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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Underage Drinking Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Feedback, Reflection and Morning Evaluation

NCT05509218
View directory record Official record
Conditions
Youth Drinking, Alcohol Drinking
Interventions
Mobile-delivered personalized feedback
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 29 Years
Enrollment
152 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 4, 2026, 1:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Primary Connections for Youth and Families

NCT05964010
View directory record Official record
Conditions
Substance Use
Interventions
Standard Screening, Standard Psychoeducation, Standard Brief Negotiated Interview (BNI), Standard Referral to Treatment (RT), Family Screening, Family Psychoeducation, Family Brief Negotiated Interview (BNI), Family Facilitated Conversation (FC) & Referral to Treatment (RT)
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
12 Years to 17 Years
Enrollment
2,300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 4, 2026, 1:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)

NCT06699251
View directory record Official record
Conditions
Adolescent Drinking, Cannabis Use
Interventions
Chat, Enhanced Usual Care
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 19 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Commerce, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alcohol Intervention for First Year College Students

NCT03750838
View directory record Official record
Conditions
Underage Alcohol Use
Interventions
Text Messaging Intervention
Behavioral
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years to 19 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jan 18, 2024 · Synced Sep 4, 2026, 1:47 PM EDT
Enrolling by invitation Not applicable Interventional

Optimizing and Advancing SBIRT in Schools

NCT06206161
View directory record Official record
Conditions
Adolescent Drinking, Adolescent Substance Use, Risk Behavior, Health
Interventions
Indicated Prevention, Clinical Staff, Selective Prevention, Expanded Paraprofessional Workforce
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 19 Years
Enrollment
21,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional

A Brief Intervention

NCT01632176
View directory record Official record
Conditions
Dating Violence, Dating Abuse
Interventions
Brief, motivational interview and one booster session
Behavioral
Lead sponsor
Boston University
Other
Eligibility
15 Years to 19 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2017 · Synced Sep 4, 2026, 1:47 PM EDT
Recruiting Not applicable Interventional

Centralized Virtual SBIRT for Pediatric Primary Care

NCT06486688
View directory record Official record
Conditions
Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Interventions
Centralized Virtual SBIRT
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 17 Years
Enrollment
22,320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2024 · Synced Sep 4, 2026, 1:47 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Examining an Intervention to Reduce High School Drinking

NCT07086508
View directory record Official record
Conditions
Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
Interventions
e-CHECKUP TO GO (eCTG), e-Parent Intervention
Behavioral
Lead sponsor
Binghamton University
Other
Eligibility
15 Years to 65 Years
Enrollment
2,532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Binghamton, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2026 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brief Intervention to Prevent Alcohol Socialization (BIPAS Alcohol)

NCT05520333
View directory record Official record
Conditions
Alcohol Drinking, Adolescent, Drinking Behavior, Drinking, Alcohol, Adolescent Behavior
Interventions
BIPAS Alcohol
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2025 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Revolutionizing Normative Re-education

NCT04356261
View directory record Official record
Conditions
College Drinking, Underage Drinking, Alcohol Use Disorder
Interventions
Gamified Personalized Normative Feedback
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
18 Years to 20 Years
Enrollment
1,143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Community-Based Strategy for Preventing Underage Drinking

NCT02448134
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Youth Access
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 19 Years
Enrollment
7,379 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 15, 2020 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Parental Research on Interventions for Social Media

NCT04333966
View directory record Official record
Conditions
Underage Drinking
Interventions
Interactive Social Networking Site Parent Based Intervention, Active Control
Behavioral
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
15 Years and older
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project U Connect - Optimizing Brief Alcohol Intervention for Underage Drinkers in the ER

NCT01051141
View directory record Official record
Conditions
Alcohol Misuse
Interventions
Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 20 Years
Enrollment
870 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project MADD - NIH Underage DUI and Ride

NCT03506880
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen
Interventions
MADD Materials, Surgeon General Materials
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,352 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alcohol and Health: Personalized Feedback

NCT03337438
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Consumption, Youth
Interventions
Personalized Feedback Intervention with Values, Personalized Feedback Intervention Traditional
Other
Lead sponsor
Oklahoma State University
Other
Eligibility
18 Years and older
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Topiramate on Adolescent Alcohol Use: Efficacy and Mechanisms

NCT01641445
View directory record Official record
Conditions
Alcohol Drinking
Interventions
Topiramate, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
14 Years to 24 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Healthy Families Bright Futures Program

NCT06309134
View directory record Official record
Conditions
Alcohol Drinking, Violence in Adolescence
Interventions
Healthy Families Bright Futures Program
Behavioral
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
15 Years to 18 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 4, 2026, 1:47 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Efficacy of the Expectancy Challenge Alcohol Literacy Curriculum on Reducing College Student Alcohol Use and Harms

NCT05616247
View directory record Official record
Conditions
Alcohol Use, Underage, Harmful; Use, Alcohol
Interventions
ECALC, ECALC Plus Weekly Boosters
Behavioral
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care

NCT04450966
View directory record Official record
Conditions
Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
Interventions
Computer-facilitated Screening and Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 17 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Itasca, Illinois • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Intervention for Teen Drinking in the ER

NCT01229748
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Standard Care, Multidimensional Family Therapy, Family Motivational Interviewing Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 18 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
3
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

PARTNER Recruitment and Brief Intervention Pilot Study

NCT00735956
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Counseling
Behavioral
Lead sponsor
Duke University
Other
Eligibility
12 Years to 20 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 22, 2010 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

NCT04160754
View directory record Official record
Conditions
Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
Interventions
Mindfulness Based Relapse Prevention, Control (CTL)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 26 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of a Web-Based Alcohol Intervention for High School Students

NCT03613818
View directory record Official record
Conditions
Underage Drinking
Interventions
eCHECKUP TO GO
Behavioral
Lead sponsor
Boise State University
Other
Eligibility
16 Years to 18 Years
Enrollment
311 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Sep 4, 2026, 1:47 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Neuroscience-Informed Treatment Development for Adolescent Alcohol Use

NCT03238300
View directory record Official record
Conditions
Alcohol Drinking, Control
Interventions
N-Acetylcysteine, Placebo Oral Capsule
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
15 Years to 19 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Sep 4, 2026, 1:47 PM EDT