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Showing 1–24 of 80 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Upper Extremity Hemiparesis Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis

NCT00125658
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
Control, Experimental
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Feasibility of Action Observation and Repetitive Task Practice on Upper Extremity Outcomes in Chronic Stroke Survivors

NCT04015271
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Action Observation + Repetitive Task Practice, Placebo Video + Repetitive Task Practice
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Jun 10, 2026, 5:02 AM EDT
Terminated Phase 2 Interventional

Investigation of Neural Stem Cells in Ischemic Stroke

NCT03629275
View directory record Official record
Conditions
Ischemic Stroke, Chronic Stroke, Hemiparesis, Arm Paralysis
Interventions
CTX0E03 Drug Product and delivery device, Placebo
Combination Product · Drug
Lead sponsor
ReNeuron Limited
Industry
Eligibility
35 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
23
States / cities
Little Rock, Arkansas • Irvine, California • Los Angeles, California + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2021 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Translating Intensive Arm Rehabilitation in Stroke to a Telerehabilitation Format

NCT02665052
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Home-Based BATRAC plus TTT, Lab-based BATRAC plus TTT, Delayed Entry Usual Care
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 16, 2021 · Synced Jun 10, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional

Utility of CC7 Transfer in Stroke Subtypes

NCT06001736
View directory record Official record
Conditions
Stroke, Ischemic, Stroke Hemorrhagic, Spastic Hemiparesis
Interventions
Contralateral C7 root transfer for the treatment of spastic hemiparesis.
Procedure
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Bilateral Priming Plus Task Specific Training for Severe Upper Limb Hemiparesis

NCT03517657
View directory record Official record
Conditions
Stroke
Interventions
Bilateral Motor Priming + Task Specific Training (BMP + TST), Control Priming + TST (CP + TST)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Not listed Phase 2 Interventional

Constraint-Based Therapy to Improve Motor Function in Children With Cerebral Palsy

NCT00061139
View directory record Official record
Conditions
Cerebral Palsy, Motor Deficits
Interventions
Pediatric Constraint-Induced Movement therapy, Conventional pediatric motor rehabilitation therapy
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
2 Years to 6 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Feasibility of the Lee Silverman Voice Treatment®-BIG Intervention in Stroke

NCT03602443
View directory record Official record
Conditions
Chronic Stroke
Interventions
LSVT®BIG Intervention, Waitlist Control
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 23, 2020 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Phase 2 Interventional

Children With Hemiparesis Arm and Hand Movement Project (CHAMP Study)

NCT01895660
View directory record Official record
Conditions
Hemiparesis, Cerebral Palsy, Brain Injury
Interventions
Variations in Pediatric Constraint-Induced Movement Therapy (P-CIMT) versus usual and customary rehabilitation
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
2 Years to 9 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke

NCT00142792
View directory record Official record
Conditions
Stroke, Acute, Stroke, Hemiparesis
Interventions
NMES device with EMG-triggered and Cyclic capabilities
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
3
States / cities
Akron, Ohio • Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

Contralaterally Controlled FES of Arm & Hand for Subacute Stroke Rehabilitation

NCT01688856
View directory record Official record
Conditions
Stroke, Hemiparesis, Hemiplegia
Interventions
Electrical Stimulator
Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 80 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 8, 2020 · Synced Jun 10, 2026, 5:02 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

NCT04798378
View directory record Official record
Conditions
Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Interventions
Neurosleeve
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Recruiting Not applicable Interventional

Transcutaneous Electrical Stimulation for Stroke Patients

NCT06950593
View directory record Official record
Conditions
Upper Limb Hemiparesis Following Stroke
Interventions
Task Specific Training (TST), Transcutaneous electrical spinal cord stimulation (TESS), Sham transcutaneous electrical spinal cord stimulation (Sham TESS)
Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Implementing Outcome Measures in Stroke Rehabilitation

NCT04888416
View directory record Official record
Conditions
Stroke, Upper Extremity Dysfunction, Hemiplegia, Hemiparesis, Knowledge, Attitudes, Practice
Interventions
I-STROM
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
484 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 10, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Terminated Not applicable Interventional

Task or Virtual Reality Intervention for Improving UE Function

NCT03811275
View directory record Official record
Conditions
Upper Extremity Paresis, Hemiplegia and/or Hemiparesis Following Stroke, Hemiplegic Cerebral Palsy
Interventions
Virtual Reality (A) then Task (B), Task (B) then Virtual Reality (A)
Behavioral
Lead sponsor
Idaho State University
Other
Eligibility
18 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Pocatello, Idaho
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

TheraBracelet Phase I

NCT03318341
View directory record Official record
Conditions
Hand Function, Stroke, Upper Extremity, Hemiparesis, Cerebrovascular Accident, Stroke Rehabilitation
Interventions
Real Stimulation, Sham Stimulation
Device
Lead sponsor
TheraBracelet, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 6, 2019 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Phase 1Phase 2 Interventional

The Baby CHAMP Study (Children With Hemiparesis Arm and Movement Project)

NCT02346825
View directory record Official record
Conditions
Hemiparesis, Cerebral Palsy
Interventions
Neurorehabilitation therapy with cast, Neurorehabilitation therapy with splint, Neurorehabilitation bimanual
Behavioral
Lead sponsor
Virginia Polytechnic Institute and State University
Other
Eligibility
6 Months to 24 Months
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
3
States / cities
Columbus, Ohio • Charlottesville, Virginia • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Neuromotor Prosthetic to Treat Stroke-Related Paresis

NCT03913286
View directory record Official record
Conditions
Stroke, Complication, Stroke, Stroke Sequelae, Hemiparesis, Arm Paralysis
Interventions
Cortimo
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Motor Learning for Upper Limb Hemiparesis After Stroke

NCT05765474
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Practice Variable, No Practice Variable
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
40 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional

Study of the Recovery of Muscle Function in the Arm/Hand After a Stroke

NCT01422005
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
Simultaneous Bimanual training, Conventional Occupational Therapy
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 75 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Jun 10, 2026, 5:02 AM EDT
Withdrawn Phase 4 Interventional

Combining Robotic-Assisted Therapy and Pharmacotherapy in Post-Stroke Rehabilitation

NCT02346630
View directory record Official record
Conditions
Stroke
Interventions
Placebo, Levodopa / Carbidopa, Armeo
Drug · Device
Lead sponsor
Ross D. Zafonte, MD
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 26, 2021 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Results available

A Study to Evaluate Lower Extremity Sleeve and Pump Device to Treat Hemiparesis

NCT05535257
View directory record Official record
Conditions
Upper Extremity Weakness, Stroke
Interventions
Sequential Compression Device
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Saint Johns, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Jun 10, 2026, 5:02 AM EDT
Completed No phase listed Observational

A Study to Collect Participants Experience of Living With Adult Upper Limb (AUL) Spasticity and to Assess the Arm Activity Measure (ArmA)

NCT05546190
View directory record Official record
Conditions
Spastic Hemiparesis, Muscle Spasticity
Interventions
Not listed
Lead sponsor
Ipsen
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Downey, California • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jun 10, 2026, 5:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Brain Machine Interface Control of an Robotic Exoskeleton in Training Upper Extremity Functions in Stroke

NCT01948739
View directory record Official record
Conditions
Stroke, Hemiparesis
Interventions
MAHI EXO-II exoskeleton augmented with BMI system
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 28, 2021 · Synced Jun 10, 2026, 5:02 AM EDT