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ClinicalTrials.gov public records Last synced Sep 17, 2026, 9:58 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Traumatic Wounds Clear all
Completed Phase 1Phase 2 Interventional

Effects of Rapid-Resisted Exercise and Bright Light Therapy on Ambulatory Adults With Traumatic Brain Injury

NCT01175993
View directory record Official record
Conditions
Adult, Traumatic Brain Injury, fMRI
Interventions
Elliptical exercise
Other
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 44 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Sep 17, 2026, 9:58 AM EDT
Withdrawn No phase listed Observational

Characterization of Fatigue in Military Personnel With Traumatic Brain Injuries

NCT03998358
View directory record Official record
Conditions
Traumatic Brain Injury, Neurobehavioral Manifestation, Sleep Disorder, Fatigue
Interventions
Not listed
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
25 Years to 40 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 24, 2021 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sub-acute Exercise Following Sport-Related Concussion

NCT03575455
View directory record Official record
Conditions
Sport-related Concussion
Interventions
Exercise
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
13 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 17, 2026, 9:58 AM EDT
Not listed No phase listed Observational

Appropriateness of Methodist Health System(MHS) Inter-facility Transfers of Traumatic Intracranial Subarachnoid Hemorrhage and Spontaneous Bleeds for Level-1 Advanced Surgical Intervention

NCT06136078
View directory record Official record
Conditions
Traumatic Intracranial Subarachnoid Hemorrhage
Interventions
rate of appropriate and inappropriate transfers from Methodist interfacility transfers
Other
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Phase 2 Interventional Results available

Sumatriptan as Treatment for Post-traumatic Headache

NCT01854385
View directory record Official record
Conditions
Post-traumatic Headache
Interventions
Sumatriptan 100 mg
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Sep 17, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional

Remote Stimulation and Training to Advance Recovery From TBI in Seniors

NCT07332299
View directory record Official record
Conditions
Traumatic Brain Injury, Aging Related Cognitive Decline
Interventions
Active tDCS and Cognitive Training Intervention, Sham tDCS and Cognitive Training Intervention
Combination Product
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
65 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Soccer Head Gear to Reduce Concussions

NCT02850926
View directory record Official record
Conditions
Brain Concussion
Interventions
Soccer head gear
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
14 Years to 19 Years
Enrollment
3,050 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional Results available

Online and Shared Decision-Making Interventions to Engage Service Men and Women in Post-Deployment Mental Health Care

NCT03539068
View directory record Official record
Conditions
PTSD, Depression, Substance Use Disorder, Traumatic Brain Injury
Interventions
WEB-ED+ Treatment Arm
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
1,312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Sep 17, 2026, 9:58 AM EDT
Terminated Phase 2 Interventional Results available

OPTIMA-TBI Pilot Study

NCT03345550
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Omega-3 Polyunsaturated Fatty Acids (Fish Oil 1000 mg (contains 500 mg DHA & 100 mg EPA)) or placebo capsules., Placebo - Cap
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional Results available

Musculotendinous Tissue Repair Unit and Reinforcement (MTURR)

NCT01292876
View directory record Official record
Conditions
Traumatic Injury, Muscle Injury, Tendon Injury, Soft Tissue Injury, Extremity Injury
Interventions
Extracellular Matrix
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
Bethesda, Maryland • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 6, 2020 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing and Interactive Concussion Education Platform to Current Education Standards

NCT04122274
View directory record Official record
Conditions
Concussion, Brain
Interventions
NCAA education sheet, Sham Intervention, Decision-based interactive concussive education platform
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Sep 17, 2026, 9:58 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

An Early Prospective Study of the Traq™ Device for Characterization of Binocular Ocular Function in Normal Subjects and Subjects With Recent Traumatic Brain Injury

