Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Jul 23, 2026, 6:31 PM EDT

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Showing 1–24 of 249 matching trials from the live ClinicalTrials.gov search.
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Conditions
Type 2 Diabetes
Interventions
Intensive education and lifestyle support, Standard of Care control group
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Frailty, Weight, Body, Type 2 Diabetes
Interventions
Lifestyle App, Look AHEAD behavior lifestyle intervention, Abbreviated Look AHEAD behavior lifestyle intervention
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
65 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Glucose Intolerance, Diabetes Mellitus, Type 2
Interventions
exercise and diet
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
40 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
1994 – 1999
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Pre-Gestational Diabetes, Type2diabetes, Pregnancy in Diabetic, Pregnancy, High Risk, Gestational Diabetes, Gestational Diabetes Mellitus in the Puerperium
Interventions
Immediate inpatient postpartum OGTT, Standard of care 4-12 week postpartum OGTT
Diagnostic Test
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Results available

Cryovagotomy Diabetes Trial

NCT04276051
Conditions
Diabetes Type 2, Diabetes Mellitus, Obesity
Interventions
Cryoablation of the Vagus Nerve, Lifestyle Intervention
Device · Behavioral
Lead sponsor
Emory University
Other
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Atlanta, Georgia • Johns Creek, Georgia
Conditions
Gestational Diabetes, Type 2 Diabetes
Interventions
Glucose tolerance test (2 hour), Active Comparator
Diagnostic Test · Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Metabolic Health on Sperm Epigenetic Marks in Humans

NCT03860558
Conditions
Overweight, Type 2 Diabetes Mellitus, Type 1 Diabetes Mellitus
Interventions
Lifestyle Intervention, No Intervention
Other
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Type 2 Diabetes, Mental Health Issue, Quality of Life, Weight Loss
Interventions
CBT-based lifestyle intervention
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
35 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Santa Barbara, California
Conditions
Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Type 2, Diabetes Mellitus, Coronary Disease
Interventions
Anti-hyperglycemic Agents, Anti-hypertensive Agents, Blinded fenofibrate or placebo plus simvastatin
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
40 Years to 79 Years
Enrollment
10,251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2012
U.S. locations
6
States / cities
Minneapolis, Minnesota • New York, New York • Winston-Salem, North Carolina + 3 more
Recruiting Not applicable Interventional

Food as Medicine for HIV and Diabetes

NCT05026723
Conditions
Diabetes Mellitus, Type 2, HIV Infections, PreDiabetes
Interventions
MTM + ILI, Standard MTM
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Recreational Basketball to Increase Participation in Diabetes Prevention

NCT05066542
Conditions
Type 2 Diabetes, PreDiabetes
Interventions
NDPP + Basketball (BB), NDPP Standard of Care SOC
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 44 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Diabetes, Nutrition
Interventions
CGM Device
Device
Lead sponsor
Sutter Health
Other
Eligibility
18 Years to 89 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Santa Barbara, California
Conditions
Type 2 Diabetes Mellitus, Obesity
Interventions
Allergan Adjustable Gastric Band Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Band Group, Roux-en-Y Gastric Bypass (RYGB) Surgery, Intensive Medical Diabetes & Weight Management (Why WAIT) - Bypass Group
Device · Other · Procedure
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
21 Years to 65 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts
Conditions
Diabete Type 2, Disability Physical
Interventions
AI4DM, Attention-control
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Type2 Diabetes
Interventions
FareWell Program
Behavioral
Lead sponsor
FareWell
Industry
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Francisco, California
Conditions
Prediabetes, Type 2 Diabetes, Obesity
Interventions
Intensive Lifestyle Intervention (ILI)
Behavioral
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 65 Years
Enrollment
223 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Memphis, Tennessee
Conditions
Diabetes Mellitus, Type 2 Diabetes, Obesity
Interventions
WW Intervention, Usual Care
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 69 Years
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Stanford, California • Baton Rouge, Louisiana • Winston-Salem, North Carolina
Completed Phase 1 Interventional Accepts healthy volunteers

Mechanism of Insulin-Resistant in Lean Non-Diabetics

NCT00970099
Conditions
Insulin Resistance, Insulin Sensitivity, Type 2 Diabetes
Interventions
exercise, Non exercise
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
20 Years to 50 Years
Enrollment
149 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Family Diabetes Prevention Program Pilot Study

NCT05358444
Conditions
PreDiabetes, Overweight and Obesity, Type 2 Diabetes, Overweight, Childhood, Obesity, Childhood, Lifestyle, Healthy
Interventions
National Diabetes Prevention Program Lifestyle Intervention (DPP), Family Diabetes Prevention Program (Family DPP)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
5 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Results available

An Educational Intervention for Type 2 Diabetes Patients

NCT01671345
Conditions
Diabetes Mellitus
Interventions
Intervention Video, Control
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
169 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Completed Not applicable Interventional Accepts healthy volunteers

Native Hawaiian Diabetes Intervention Program

NCT00006165
Conditions
Diabetes Mellitus, Type 2
Interventions
'Ohana (Family) Support Lifestyle Intervention
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
30 Years and older
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Honolulu, Hawaii
Not listed Phase 3 Interventional Results available

Diabetes Prevention Program Outcomes Study

NCT00038727
Conditions
Diabetes Mellitus, Cancer, CVD
Interventions
DPPOS Group Lifestyle, Metformin, DPPOS Boost Lifestyle, Intensive Lifestyle Group Session
Behavioral · Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
25 Years and older
Enrollment
2,779 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2025
U.S. locations
1
States / cities
Rockville, Maryland
Conditions
Obesity, Type 2 Diabetes
Interventions
laparoscopic roux en y gastric bypass operation, medical management
Procedure · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 60 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting Not applicable Interventional

PILI 'Āina Household

NCT06526273
Conditions
Type 2 Diabetes, Hypertension, Dyslipidemias, Overweight and Obesity
Interventions
PILI 'Āina, Control
Behavioral · Other
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Honolulu, Hawaii • Kapolei, Hawaii