Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 23, 2026, 4:46 PM EDT

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Showing 1–24 of 125 matching trials from the live ClinicalTrials.gov search.
Conditions
Obesity, Type 2 Diabetes Prevention, Executive Function (Cognition)
Interventions
Aerobic exercise program
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
7 Years to 11 Years
Enrollment
222 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2007
U.S. locations
1
States / cities
Augusta, Georgia
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Optimizing Lifestyles Through Increased Vegetable-rich Eating Pilot Study

NCT07509502
Conditions
Type 2 Diabetes (T2DM), Obesity & Overweight
Interventions
Dietary Intervention Teaching Kitchen (TK) Classes, Food is Medicine Grocery Provision (FiM)
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Conditions
Insulin Resistance, Depression, Depressive Disorder, Mood Disorders, Mental Disorder in Adolescence, Hyperinsulinism, Glucose Metabolism Disorders, Metabolic Disease
Interventions
Cognitive-Behavioral Therapy followed by Exercise Training, Exercise Training followed by Cognitive-Behavioral Therapy, Cognitive-Behavioral Therapy Only, Exercise Training Only
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
2
States / cities
Aurora, Colorado • Fort Collins, Colorado
Conditions
Type 2 Diabetes, Overweight, ASCVD
Interventions
Dulaglutide, Semaglutide, Tirzepatide, Sitagliptin
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60,000 participants
Timeline
2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Call-2-Health: Preventing Type II Diabetes

NCT01827826
Conditions
Diabetes Mellitus, Type 2
Interventions
Telephonic intervention to prevent Diabetes Mellitus, Type 2
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
40 Years to 74 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Active, not recruiting Not applicable Interventional

The YMCA Healthy Lifestyle Program for Prediabetes

NCT06841796
Conditions
PreDiabetes
Interventions
Real time continuous glucose monitor (Stelo)
Device
Lead sponsor
Young Men's Christian Association of the Blue Water Area
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Port Huron, Michigan
Conditions
Obesity, Overweight, Diabetes
Interventions
Cell Phone, Weekly access to interactive web site, Group
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
12 Years to 16 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
La Jolla, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Patient-Centered Strategy for Improving Diabetes Prevention in Urban American Indians

NCT02266576
Conditions
Diabetes Mellitus, Type 2, Metabolic Syndrome, Insulin Resistance
Interventions
Standard DPP, Enhanced DPP
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
21 Years and older
Enrollment
207 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
2
States / cities
San Jose, California • Stanford, California
Completed Phase 3 Interventional Results available

Cardiovascular Inflammation Reduction Trial

NCT01594333
Conditions
Cardiovascular Disease
Interventions
Methotrexate, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
4,786 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
404
States / cities
Birmingham, Alabama • Fort Payne, Alabama • Guntersville, Alabama + 296 more
Recruiting Not applicable Interventional Accepts healthy volunteers

PATHS-UP Health Behavior Self-monitoring Mobile App for Adolescents

NCT06959901
Conditions
Obesity and Diabetes Mellitus, Type 2, Diabetes Prevention
Interventions
PATHS-UP Mobile Phone Application
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Conditions
Obesity, Type 2 Diabetes
Interventions
Reach-Out Program, nutritional and exercise program, Reach-In Program, standard of care
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
9 Years to 65 Years
Enrollment
131 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Prediabetes / Type 2 Diabetes
Interventions
Video Diabetes Education, In person or virtual diabetes education
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Conditions
Hyperglycemia
Interventions
Sitagliptin, Placebo, Regular Human Insulin, Insulin glargine, Supplemental insulin (Insulin lispro), Supplemental insulin (Insulin aspart)
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 80 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
3
States / cities
Atlanta, Georgia
Conditions
Diabetes Mellitus, Type 2
Interventions
Pharmacist review of therapy
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 75 Years
Enrollment
239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Trenton, New Jersey
Conditions
Diabetes Mellitus, Type 2
Interventions
Diabetes Prevention Program, Health Mindset modified diabetes prevention program
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years to 50 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Browning, Montana
Conditions
Prediabetic State
Interventions
Rimonabant, Placebo (for Rimonabant)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
35 Years to 75 Years
Enrollment
2,420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Recreational Basketball to Increase Participation in Diabetes Prevention

NCT05066542
Conditions
Type 2 Diabetes, PreDiabetes
Interventions
NDPP + Basketball (BB), NDPP Standard of Care SOC
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years to 44 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Diabetes Mellitus, Type 2, PreDiabetes
Interventions
Mobile 360° Video intervention, Motivation and Problem Solving (MAPS), Risk notification/education
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 89 Years
Enrollment
818 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
PreDiabetes, Prediabetic State, Overweight and Obesity
Interventions
PreventT2 (Individual intervention), PreventT2 Together (Couple-based intervention)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Hypertension, Dyslipidemias, Type 2 Diabetes, HIV-1-infection
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Charlotte, North Carolina • Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Getting in Balance: A Workplace Diabetes Prevention Intervention Trial

NCT02589873
Conditions
Diabetes Mellitus, Type 2, Overweight, Obesity
Interventions
In-Person Diabetes Prevention Program, Online Diabetes Prevention Program
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Results available

Evaluating a Type 2 Diabetes Prevention Program

NCT05822648
Conditions
Type 2 Diabetes, PreDiabetes
Interventions
Project Health, Educational Video Control
Behavioral · Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Stanford, California
Completed Not applicable Interventional Accepts healthy volunteers

Middle-School Based Primary Prevention Trial of Type 2 Diabetes

NCT00458029
Conditions
Type 2 Diabetes
Interventions
integrated program of nutrition, activity, behavior, and promotion
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
10 Years to 16 Years
Enrollment
4,603 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
8
States / cities
Irvine, California • Rockville, Maryland • Chapel Hill, North Carolina + 5 more
Conditions
Prediabetes / Type 2 Diabetes
Interventions
Metformin, GLP-1A, MED
Drug · Dietary Supplement
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Stanford, California