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ClinicalTrials.gov public records Last synced Oct 22, 2026, 6:10 PM EDT

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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Urethral Obstruction Clear all
Completed Not applicable Interventional

Effect of Caudal and Penile Block on Hypospadias Repair Complications

NCT02851290
View directory record Official record
Conditions
Hypospadias
Interventions
Caudal block anesthesia, Dorsal penile nerve block anesthesia
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
4 Months to 4 Years · Male only
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A Randomized Control Trial Comparing Single vs. Multiple Application of Lidocaine Analgesia Prior to Urethral Catheterization Procedures

NCT00142064
View directory record Official record
Conditions
Urinary Tract Infection, Kidney Diseases, Ureteral Diseases, Ureteral Obstruction
Interventions
observed levels of pain
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
2 Months to 7 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 18, 2007 · Synced Oct 22, 2026, 6:10 PM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Office Based Transperineal Laser Ablation for Benign Prostatic Hyperplasia HYPERPLASIA

NCT04760483
View directory record Official record
Conditions
Male Urogenital Diseases, Genital Diseases, Male, Prostatic Disease, Prostatic Hyperplasia
Interventions
SoracteLite(TM) TPLA for BPH
Device
Lead sponsor
Urological Research Network, LLC
Other
Eligibility
40 Years to 85 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Hialeah, Florida
Source: ClinicalTrials.gov public record
Updated Jan 26, 2023 · Synced Oct 22, 2026, 6:10 PM EDT
Completed No phase listed Observational

GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology

NCT05470751
View directory record Official record
Conditions
Bladder Outlet Obstruction, Multiple Sclerosis, Cauda Equina Syndrome, Enlarged Prostate With Lower Urinary Tract Symptoms, Parkinson Disease, Lower Urinary Tract Symptoms, Detrusor Underactivity, Spinal Cord Injuries
Interventions
Intermittent self-catheterisation
Device
Lead sponsor
ConvaTec Inc.
Industry
Eligibility
18 Years to 100 Years · Male only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
West Orange, New Jersey • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Phase 3 Interventional

Phase 3 Evaluation of Re-Injection of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH)

NCT01438775
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
NX-1207
Drug
Lead sponsor
Nymox Corporation
Industry
Eligibility
45 Years and older · Male only
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
28
States / cities
Huntsville, Alabama • Atherton, California • San Diego, California + 25 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2014 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Not applicable Interventional Results available

The Value of Multiple Urine Flow Rate Measurements in Male Benign Prostatic Hyperplasia (BPH) Subjects

NCT00710749
View directory record Official record
Conditions
Bladder Outlet Obstruction, Lower Urinary Tract Symptoms
Interventions
Disposable device, Digital device, Clinic flow measurement
Device
Lead sponsor
Wellspect HealthCare
Industry
Eligibility
45 Years to 85 Years · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Not applicable Interventional

Transluminal Flexible Endoscopic Procedure in Foregut and Urologic Surgery

NCT00484783
View directory record Official record
Conditions
Gastric Foreign Body, Nos, Disorder of Abdomen (Disorder), Foreign Body in Esophagus, Prostatic Diseases, Disease of Small Intestine
Interventions
Natural Orifice Transluminal Endoscopic Surgery (NOTES), Natural Orifice Translumenal Endoscopic Surgery (NOTES)
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Early Phase 1 Interventional Results available

ROBUST I Pilot Study, Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease

NCT03014726
View directory record Official record
Conditions
Stricture Urethra
Interventions
Urotronic Drug Coated Balloon (DCB)
Combination Product
Lead sponsor
Urotronic Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Brooklyn Park, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Phase 1 Interventional Results available

Two Devices for Reflex Voiding Following Spinal Cord Injury

NCT00662207
View directory record Official record
Conditions
Spinal Cord Injury, Urinary Incontinence
Interventions
Vibrator, Anal dilator
Device · Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 70 Years · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 5, 2014 · Synced Oct 22, 2026, 6:10 PM EDT
Recruiting Early Phase 1 Interventional

Concomitant Renal and Urinary Bladder Allograft Transplantation

NCT04626167
View directory record Official record
Conditions
Chronic Kidney Diseases, Bladder Dysfunction, Bladder Absence, Posterior Urethral Valve, Neurogenic Bladder, Bladder Exstrophy, Bladder Outlet Obstruction, Failure, Kidney, Transplant
Interventions
Concomitant Renal and Urinary Bladder Allograft Transplantation
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
1 Year to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Not applicable Interventional

Re-establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease

NCT03270384
View directory record Official record
Conditions
Urethral Stricture
Interventions
Urotronic Drug Coated Balloon (DCB)
Device
Lead sponsor
Urotronic Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
5
States / cities
Iowa City, Iowa • Hanover, Maryland • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 22, 2026, 6:10 PM EDT
Terminated Not applicable Interventional

Fetal Cystoscopy for Lower Urinary Tract Obstruction

NCT02446184
View directory record Official record
Conditions
Urethral Obstruction
Interventions
Fetal Cystoscopy, Fetal vesicoamniotic shunt
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
16 Weeks to 26 Weeks · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Oct 22, 2026, 6:10 PM EDT
Active, not recruiting Not applicable Interventional Results available

ROBUST III- Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease

NCT03499964
View directory record Official record
Conditions
Urethral Stricture
Interventions
Optilume Drug Coated Balloon (DCB), Control Treatment
Device
Lead sponsor
Urotronic Inc.
Industry
Eligibility
18 Years and older · Male only
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
21
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Daytona Beach, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 22, 2026, 6:10 PM EDT
Withdrawn Not applicable Interventional

A Study Comparing a Disposable Flexible Cystoscope With Reusable Scopes in Adult Patients.

