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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Underage Drinking Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Strategies: Motivational Interviewing/Psychoeducation

NCT03458299
View directory record Official record
Conditions
Alcohol Use, Underage, Substance Use, Underage Drinking
Interventions
Motivational Interviewing, Psychoeducation
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
13 Years to 20 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Valley Center, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Jul 21, 2026, 11:46 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based College for Young Adults

NCT04733300
View directory record Official record
Conditions
Depressive Symptoms, Loneliness, Sedentary Behavior, Mindfulness, Physical Activity, Diet, Sleep, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College for Young Adults, Health Education for Young Adults
Behavioral · Other
Lead sponsor
Eric Loucks
Other
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Jul 21, 2026, 11:46 AM EDT
Recruiting Not applicable Interventional

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

NCT06593652
View directory record Official record
Conditions
Alcohol Use, Adolescent, Mild Alcohol Use Disorder, Mild Substance Use Disorder
Interventions
Teen Intervene - Adolescent Only, Teen Intervene with Caregiver Session, Family Check Up
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
12 Years to 17 Years
Enrollment
615 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Examining an Intervention to Reduce High School Drinking

NCT07086508
View directory record Official record
Conditions
Underage Drinking, Drinking, Teen, Adolescent Alcohol Use
Interventions
e-CHECKUP TO GO (eCTG), e-Parent Intervention
Behavioral
Lead sponsor
Binghamton University
Other
Eligibility
15 Years to 18 Years
Enrollment
2,532 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Binghamton, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Digitally Prompted Parenting: A Text Message Parent-Based Alcohol Intervention for Incoming College Students

NCT06861660
View directory record Official record
Conditions
Underage Drinking
Interventions
Digitally Prompted Parenting, Active Control
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
17 Years to 20 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project U Connect - Optimizing Brief Alcohol Intervention for Underage Drinkers in the ER

NCT01051141
View directory record Official record
Conditions
Alcohol Misuse
Interventions
Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET)
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years to 20 Years
Enrollment
870 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Facilitating Adolescent Self-Change for Alcohol Problems

NCT01690026
View directory record Official record
Conditions
Underage Drinking
Interventions
Motivation interviewing based brief intervention, Standard Intervention
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
14 Years to 19 Years
Enrollment
1,209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
3
States / cities
Miami, Florida • Minneapolis, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 21, 2026, 11:46 AM EDT
Recruiting Not applicable Interventional

Brief Motivational Interviewing +/- Mindfulness Training for Adolescent Alcohol Use in Pediatric Primary Care

NCT07059078
View directory record Official record
Conditions
Adolescent Alcohol Use
Interventions
Brief Motivational Interviewing-based Alcohol Intervention, Smartphone App-delivered Mindfulness Training
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
12 Years to 17 Years
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
13
States / cities
Baltimore, Maryland • Belcamp, Maryland • Bowie, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jul 21, 2026, 11:46 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Native Spirit: Significant Aim 3: Intervention

NCT06785311
View directory record Official record
Conditions
Substance Use, Self Esteem, Youth Drinking, Prevention, Suicide
Interventions
Native Spirit After-School Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
12 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Scottsdale, Arizona • Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

2 College Truths and 1 Lie

NCT06576011
View directory record Official record
Conditions
Underage Drinking
Interventions
Gamified Social Norms Marketing Campaign, Social Norms Marketing Campaign
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
18 Years to 20 Years
Enrollment
392 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

NCT04160754
View directory record Official record
Conditions
Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
Interventions
Mindfulness Based Relapse Prevention, Control (CTL)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 26 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

PARTNER Recruitment and Brief Intervention Pilot Study

NCT00735956
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Counseling
Behavioral
Lead sponsor
Duke University
Other
Eligibility
12 Years to 20 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 22, 2010 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness-Based College: Stage 1

