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Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Unprotected Sex Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Young Adult Education on Alcohol & Health

NCT05620849
View directory record Official record
Conditions
Sexual Behavior, Alcohol Drinking, Condomless Sex
Interventions
Online program
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 24 Years · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional Results available

Brief Interventions in the Emergency Department for Alcohol and HIV/Sexual Risk

NCT01351389
View directory record Official record
Conditions
Alcohol Consumption, Unsafe Sex
Interventions
Brief Motivational Intervention (BMI), Brief Advice
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
3
States / cities
Pawtucket, Rhode Island • Providence, Rhode Island • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional

The Young Woman's Reach Project: Trial of an Intervention to Impact Contraceptive Behavior, Unintended Pregnancy, and Sexually Transmitted Infections (STIs) Among Adolescent Females

NCT00230880
View directory record Official record
Conditions
Contraceptive Behavior, Sexually Transmitted Diseases
Interventions
follow-up phone counseling
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2012 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of an Adapted STD Screening and Risk Reduction Intervention

NCT02513225
View directory record Official record
Conditions
Alcohol Use, Drug Use, Diagnostic Self Evaluation, Gonorrhea, Unprotected Sex, Chlamydia, Trichomonas
Interventions
Project EMPWR, Optimized Standard Care (OSC)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years to 49 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Fort Apache, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 26, 2023 · Synced Jul 21, 2026, 11:07 AM EDT
Completed No phase listed Observational

Evaluation of Implementation of the Phoenix PrEP (Pre-Exposure Prophylaxis) Access Project for Youth Aged 13-24

NCT03637322
View directory record Official record
Conditions
Unsafe Sex, IV Drug Usage
Interventions
Not listed
Lead sponsor
Phoenix Children's Hospital
Other
Eligibility
13 Years to 24 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional

An Evaluation of Re:MIX: a Teen Pregnancy Prevention Program With Young Parents as Peer Educators, EngenderHealth

NCT03114410
View directory record Official record
Conditions
Sexual Behavior, Unprotected Sex
Interventions
Re:MIX, a multi-layer comprehensive teen pregnancy prevention intervention aimed at reducing pregnancy and STIs among youth ages 13-17
Behavioral
Lead sponsor
Child Trends
Other
Eligibility
12 Years to 18 Years
Enrollment
621 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

No Excuses/Sin Buscar Excusas Intervention to Reduce Latino Men's HIV Risks

NCT00690690
View directory record Official record
Conditions
HIV Infections
Interventions
Video (group-delivered video-based intervention), HCT
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years to 49 Years · Male only
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2010 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Respecting the Circle of Life on Pregnancy Prevention Outcomes Among American Indian Adolescents

NCT02904629
View directory record Official record
Conditions
Sex, Unprotected Sex, Contraception, Alcohol Use, Drug Use, Pregnancy
Interventions
Respecting the Circle of Life (RCL), Control Program
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
11 Years and older
Enrollment
1,072 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 18, 2022 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Copper T380 IUD Versus Oral Levonorgestrel for Emergency Contraception vs. Plan B for Emergency Contraception

NCT00669396
View directory record Official record
Conditions
Pregnancy
Interventions
Copper T380 IUD, levonorgestrel
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
West Valley City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 21, 2014 · Synced Jul 21, 2026, 11:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)

NCT06096324
View directory record Official record
Conditions
Economic Hardship, Condomless Sex, Utilization, Health Care
Interventions
Job announcements plus HIV prevention text messages, educational sessions, economic resources, and mentoring., Job announcements
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 24 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Network Intervention for Reducing Sexual Risk for HIV With African American Men Who Have Sex With Men (AA MSM)

NCT00691041
View directory record Official record
Conditions
HIV Infections
Interventions
Unity in Diversity
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 12, 2012 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Project Power: An HIV Risk Reduction Intervention for Black Men Who Have Sex With Men and Women (BMSM/W)

NCT01376895
View directory record Official record
Conditions
Unsafe Sex, Risk Reduction
Interventions
PROJECT POWER, Power Health
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Jul 21, 2026, 11:07 AM EDT
Not listed Not applicable Interventional

