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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:46 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Tricuspid Valve Regurgitation Clear all

Conditions: Tricuspid Regurgitation (TR)
Interventions: TRiCares Topaz TTVR System, Edwards EVOQUE TTVR System; Device
Lead sponsor: TRiCares; Industry
Eligibility: 18 Years and older
Enrollment: 831 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2035
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Tricuspid Valve Insufficiency
Interventions: TRAIPTA (Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty); Device
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 21 Years to 100 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 2
States / cities: Atlanta, Georgia • Roslyn, New York

Conditions: Tricuspid Valve Regurgitation, Non-rheumatic, Mitral Valve Regurgitation
Interventions: Not listed
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: Not listed
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
Interventions: Application of positive-end-expiratory pressure; Other
Lead sponsor: Northwell Health; Other
Eligibility: 3 Months to 18 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Tricuspid Valve Regurgitation
Interventions: Transcatheter Tricuspid Valve Replacement; Device
Lead sponsor: inQB8 Medical Technologies, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 6
States / cities: Los Angeles, California • Thousand Oaks, California • Atlanta, Georgia + 3 more

Conditions: Tricuspid Regurgitation (TR)
Interventions: Transcatheter Tricuspid Valve Intervention; Device
Lead sponsor: Jenscare Innovation Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2030
U.S. locations: 3
States / cities: Los Angeles, California • Detroit, Michigan • New York, New York

Conditions: Tricuspid Regurgitation
Interventions: Intrepid™ TTVR System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2031
U.S. locations: 20
States / cities: Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 16 more

Conditions: Aortic Stenosis, Disorder of Prosthetic Cardiac Valve, Aortic Valve Insufficiency, Mitral Valve Insufficiency, Hypertrophic Cardiomyopathy, Tricuspid Valve Insufficiency
Interventions: Blood Draw; Procedure
Lead sponsor: Mayo Clinic; Other
Eligibility: 21 Years and older
Enrollment: 378 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2020
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Mitral Valve Regurgitation, Heart Failure, Heart Valve Disease, Tricuspid Valve Regurgitation, Aortic Valve Stenosis
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: 18 Years to 99 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Tricuspid Regurgitation
Interventions: Edwards PASCAL Transcatheter Valve Repair System; Device
Lead sponsor: Edwards Lifesciences; Industry
Eligibility: 18 Years and older
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 15
States / cities: Los Angeles, California • Atlanta, Georgia • Chicago, Illinois + 11 more

Conditions: Valvular Heart Disease
Interventions: HBCR hands-off, HBCR interactive; Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Tricuspid Regurgitation
Interventions: TriClipTM Device; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 18 Years and older
Enrollment: 572 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 63
States / cities: Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 51 more

Conditions: Congestive Heart Failure, Ischemic Cardiomyopathy, Mitral Valve Prolapse, Mitral Regurgitation, Aortic Valve Disease, Tricuspid Regurgitation
Interventions: Not listed
Lead sponsor: Woolsthorpe Technologies, LLC; Industry
Eligibility: 18 Years to 95 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008
U.S. locations: 3
States / cities: Nashville, Tennessee • Houston, Texas

Conditions: Tricuspid Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases
Interventions: DUO Transcatheter Tricuspid Coaptation Valve System; Device
Lead sponsor: CroiValve Limited; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2029
U.S. locations: 14
States / cities: Phoenix, Arizona • Thousand Oaks, California • Atlanta, Georgia + 11 more

Conditions: Tricuspid Valve Insufficiency, Right Heart Failure, Heart Failure
Interventions: Tricuspid valve repair or replacement, Medical management of tricuspid regurgitation; Procedure · Other
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Tricuspid Valve Regurgitation
Interventions: Edwards FORMA Tricuspid Transcatheter Repair System; Device
Lead sponsor: Edwards Lifesciences; Industry
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2023
U.S. locations: 5
States / cities: Los Angeles, California • Atlanta, Georgia • Rochester, Minnesota + 2 more

Conditions: Tricuspid Regurgitation
Interventions: Laplace TTVR System; Device
Lead sponsor: Laplace Interventional, Inc; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2032
U.S. locations: 10
States / cities: Tucson, Arizona • San Francisco, California • Atlanta, Georgia + 7 more

Conditions: Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency
Interventions: Contour 3D® implant for tricuspid valve repair, Tri-Ad® implant for tricuspid valve repair; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 3
States / cities: Aventura, Florida • Ann Arbor, Michigan • Asheville, North Carolina

Conditions: Tricuspid Regurgitation (TR)
Interventions: TTVI with LuX-Valve Plus System, TTVI with EVOQUE; Device
Lead sponsor: Jenscare Innovation Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 680 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2038
U.S. locations: 2
States / cities: Naples, Florida • The Bronx, New York

Conditions: Valvular Heart Disease
Interventions: Not listed
Lead sponsor: Montefiore Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 330,570 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2019
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Tricuspid Regurgitation Functional
Interventions: CI Percutaneous Ring Annuloplasty System; Device
Lead sponsor: Cardiac Implants LLC; Industry
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 2
States / cities: Hackensack, New Jersey • New York, New York

Conditions: Severe Tricuspid Regurgitation
Interventions: Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System, Edwards EVOQUE Tricuspid Valve Replacement (TTVR) System; Device
Lead sponsor: Medtronic Cardiovascular; Industry
Eligibility: 18 Years and older
Enrollment: 1,186 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2041
U.S. locations: 20
States / cities: Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 16 more

Conditions: Coronary Artery Disease, Coronary Artery Stenoses, Valve Regurgitation, Mitral, Valve Regurgitation, Tricuspid
Interventions: Exparel Injectable Product, Bupivacaine Hydrochloride; Drug
Lead sponsor: Kathirvel Subramaniam; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Cardiac Surgery, Tricuspid Valve Regurgitation
Interventions: Tricuspid valve repair, Mitral surgery alone; Procedure · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years and older
Enrollment: 57 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2017
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

The TRICURE US IDE Pivotal Study

NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study

Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI

Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients

Clinical Study of the inQB8 TTVR System (The MonarQ Study)

TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (TRINITY-US)

TTVR Early Feasibility Study

Biomarkers in Aortic Stenosis - B.A.S.S.

Structural Heart and Valve Network PROSPECTIVE Registry

Edwards CLASP TR EFS

Home-Based Cardiac Rehabilitation Using a Novel Mobile Health Exercise Regimen Following Transcatheter Heart Valve Interventions

TRILUMINATE Pivotal Trial

Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000

EFS of the DUO System for Tricuspid Regurgitation

Treatment of Tricuspid Valve Regurgitation in Patients Undergoing Left Ventricular Assist Device Implantation Study

Early Feasibility Study of the Edwards FORMA Tricuspid Transcatheter Repair System

Early Feasibility Study (EFS) Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System

Contour 3D®/TriAd® Tricuspid Annuloplasty Ring Post-Market Clinical Trial

Pivotal Trial to Evaluate TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (The TRINITY Pivotal Trial)

The Bronx-Valve Registry

Early Feasibility Study of the Cardiac Implants Percutaneous Ring Annuloplasty System

Transcatheter Tricuspid Valve Replacement With the Medtronic Intrepid™ Transcatheter Tricuspid Valve Replacement (TTVR) System in Severe Tricuspid Regurgitation

Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride

Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Miral Operation