conditions
Persistent Post Traumatic Headache, Mild Traumatic Brain Injury
Interventions
transcranial direct current stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 13, 2026, 10:48 PM EDT
Completed Early Phase 1 Interventional

Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury

NCT04280965
View directory record Official record
Conditions
Post Traumatic Stress Disorder
Interventions
Quetiapine Fumarate, Standard of care meducations
Drug · Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Sep 13, 2026, 10:48 PM EDT
Not listed Not applicable Interventional

PoNS Clinical Experience Program (TBI)

NCT03852732
View directory record Official record
Conditions
Mild to Moderate Traumatic Brain Injury
Interventions
PoNS Treatment
Device
Lead sponsor
Helius Medical Inc
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Sep 13, 2026, 10:48 PM EDT
Completed No phase listed Observational

Objective Brain Function Assessment of mTBI/Concussion in High School Athletes

NCT02661633
View directory record Official record
Conditions
Brain Injuries, Traumatic, Concussion, Brain, Concussion, Mild, Concussion, Intermediate, Concussion, Severe
Interventions
BrainScope Ahead 200iD, Advanced MRI Neuroimaging
Device
Lead sponsor
BrainScope Company, Inc.
Industry
Eligibility
13 Years to 19 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
4
States / cities
Fayetteville, Arkansas • Bethesda, Maryland • East Lansing, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Sep 13, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Combining Attention and Metacognitive Training to Improve Goal Directed Behavior in Veterans With TBI

NCT04044456
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Goal Management Training, Attention Training, Brain Health Workshop, National geographic movies
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Sep 13, 2026, 10:48 PM EDT
Active, not recruiting No phase listed Observational

Head and Intraocular Trauma Tool for the Identification of Mild Traumatic Brain Injury

NCT05092295
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
Head and Intraocular Trauma Tool, SCAT-5
Device · Diagnostic Test
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
13 Years to 45 Years
Enrollment
200 participants
Timeline
2021 – 2027
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 13, 2026, 10:48 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Neuroimaging & Plasma Markers for Predicting Outcomes After Mild Traumatic Brain Injury

NCT02891941
View directory record Official record
Conditions
Traumatic Brain Injury, Injury of Body Region
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 7, 2016 · Synced Sep 13, 2026, 10:48 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

The TCU Division I Collegiate Athlete Study

NCT07006051
View directory record Official record
Conditions
Orthopaedic Injuries, Concussion (Diagnosis)
Interventions
Exposed group
Other
Lead sponsor
Texas Christian University
Other
Eligibility
17 Years to 30 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 13, 2026, 10:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of Brain Aging in Vietnam War Veterans

NCT01687153
View directory record Official record
Conditions
Traumatic Brain Injury, Post Traumatic Stress Disorder, Alzheimer's Disease, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of Southern California
Other
Eligibility
50 Years to 90 Years
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2021
U.S. locations
19
States / cities
Sun City, Arizona • Irvine, California • La Jolla, California + 14 more
Source: ClinicalTrials.gov public record
Updated Nov 28, 2021 · Synced Sep 13, 2026, 10:48 PM EDT
Active, not recruiting Not applicable Interventional

Mobile Subthreshold Exercise Program for Concussion--R01

NCT04688255
View directory record Official record
Conditions
Concussion, Brain, Concussion, Mild, Brain Injuries, Traumatic, Persistent Post Traumatic Headache, Post-Concussion Syndrome, Post-Concussive Syndrome, Chronic
Interventions
MSTEP, Stretching
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Sep 13, 2026, 10:48 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)

NCT00714571
View directory record Official record
Conditions
Mild Cognitive Impairment, Alzheimer's Disease, Traumatic Brain Injury
Interventions
Mnemonic strategy training (MST), Repeated exposure (XP), Subtracting Cues training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 88 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 3, 2017 · Synced Sep 13, 2026, 10:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Prospective Study of Brain Network Activation (BNA) Changes in High School Athletes Following Concussion

NCT01673464
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
ElMindA Ltd
Industry
Eligibility
13 Years to 18 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Sep 13, 2026, 10:48 PM EDT
Recruiting Phase 3 Interventional

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

NCT04867317
View directory record Official record
Conditions
Adult Growth Hormone Deficiency, Mild Traumatic Brain Injury
Interventions
Somatropin, Placebo
Drug · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 55 Years
Enrollment
172 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
16
States / cities
Birmingham, Alabama • Phoenix, Arizona • San Diego, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 13, 2026, 10:48 PM EDT
Not listed Not applicable Interventional

Transcranial Magnetic Stimulation (TMS) to Treat mTBI and PTSD

NCT02458521
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Traumatic Stress Disorder
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Device
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 19, 2015 · Synced Sep 13, 2026, 10:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Mild TBI in Collegiate Athletes

NCT02189525
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Banyan Biomarkers, Inc
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Sep 13, 2026, 10:48 PM EDT
Completed No phase listed Observational

Defining Axonal Injury in Children With Mild Traumatic Brain Injury

NCT01922531
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 16 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 13, 2013 · Synced Sep 13, 2026, 10:48 PM EDT
Completed No phase listed Observational

Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment

NCT03265912
View directory record Official record
Conditions
Concussion, Mild, TBI (Traumatic Brain Injury), Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
ElMindA Ltd
Industry
Eligibility
15 Years to 50 Years
Enrollment
46 participants
Timeline
2017 – 2018
U.S. locations
2
States / cities
New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Sep 13, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions

NCT01814527
View directory record Official record
Conditions
Mild Concussion, Brain Concussion, Cerebral Concussion
Interventions
Docosahexaenoic acid, Placebo
Dietary Supplement · Drug
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 40 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Sep 13, 2026, 10:48 PM EDT
Recruiting Not applicable Interventional

Use of Tinted Contact Lenses for Concussion-Related Light Sensitivity

NCT07223086
View directory record Official record
Conditions
Concussion, Mild, Photophobia, Contact Lens
Interventions
Narrow band (tinted) contact lenses, broad band (clear) contact lenses
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 13, 2026, 10:48 PM EDT
Recruiting Not applicable Interventional

Goal-oriented Telehealth Rehabilitation of Executive Functioning for Veterans With Chronic TBI

NCT07190365
View directory record Official record
Conditions
Mild to Moderate Traumatic Brain Injury, Cognitive Rehabilitation, Veteran
Interventions
GOALS TH, EDU TH
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Sep 13, 2026, 10:48 PM EDT
Recruiting Phase 1 Interventional

Regulation of Emotion, Sleep Extension, and mTBI

NCT06883006
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Sleep Extension
Behavioral
Lead sponsor
Merrimack College
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
North Andover, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Sep 13, 2026, 10:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Understanding Concussion/Mild Traumatic Brain Injury

NCT03381638
View directory record Official record
Conditions
Traumatic Brain Injury, Concussion, Brain
Interventions
Blink Reflexometer
Device
Lead sponsor
Blinktbi, Inc.
Industry
Eligibility
14 Years and older
Enrollment
477 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
5
States / cities
Charlotte, North Carolina • Hershey, Pennsylvania • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Sep 13, 2026, 10:48 PM EDT
Completed Not applicable Interventional Results available

Traditional Balance vs Vibrotactile Feedback Training for Vestibular Rehabilitation

NCT01672658
View directory record Official record
Conditions
Traumatic Brain Injury, Vestibular Deficits
Interventions
Sensory Kinetics Balance System, Traditional Vestibular Rehabilitation
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 3, 2016 · Synced Sep 13, 2026, 10:48 PM EDT