Evaluating the Many Ways of Being Program

NCT05801601
View directory record Official record
Conditions
Sexual Behavior, Unprotected Sex
Interventions
Many Ways of Being, an innovative sexual health promotion program focused on addressing rigid gender norms and promoting healthy relationships, A career readiness program
Behavioral
Lead sponsor
Child Trends
Other
Eligibility
15 Years to 19 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Jul 21, 2026, 11:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)

NCT07475702
View directory record Official record
Conditions
Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
Interventions
Moon and Sun Brothers: A Community Prevention Intervention
Behavioral
Lead sponsor
San Francisco State University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
San Francisco, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protect and Connect: Couple HIV Prevention for Drug Involved Male Offenders

NCT01690494
View directory record Official record
Conditions
Sexually Transmitted Diseases, Unsafe Sex, Substance-Related Disorders
Interventions
PACT, TAU
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 17, 2018 · Synced Jul 21, 2026, 11:07 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication

NCT06878755
View directory record Official record
Conditions
Condomless Sex, Sexual Assault
Interventions
Promoting Assertive Communication among Teens (PACT), Healthy Minds
Other
Lead sponsor
North Carolina Agriculture & Technical State University
Other
Eligibility
14 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

FASTLANE II: Reducing Sex, Drug, and Mental Health Risk

NCT04109014
View directory record Official record
Conditions
Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
Interventions
FASTLANE II
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2022 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

MyLife MyStyle Evaluation Project

NCT01640392
View directory record Official record
Conditions
Unsafe Sex
Interventions
MyLife MyStyle group-level intervention
Behavioral
Lead sponsor
Los Angeles County Department of Public Health
Government
Eligibility
18 Years to 29 Years · Male only
Enrollment
528 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Jul 21, 2026, 11:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Copper T380A IUD vs. Oral Levonorgestrel for Emergency Contraception

NCT00966771
View directory record Official record
Conditions
Pregnancy
Interventions
Copper T380 IUD, Oral levonorgestrel
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
548 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Salt Lake City, Utah • West Valley City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Jul 21, 2026, 11:07 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Individual and Contextual Factors That Influence Sexual Decisions

NCT03224416
View directory record Official record
Conditions
Binge Drinking, Unsafe Sex, HIV/AIDS, Sexually Transmitted Diseases
Interventions
Alcohol Administration, Placebo Alcohol Administration, No Alcohol Administration
Other
Lead sponsor
Brown University
Other
Eligibility
21 Years to 35 Years · Male only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Jul 21, 2026, 11:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of the SafeSpace App Intervention

NCT06043596
View directory record Official record
Conditions
Health Behavior, Health Care Utilization, Unprotected Sex, Sexually Transmitted Infections
Interventions
SafeSpace Sexual Health, SafeSpace General Health
Behavioral
Lead sponsor
Child Trends
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Jul 21, 2026, 11:07 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

NC Young Women's CoOp

NCT02965014
View directory record Official record
Conditions
Condomless Sex, Human Immunodeficiency Virus (HIV), Sexually Transmitted Infection (STI), Alcohol and Drug Use
Interventions
Face-to-Face Young Women's CoOp (YWC), mHealth Young Women's CoOp (YWC), HIV Counseling and Testing
Behavioral
Lead sponsor
RTI International
Other
Eligibility
18 Years to 25 Years · Female only
Enrollment
652 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
4
States / cities
Durham, North Carolina • Greensboro, North Carolina • High Point, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Jul 21, 2026, 11:07 AM EDT
Completed Phase 1 Interventional

Telephone-delivered Behavioral Interventions to Reduce Risky Sexual Behavior in HIV-positive Late Middle-age and Older Adults

NCT01499706
View directory record Official record
Conditions
Unsafe Sex
Interventions
1-session of telephone-administered motivational interviewing, 4-session telephone-administered motivational interviewing
Behavioral
Lead sponsor
Ohio University College of Osteopathic Medicine
Other
Eligibility
45 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 25, 2011 · Synced Jul 21, 2026, 11:07 AM EDT
Not listed Not applicable Interventional

Telephone Counseling to Enhance the Quality and Safety of Romantic and Sexual Relationships in People Living and Aging With HIV

NCT03004170
View directory record Official record
Conditions
HIV Seropositivity
Interventions
Telephone-Administered Motivational Interviewing Plus Behavioral Skills Training, Telephone-Administered Coping Effectiveness Training
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
50 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Jul 21, 2026, 11:07 AM EDT