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ClinicalTrials.gov public records Last synced Sep 15, 2026, 10:01 PM EDT

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Showing 1–24 of 342 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Traumatic Brain Injury, Mild Clear all
Withdrawn Not applicable Interventional

Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain Injury

NCT06380985
View directory record Official record
Conditions
Alcohol Use Disorder, Mild-Moderate Traumatic Brain Injury
Interventions
Personalized VR Alcohol Approach Bias Modification (ApBM) Condition, Sham Condition
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Not applicable Interventional

TBI Evaluation and Management (TEaM)

NCT04576715
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
TEaM Intervention, Standard of Care
Behavioral
Lead sponsor
Emory University
Other
Eligibility
5 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Sep 15, 2026, 10:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Head Trauma on Collegiate Athletes

NCT02354469
View directory record Official record
Conditions
Cerebral Concussion, Brain Injuries
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 25 Years
Enrollment
437 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 17, 2023 · Synced Sep 15, 2026, 10:01 PM EDT
Recruiting Not applicable Interventional

rTMS for Military TBI-related Depression

NCT05426967
View directory record Official record
Conditions
Depressive Symptoms, Mild Traumatic Brain Injury, Concussion
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS), Sham rTMS
Device
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Palo Alto, California • Fort Bliss, Texas • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 15, 2026, 10:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Passive Neurosensory Reintegration Training as a Tool to Augment Mild Traumatic Brain Injury

NCT07356167
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Passive neurosensory reintegration training (PNRT)
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Not applicable Interventional Results available

Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury

NCT04504630
View directory record Official record
Conditions
Amnestic Mild Cognitive Impairment, Traumatic Brain Injury, Mild Traumatic Brain Injury
Interventions
High Definition Transcranial Direct Current Stimulation, Sham HD-tDCS
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Not applicable Interventional

Acupressure and Stress Resilience

NCT01614444
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Mild Traumatic Brain Injury (mTBI)
Interventions
Active Acupressure Treatment, Placebo Acupressure Treatment
Other
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rural Veterans With Post-traumatic Stress Disorder (PTSD) And Comorbid Mild Traumatic Brain Injury (TBI): A Feasibility Study

NCT01278316
View directory record Official record
Conditions
Post-Traumatic Stress Disorders, Traumatic Brain Injury
Interventions
Control, Cognitive Training
Behavioral
Lead sponsor
Michael E. DeBakey VA Medical Center
Federal
Eligibility
20 Years to 40 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 21, 2018 · Synced Sep 15, 2026, 10:01 PM EDT
Enrolling by invitation Not applicable Interventional

Pilot TMS in Mild TBI

NCT06999304
View directory record Official record
Conditions
Persistent Post Concussive Headache, Mild Traumatic Brain Injury
Interventions
Intermittent theta burst stimulation
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Phase 1 Interventional

Vagus Nerve Stimulation to Treat Moderate Traumatic Brain Injury

NCT02974959
View directory record Official record
Conditions
Traumatic Brain Injury, Acute Brain Injuries
Interventions
gammaCore active device, gammaCore sham device
Device
Lead sponsor
CentraCare
Other
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 3, 2021 · Synced Sep 15, 2026, 10:01 PM EDT
Completed No phase listed Observational

Oculogica Portable EyeBOX Study

NCT05047003
View directory record Official record
Conditions
Concussion, Brain, Mild Traumatic Brain Injury
Interventions
EyeBOX Model EBX-4 (Portable version)
Diagnostic Test
Lead sponsor
Oculogica, Inc.
Industry
Eligibility
5 Years to 67 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
4
States / cities
Redlands, California • Saint Cloud, Minnesota • Green Bay, Wisconsin + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Not applicable Interventional

Internet-guided Cognitive Behavioral Therapy for Insomnia in Military Service Members With History of TBI

NCT04377009
View directory record Official record
Conditions
Insomnia Chronic, Mild Traumatic Brain Injury
Interventions
Sleep Healthy Using the Internet (SHUTi), Education Control Program
Device · Other
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 64 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 15, 2026, 10:01 PM EDT
Terminated Phase 3 Interventional Results available

Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury

NCT00983437
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Armodafinil
Drug
Lead sponsor
Cephalon, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
61
States / cities
Birmingham, Alabama • Tucson, Arizona • Hot Springs, Arkansas + 49 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Sep 15, 2026, 10:01 PM EDT
Not listed No phase listed Observational

Follow-up of MTBI Patients Discharged from the ED Using Standard Clinical Triage Including BrainScope One

NCT04279431
View directory record Official record
Conditions
TBI (Traumatic Brain Injury), Concussion, Brain, MTBI - Mild Traumatic Brain Injury, Closed Head Injury
Interventions
EEG Recording, Neurocognitive Tests, Clinician Evaluation, 22-item CSI
Device · Other
Lead sponsor
BrainScope Company, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
660 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
7
States / cities
Detroit, Michigan • Royal Oak, Michigan • Troy, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2024 · Synced Sep 15, 2026, 10:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Psychological and Vestibular Health: MINDGAPS

NCT05986279
View directory record Official record
Conditions
Vestibular Hypofunction
Interventions
Rehab
Other
Lead sponsor
University of Montana
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
2
States / cities
San Diego, California • Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Return to Learn Implementation Bundle for Schools (RISE) After Youth Concussion

NCT04635475
View directory record Official record
Conditions
Concussion, Mild
Interventions
RISE Bundle
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
14 Years to 19 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Sep 15, 2026, 10:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Advanced MRI Applications for Mild Traumatic Brain Injury

NCT02070588
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Traumatic Brain Injury
Interventions
MRI
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
15 Years to 50 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Sep 15, 2026, 10:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

NCT07044596
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Post Concussion Syndrome
Interventions
Functional near-infrared spectroscopy (fNIRS), V1 stimulation electrodes, Magnetic Resonance Imaging (MRI), MAGNUS scanner
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
20 Years to 85 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 15, 2026, 10:01 PM EDT
Active, not recruiting Phase 2 Interventional

Pilot rTMS for AUD+mTBI

NCT03995173
View directory record Official record
Conditions
Alcohol Use Disorder, Mild Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
repetitive transcranial magnetic stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 25, 2025 · Synced Sep 15, 2026, 10:01 PM EDT
Terminated Not applicable Interventional

Cooling Helmets to Decrease Concussion Symptoms

NCT05473897
View directory record Official record
Conditions
Concussion, Mild, TBI (Traumatic Brain Injury)
Interventions
Catalyst Cryohelmet
Device
Lead sponsor
Corewell Health South
Other
Eligibility
19 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Saint Joseph, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 15, 2026, 10:01 PM EDT
Completed No phase listed Observational

Service Member Fatigue and Lack of Motivation Following Concussion

NCT01496586
View directory record Official record
Conditions
Fatigue, Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Not applicable Interventional

Pro-2-Cool Device Clinical Study

NCT03511339
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
TecTraum device
Device
Lead sponsor
TecTraum Inc.
Industry
Eligibility
12 Years to 21 Years
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
5
States / cities
Ann Arbor, Michigan • Akron, Ohio • Boardman, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Sep 15, 2026, 10:01 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

An fMRI Study of Attention and Effort After Concussion

NCT00653029
View directory record Official record
Conditions
Post Concussive Syndrome
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2016 · Synced Sep 15, 2026, 10:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Transcranial Electrical Stimulation for mTBI

NCT03244475
View directory record Official record
Conditions
Mild Traumatic Brain Injury (mTBI), Post-traumatic Stress Disorder
Interventions
TES
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Sep 15, 2026, 10:01 PM EDT