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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Unicompartmental Knee Arthroplasty Clear all
Enrolling by invitation Not applicable Interventional

Cemented vs. Cementless Unicompartmental Knee Arthroplasty

NCT05616884
View directory record Official record
Conditions
Partial Knee Replacement
Interventions
Cementless fixation
Procedure
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Jul 22, 2026, 5:55 AM EDT
Enrolling by invitation No phase listed Observational

Exactech Knee Systems Post Market Clinical Follow-up

NCT07107581
View directory record Official record
Conditions
Knee Arthroplasty, Total, Partial Knee Replacement
Interventions
Prospective / Subjects Knee Arthroplasty, Retrospective to Prospective, Retrospective Only Subjects
Device
Lead sponsor
Exactech
Industry
Eligibility
18 Years and older
Enrollment
1,879 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2036
U.S. locations
1
States / cities
DeLand, Florida
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Jul 22, 2026, 5:55 AM EDT
Not listed Not applicable Interventional

Trial of Unicompartmental Versus Total Knee Arthroplasty

NCT03385759
View directory record Official record
Conditions
Osteo Arthritis Knee
Interventions
Unicompartmental knee arthroplasty, Total knee arthroplasty
Procedure
Lead sponsor
Anderson Orthopaedic Research Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Chicago, Illinois • Alexandria, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Jul 22, 2026, 5:55 AM EDT
Terminated Not applicable Interventional Results available

Triathlon® Partial Knee Replacement (PKR) Outcomes Study

NCT00966979
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
Triathlon PKR
Device
Lead sponsor
Stryker Orthopaedics
Industry
Eligibility
21 Years to 75 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
6
States / cities
Jacksonville, Florida • Egg Harbor, New Jersey • Buffalo, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Jul 22, 2026, 5:55 AM EDT
Active, not recruiting No phase listed Observational

Early Outcomes of MAKO Medial Unicompartmental Knee Arthroplasty

NCT05736601
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
focus motion knee brace
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
95 participants
Timeline
2022 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 22, 2026, 5:55 AM EDT
Active, not recruiting Not applicable Interventional

Prospective Randomized Study of Cementless vs Cemented UKA

NCT05377450
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Engage Partial Knee
Device
Lead sponsor
JIS Research Institute
Other
Eligibility
21 Years to 80 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New Albany, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Jul 22, 2026, 5:55 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

A Randomized Controlled Trial for Partial Knee Arthroplasty

NCT05037734
View directory record Official record
Conditions
Degenerative Joint Disease of Knee, Osteoarthritis, Traumatic Arthritis, Varus Deformity, Knee Pain Chronic
Interventions
Persona Partial Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional

Formal vs. Home-Based Physical Therapy After Unicompartmental Knee Arthroplasty

NCT02883998
View directory record Official record
Conditions
Osteoarthritis
Interventions
Outpatient Physical Therapy, Home Base Physical Therapy
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 10, 2018 · Synced Jul 22, 2026, 5:55 AM EDT
Completed No phase listed Observational Results available

Survivorship and Outcomes of Robot Assisted Medial Partial Knee Replacement

NCT01845597
View directory record Official record
Conditions
Unicompartmental Knee Arthroplasty
Interventions
MAKOplasty® medial UKA
Procedure
Lead sponsor
Northwest Surgical Specialists, Vancouver
Other
Eligibility
21 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Vancouver, Washington
Source: ClinicalTrials.gov public record
Updated Jul 12, 2023 · Synced Jul 22, 2026, 5:55 AM EDT
Not yet recruiting Phase 4 Interventional

Post-op Prednisone and Glucose Monitoring in TKA

NCT07630896
View directory record Official record
Conditions
Osteoarthritis, Unicompartmental Knee Arthroplasty, Total Hip Arthroplasty (THA)
Interventions
Prednisone, Continuous Glucose Monitor, InkWell Health Tattoos
Drug · Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) System

NCT04341948
View directory record Official record
Conditions
Postoperative Pain, Total Knee Replacement, Total Knee Arthroplasty, Partial Knee Replacement
Interventions
SPRINT Peripheral Nerve Stimulation (PNS) System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
10
States / cities
Little Rock, Arkansas • San Diego, California • Gainesville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Jul 22, 2026, 5:55 AM EDT
Not listed No phase listed Observational

Survivorship and Outcomes of Robotic-Arm Assisted Medial Unicompartmental Knee Arthroplasty

NCT03668717
View directory record Official record
Conditions
Osteoarthritis
Interventions
Robotic-arm assisted medical MCK implant
Device
Lead sponsor
St. Helena Hospital Coon Joint Replacement Institute
Other
Eligibility
21 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
1
States / cities
St. Helena, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Jul 22, 2026, 5:55 AM EDT
Completed No phase listed Observational