NCT07742878
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Concussion, Binocular Visual Function, Neuro-Ophthalmology, Saccadic Eye Movements
Interventions
Binocular ophthalmic neurodiagnostic device
Device
Lead sponsor
Rebiscan, Inc.
Industry
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Waukee, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 17, 2026, 9:58 AM EDT
Terminated Phase 2 Interventional

A Safety and Efficacy Study of NNZ-2566 in Patients With Mild Traumatic Brain Injury (mTBI)

NCT02100150
View directory record Official record
Conditions
Concussion
Interventions
NNZ-2566, Placebo
Drug
Lead sponsor
Neuren Pharmaceuticals Limited
Industry
Eligibility
16 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fayetteville, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 4, 2018 · Synced Sep 17, 2026, 9:58 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Imaging [18F]PI-2620 and [18F]Florbetaben in Military Service Members With Blast Related Mild Traumatic Brain Injury

NCT05337774
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
[18F]PI-2620
Drug
Lead sponsor
Lantheus Biosciences Ltd.
Industry
Eligibility
25 Years to 54 Years · Male only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Test of Chamber Pressure to Divers and Chamber Attendants

NCT01430325
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Hyperbaric Oxygen (1.5 atm abs), Sham Chamber Session
Drug
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
2
States / cities
Murray, Utah • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 14, 2013 · Synced Sep 17, 2026, 9:58 AM EDT
Recruiting Not applicable Interventional

Evaluation of the Abbott i-STAT TBI Biomarker Test

NCT06766435
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
i-STAT TBI Test
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Sep 17, 2026, 9:58 AM EDT
Recruiting Phase 4 Interventional

Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints

NCT05776056
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD)
Interventions
Methylphenidate, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional Results available

LED Therapy for the Treatment of Concussive Brain Injury

NCT02383472
View directory record Official record
Conditions
Brain Concussion
Interventions
MedX Health Console model 1100, MedX Health Console model 1100-placebo
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
11 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 25, 2018 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional

Web-Based Self-Monitoring Activity-Restriction and Relaxation Training Program for Kids With Mild Traumatic Brain Injury

NCT03498495
View directory record Official record
Conditions
Brain Injury Traumatic Mild
Interventions
Self-Monitoring Activity-restriction and Relaxation Training (SMART)
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 18 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Sep 17, 2026, 9:58 AM EDT
Enrolling by invitation Not applicable Interventional

Brief Prolonged Exposure Therapy Versus Clinical Standard to Reduce Posttraumatic Stress Post Spinal Cord Injury

NCT05233111
View directory record Official record
Conditions
Spinal Cord Injuries, PTSD, Post-Traumatic Stress Disorder
Interventions
Brief Prolonged Exposure Therapy, Treatment as Usual
Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Use of the VOMS Tool With Military Personnel to Track mTBI Recovery and RTD Status

NCT02634944
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Vestibular Ocular Motor Screening Tool (VOMS)
Diagnostic Test
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 40 Years
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fort Lewis, Washington
Source: ClinicalTrials.gov public record
Updated Apr 5, 2020 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Phase 4 Interventional

The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury

NCT01339806
View directory record Official record
Conditions
Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With No Loss of Consciousness
Interventions
Cognitive Rehab, Brainworks, Informational Handout/Provider Visits
Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
143 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 8, 2015 · Synced Sep 17, 2026, 9:58 AM EDT
Completed No phase listed Observational

Reliability of Sensor Spacing for NIRS in Traumatic Tibia Fractures

NCT02301832
View directory record Official record
Conditions
Orthopedic Disorders, Tibial Fractures
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Sep 17, 2026, 9:58 AM EDT
Completed Not applicable Interventional

Arts and Movement Therapies for Trauma

NCT03515564
View directory record Official record
Conditions
PTSD, Depression, Anxiety, Stress, Trauma
Interventions
Dance/Movement Therapy, Art Therapy, Mindful Yoga
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
7 Years to 65 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 28, 2024 · Synced Sep 17, 2026, 9:58 AM EDT