NCT03124446
View directory record Official record
Conditions
Diet Habit, Physical Activity, Sleep, Loneliness, Emotional Regulation, Alcohol Consumption, Youth, Stress, Psychological
Interventions
Mindfulness-Based College, Enhanced Usual Care Control
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 28 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 11, 2019 · Synced Jul 21, 2026, 11:46 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Parent Intervention to Reduce College Student Drinking and Consequences

NCT04247191
View directory record Official record
Conditions
Underage Drinking, Driving Under the Influence, Drinking, Teen, Drinking, College
Interventions
P-Chat+, PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
2,061 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally Enhancing a Motivational Interviewing Intervention For Latinx Adolescents

NCT03947177
View directory record Official record
Conditions
Underage Alcohol Use, Smoking, Non-Tobacco Products
Interventions
GMIT+
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
10 Years to 16 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 29, 2022 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

REAL Parenting Alcohol and Substance Use App

NCT03932097
View directory record Official record
Conditions
Underage Drinking, Alcohol Use, Underage
Interventions
REAL Parenting, Active Control Materials
Behavioral · Other
Lead sponsor
Real Prevention, LLC
Industry
Eligibility
15 Years to 18 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Clifton, New Jersey
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project e-PBI+ - Parent Intervention to Reduce College Student Drinking and Cannabis Use

NCT05345951
View directory record Official record
Conditions
Underage Drinking, Cannabis Use, Drinking, Teen, Drinking, College, College Drinking, Teen Drinking
Interventions
e-PBI
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 19 Years
Enrollment
1,980 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Family Intervention for Teen Drinking in the ER

NCT01229748
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Standard Care, Multidimensional Family Therapy, Family Motivational Interviewing Intervention
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 18 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
3
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 30, 2015 · Synced Jul 21, 2026, 11:46 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effectiveness of Brief Intervention in Primary Care for Diverse Young People (Chat)

NCT06699251
View directory record Official record
Conditions
Adolescent Drinking, Cannabis Use
Interventions
Chat, Enhanced Usual Care
Behavioral
Lead sponsor
RAND
Other
Eligibility
12 Years to 19 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Commerce, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Norms Re-education to Promote Engagement in Parent-based Interventions

NCT06871982
View directory record Official record
Conditions
Underage Drinking
Interventions
PNF+ PBI, SNMC+ PBI, PH+ PBI
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
17 Years to 20 Years
Enrollment
2,040 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 21, 2026, 11:46 AM EDT
Recruiting Not applicable Interventional

Centralized Virtual SBIRT for Pediatric Primary Care

NCT06486688
View directory record Official record
Conditions
Adolescent Alcohol Use, Mental Health Issue, Alcohol Related Disorders, Adolescents
Interventions
Centralized Virtual SBIRT
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 17 Years
Enrollment
22,320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2024 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Experimental Test of Facebook Social Drinking Norms on Adolescent Alcohol Use

NCT03159286
View directory record Official record
Conditions
Feedback, Psychological, Underage Alcohol Use, Risk-Taking
Interventions
Abstainer, Abstainer + User, Control
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
15 Years to 20 Years
Enrollment
306 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 20, 2019 · Synced Jul 21, 2026, 11:46 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of Global Smart Drinking Goals Initiative

NCT03262259
View directory record Official record
Conditions
Binge Drinking, Underage Drinking, Drinking and Driving, Alcohol-Related Harms
Interventions
GSDG multi-component intervention
Behavioral
Lead sponsor
HBSA
Other
Eligibility
12 Years and older
Enrollment
36,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
1
States / cities
Calverton, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2025 · Synced Jul 21, 2026, 11:46 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adolescent Substance Use Prevention Intervention Research Study in Pediatric Primary Care

NCT04450966
View directory record Official record
Conditions
Heavy Drinking, Driving Under the Influence, Riding With Driver Under the Influence
Interventions
Computer-facilitated Screening and Brief Intervention
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 17 Years
Enrollment
169 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
3
States / cities
Itasca, Illinois • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 21, 2026, 11:46 AM EDT