Study of Patient Outcomes 5 Years After Partial Knee Replacement

NCT01620892
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Not listed
Lead sponsor
Athens Orthopedic Clinic, P.A.
Other
Eligibility
18 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 9, 2019 · Synced Jul 22, 2026, 5:55 AM EDT
Active, not recruiting No phase listed Observational

Clinical Outcomes of Joint Arthroplasty

NCT03668691
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Robotic-arm assisted partial knee arthroplasty
Device
Lead sponsor
St. Helena Hospital Coon Joint Replacement Institute
Other
Eligibility
21 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2027
U.S. locations
1
States / cities
St. Helena, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Jul 22, 2026, 5:55 AM EDT
Completed No phase listed Observational

A Clinical Investigation of the Oxford® Meniscal Unicompartmental Knee System

NCT00578994
View directory record Official record
Conditions
Osteoarthritis, Avascular Necrosis
Interventions
Oxford® Meniscal Unicompartmental Knee System
Device
Lead sponsor
Biomet Orthopedics, LLC
Industry
Eligibility
18 Years and older
Enrollment
388 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2021
U.S. locations
6
States / cities
Schaumburg, Illinois • New Albany, Ohio • Cordova, Tennessee + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional

Doppler Ultrasound Following Unicondylar Knee Replacement to Determine the Incidence of Postoperative DVT

NCT02148757
View directory record Official record
Conditions
Number of Deep Venous Thrombosis (DVT)
Interventions
Doppler Ultrasound
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
Not listed
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Jul 22, 2026, 5:55 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Performance of MOTO Medial® Unicompartmental Knee Arthroplasty

NCT03211663
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic
Interventions
MOTO Medial® UKA
Device
Lead sponsor
Medacta USA
Industry
Eligibility
18 Years and older
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
5
States / cities
Lady Lake, Florida • Louisville, Kentucky • Billings, Montana + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Jul 22, 2026, 5:55 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Oxford Partial Knee Kinematics Gait Analysis Study

NCT01454908
View directory record Official record
Conditions
Medial Knee Compartment Arthritis
Interventions
Oxford Partial Knee
Device
Lead sponsor
The CORE Institute
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Sun City West, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 18, 2011 · Synced Jul 22, 2026, 5:55 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Fixed Bearing Versus Mobile Bearing Patient Satisfaction and Clinical Outcome Study

NCT02633085
View directory record Official record
Conditions
Osteoarthritis
Interventions
Fixed Bearing or Mobile Bearing UKA
Device
Lead sponsor
Medacta USA
Industry
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
1
States / cities
Leesburg, Florida
Source: ClinicalTrials.gov public record
Updated Mar 23, 2023 · Synced Jul 22, 2026, 5:55 AM EDT
Completed No phase listed Observational

Stated-Preferences in Knee Arthroplasty

NCT03058380
View directory record Official record
Conditions
Arthritis, Knee Osteoarthritis, Arthropathy of Knee
Interventions
Stated-Preferences Evaluation Instrument
Other
Lead sponsor
Duke University
Other
Eligibility
40 Years to 80 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Phase 4 Interventional Results available

Adductor Canal Block for Medial Compartment Knee Arthroplasty

NCT01818531
View directory record Official record
Conditions
Postoperative Analgesia, Medial Unicompartmental Knee Arthroplasty
Interventions
Adductor canal block, Lumbar plexus block
Drug
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2018 · Synced Jul 22, 2026, 5:55 AM EDT
Terminated No phase listed Observational

Multi-Center Study to Evaluate the ConforMIS iUni Knee Implant

NCT01117571
View directory record Official record
Conditions
Osteoarthritis
Interventions
iUni® Unicompartmental Knee Resurfacing Device
Device
Lead sponsor
Restor3D
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2023
U.S. locations
8
States / cities
Little Rock, Arkansas • La Quinta, California • Monterey, California + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 24, 2023 · Synced Jul 22, 2026, 5:55 AM EDT
Completed Not applicable Interventional Results available

A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform

NCT03737149
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
mymobility with Apple Watch
Other
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
6,559 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
26
States / cities
Fremont, California • Irvine, California • Redwood City, California + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 22, 2026, 5:55 AM EDT
Not listed Not applicable Interventional

Diagnostic Knee Needle Arthroscopy in Predicting Unicompartmental Knee Osteoarthritis

NCT05002387
View directory record Official record
Conditions
Arthroplasty, Replacement, Knee
Interventions
NanoScope™ Operative Arthroscopy (Arthrex, Inc)
Device
Lead sponsor
Albany Medical College
Other
Eligibility
18 Years to 89 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Albany, New York
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Jul 22, 2026, 5:55 AM EDT