NCT06422312
View directory record Official record
Conditions
Bladder Cancer, Bladder Stone, Bladder Outlet Obstruction, Renal Stone, Renal Disease
Interventions
Cystoscopy with RedPine flexible disposable cystoscope, Cystoscopy with standard of care flexible reusable scope
Device
Lead sponsor
Guangzhou Red Pine Medical Instrument Co., Ltd.
Industry
Eligibility
18 Years to 120 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Hersey, Pennsylvania • Dallas, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Phase 4 Interventional Results available

Efficacy of Opioid-limiting Pain Management Protocol in Men Undergoing Urethroplasty

NCT03859024
View directory record Official record
Conditions
Pain, Postoperative, Urethral Stricture
Interventions
Oxycodone, Acetaminophen, Gabapentin, celebrex, Bupivacaine, Ibuprofen 800 mg, Dexamethasone
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Male only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Phase 3 Interventional

Phase 3 Evaluation of Re-Injection of NX-1207 for the Treatment of Benign Prostatic Hyperplasia (BPH)(NX02-0022)

NCT01846793
View directory record Official record
Conditions
Benign Prostatic Hyperplasia, BPH, Lower Urinary Tract Symptoms (LUTS), LUTS
Interventions
NX-1207
Drug
Lead sponsor
Nymox Corporation
Industry
Eligibility
45 Years and older · Male only
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
17
States / cities
Laguna Beach, California • San Diego, California • Aventura, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2017 · Synced Oct 22, 2026, 6:10 PM EDT
Recruiting Not applicable Interventional

Fetal Cystoscopy for Severe Lower Urinary Tract Obstruction

NCT03281798
View directory record Official record
Conditions
Lower Urinary Tract Obstructive Syndrome, Lower Urinary Tract Obstruction, Congenital, Bladder Outlet Obstruction, Bladder Outflow Obstruction
Interventions
Fetoscopes, Fetal Cystoscopy
Device · Procedure
Lead sponsor
Rodrigo Ruano
Other
Eligibility
18 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
2
States / cities
Miami, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 22, 2026, 6:10 PM EDT
Recruiting No phase listed Observational

Standardized Prenatal Clinical Care for LUTO

NCT02315521
View directory record Official record
Conditions
Urethral Obstruction
Interventions
Fetal Intervention for LUTO
Procedure
Lead sponsor
Baylor College of Medicine
Other
Eligibility
11 Weeks to 2 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 22, 2026, 6:10 PM EDT
Not yet recruiting Phase 4 Interventional

REDUCER Trial (TXA in Urethroplasty)

NCT07501884
View directory record Official record
Conditions
Urethral Stricture, Urethral Diseases
Interventions
Tranexamic Acid, Urethroplasty
Drug · Procedure
Lead sponsor
Amjad Alwaal, MD, MSc, FRCSC, FACS
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Phase 3 Interventional

Memokath® 044TW Stent for Treatment of Urethral Stricture

NCT00270504
View directory record Official record
Conditions
Urethral Stricture
Interventions
Memokath stenting
Device
Lead sponsor
Pnn Medical DK
Industry
Eligibility
21 Years and older · Male only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2009
U.S. locations
7
States / cities
San Francisco, California • Jackson, Mississippi • Cleveland, Ohio + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2009 · Synced Oct 22, 2026, 6:10 PM EDT
Enrolling by invitation Not applicable Interventional

Optimal Duration of Foley Catheter After Bulbar Urethroplasty

NCT07220980
View directory record Official record
Conditions
Urethral Stricture, Bulbar
Interventions
Early catheter removal, Later catheter removal
Device
Lead sponsor
Jane Kurtzman
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Burlington, Massachusetts • Buffalo, New York • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 22, 2026, 6:10 PM EDT
Completed Phase 3 Interventional

Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty

NCT05300685
View directory record Official record
Conditions
Urethral Stricture, Male
Interventions
Standard Buccal Harvest, Basic buccal procedure + Long acting local, Basic buccal procedure + Buccal block
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
San Francisco, California • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 22, 2026, 6:10 PM EDT
Withdrawn Not applicable Interventional

Mobile Health Application to Improve Patient Satisfaction After Urethroplasty

NCT06384066
View directory record Official record
Conditions
Urethral Stricture
Interventions
GetWell Mobile Application, Standard of Care
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 22, 2026, 6:10 PM EDT
Terminated Phase 4 Interventional Results available

Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion

NCT03151746
View directory record Official record
Conditions
Anesthesia, Urethral Obstruction
Interventions
Placebo, Gabapentin
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Oct 22, 2026, 6:10 PM EDT