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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:44 AM EST

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Showing 1–24 of 73 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Tricuspid Valve Disease Clear all

Conditions: Tricuspid Regurgitation (TR)
Interventions: TRiCares Topaz TTVR System, Edwards EVOQUE TTVR System; Device
Lead sponsor: TRiCares; Industry
Eligibility: 18 Years and older
Enrollment: 831 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2035
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Tricuspid Valve Insufficiency
Interventions: TRAIPTA (Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty); Device
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 21 Years to 100 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 2
States / cities: Atlanta, Georgia • Roslyn, New York

Conditions: Tricuspid Valve Disease
Interventions: CorMatrix Cor TRICUSPID ECM Valve; Device
Lead sponsor: Corvivo Cardiovascular, Inc.; Industry
Eligibility: 1 Year to 85 Years
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 4
States / cities: Mobile, Alabama • Indianapolis, Indiana • Baltimore, Maryland + 1 more

Conditions: Aortic Valve Disease
Interventions: Not listed
Lead sponsor: Baylor Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 91 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2022
U.S. locations: 1
States / cities: Plano, Texas

Conditions: Tricuspid Valve Regurgitation, Non-rheumatic, Mitral Valve Regurgitation
Interventions: Not listed
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: Not listed
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
Interventions: Application of positive-end-expiratory pressure; Other
Lead sponsor: Northwell Health; Other
Eligibility: 3 Months to 18 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Tricuspid Valve Regurgitation
Interventions: Transcatheter Tricuspid Valve Replacement; Device
Lead sponsor: inQB8 Medical Technologies, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 6
States / cities: Los Angeles, California • Thousand Oaks, California • Atlanta, Georgia + 3 more

Conditions: Tricuspid Regurgitation (TR)
Interventions: Transcatheter Tricuspid Valve Intervention; Device
Lead sponsor: Jenscare Innovation Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 3
States / cities: Los Angeles, California • Detroit, Michigan • New York, New York

Conditions: Fontan Procedure, Hypoplastic Left Heart Syndrome, Tricuspid Atresia
Interventions: Vitamin C, Placebo; Dietary Supplement
Lead sponsor: University of Michigan; Other
Eligibility: 8 Years to 25 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Tricuspid Regurgitation
Interventions: Intrepid™ TTVR System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2031
U.S. locations: 20
States / cities: Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 16 more

Conditions: Heart Valve Diseases, Heart Diseases, Cardiovascular Diseases, Tricuspid Valve Disease
Interventions: Edwards TRIFORMIS RESILIA heart valve; Device
Lead sponsor: Edwards Lifesciences; Industry
Eligibility: 18 Years and older
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2034
U.S. locations: 1
States / cities: Carmel, Indiana

Conditions: Aortic Stenosis, Disorder of Prosthetic Cardiac Valve, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Hypertrophic Cardiomyopathy, Tricuspid Valve Insufficiency
Interventions: Blood Draw; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years and older
Enrollment: 378 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2020
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Mitral Valve Regurgitation, Heart Failure, Heart Valve Disease, Tricuspid Valve Regurgitation, Aortic Valve Stenosis
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 99 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Cardiac Conduction Disorders Requiring Permanent Pacing in Patients With Prior or Planned Tricuspid Valve Intervention
Interventions: Pacemaker; Device
Lead sponsor: Minneapolis Heart Institute Foundation; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Tricuspid Regurgitation
Interventions: Edwards PASCAL Transcatheter Valve Repair System; Device
Lead sponsor: Edwards Lifesciences; Industry
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 15
States / cities: Los Angeles, California • Atlanta, Georgia • Chicago, Illinois + 11 more

Conditions: Valvular Heart Disease
Interventions: HBCR hands-off, HBCR interactive; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Tricuspid Regurgitation
Interventions: TriClipTM Device; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 572 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 63
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 51 more

Conditions: Congestive Heart Failure, Ischemic Cardiomyopathy, Mitral Valve Prolapse, Mitral Regurgitation, Aortic Valve Disease, Tricuspid Regurgitation
Interventions: Not listed
Lead sponsor: Woolsthorpe Technologies, LLC; Industry
Eligibility: 18 Years to 95 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 3
States / cities: Nashville, Tennessee • Houston, Texas

Conditions: Coronary Artery Bypass Grafting, Heart Diseases, Heart Valve Diseases
Interventions: Not listed
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2007
U.S. locations: 1
States / cities: New York, New York

Conditions: Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases
Interventions: DUO Transcatheter Tricuspid Coaptation Valve System; Device
Lead sponsor: CroiValve Limited; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 14
States / cities: Phoenix, Arizona • Thousand Oaks, California • Atlanta, Georgia + 11 more

Conditions: Tricuspid Valve Insufficiency, Right Heart Failure, Heart Failure
Interventions: Tricuspid valve repair or replacement, Medical management of tricuspid regurgitation; Procedure · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tricuspid Valve Regurgitation
Interventions: Edwards FORMA Tricuspid Transcatheter Repair System; Device
Lead sponsor: Edwards Lifesciences; Industry
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2023
U.S. locations: 5
States / cities: Los Angeles, California • Atlanta, Georgia • Rochester, Minnesota + 2 more

Conditions: Tricuspid Regurgitation
Interventions: Laplace TTVR System; Device
Lead sponsor: Laplace Interventional, Inc; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2032
U.S. locations: 10
States / cities: Tucson, Arizona • San Francisco, California • Atlanta, Georgia + 7 more

Conditions: Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency
Interventions: Contour 3D® implant for tricuspid valve repair, Tri-Ad® implant for tricuspid valve repair; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 3
States / cities: Aventura, Florida • Ann Arbor, Michigan • Asheville, North Carolina

Search by objective public record fields.

The TRICURE US IDE Pivotal Study

NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study

CorMatrix Cor TRICUSPID ECM Valve Replacement Study

A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease

Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI

Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients

Clinical Study of the inQB8 TTVR System (The MonarQ Study)

TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (TRINITY-US)

Impact of Vitamin C on Endothelial Function and Exercise Capacity in Fontan-Palliated Patients

TTVR Early Feasibility Study

TRIFORMIS RESILIA Real-world Study Assessing Safety and Performance (TRIBLAZE Study)

Biomarkers in Aortic Stenosis - B.A.S.S.

Structural Heart and Valve Network PROSPECTIVE Registry

Early Feasibility Study of 3830 Lead Implantation Via the Middle Cardiac Vein in Patients With Prior or Planned Tricuspid Valve Intervention

Edwards CLASP TR EFS

Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions

TRILUMINATE Pivotal Trial

Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000

The Short Form-36: Pre- Versus Post-Surgical Administration in Cardiac Surgery Patients

EFS of the DUO System for Tricuspid Regurgitation

Treatment of Tricuspid Valve Regurgitation in Patients Undergoing Left Ventricular Assist Device Implantation Study

Early Feasibility Study of the Edwards FORMA Tricuspid Transcatheter Repair System

Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System

Contour 3D®/TriAd® Tricuspid Annuloplasty Ring Post-Market Clinical Trial