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Conditions: Pelvic Floor Disorders
Interventions: Flourish HEC, which contains BioNourish, Routine pelvic physical therapy; Device · Other
Lead sponsor: Vaginal Biome Science; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Bellaire, Texas

Conditions: HIV/AIDS, Menopause, Inflammation Vagina
Interventions: Tenofovir, Emtricitabine; Drug
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older · Female only
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Vulvodynia, Vestibulodynia, Vulvar Diseases, Vulvar Vestibulitis, Vulvar Pain
Interventions: BioNourish, a component of the Flourish HEC kit, Control - no intervention; Device · Other
Lead sponsor: Vaginal Biome Science; Other
Eligibility: 18 Years to 52 Years · Female only
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Virginia Beach, Virginia

Conditions: Breast Neoplasms
Interventions: Biospecimen Collection, Electronic Health Record Review, Questionnaire Administration; Procedure · Other
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Urinary Tract Infections, Vaginal Flora Imbalance
Interventions: BioNourish; Device
Lead sponsor: Vaginal Biome Science; Other
Eligibility: Up to 89 Years · Female only
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Preterm Birth
Interventions: Not listed
Lead sponsor: University of Pennsylvania; Other
Eligibility: 13 Years to 50 Years · Female only
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Atrophic Vaginitis, Menopause, Recurrent Urinary Tract Infections
Interventions: Conjugated equine estrogen topical cream, Apricot kernel oil; Drug
Lead sponsor: University of Louisville; Other
Eligibility: 18 Years and older · Female only
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Bacterial Vaginosis
Interventions: Flourish HEC Vaginal Care System; Device
Lead sponsor: Vaginal Biome Science; Other
Eligibility: 18 Years to 52 Years · Female only
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Human Microbiome, Metagenome, Contraception, Cytokine
Interventions: Not listed
Lead sponsor: University of Utah; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Graft Vs Host Disease, Vulvovaginal Signs and Symptoms
Interventions: Vulvovaginal Symptom Questionnaire, Vaginal Microbiome Evaluation; Other · Diagnostic Test
Lead sponsor: Case Comprehensive Cancer Center; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Vaginal Microbiome, Gut Microbiome, Gut Health
Interventions: Active, Placebo; Dietary Supplement
Lead sponsor: Ocean Spray Cranberries, Inc.; Industry
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Advanced Ovarian Carcinoma, Recurrent Ovarian Carcinoma, Stage II Ovarian Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8
Interventions: Biospecimen Collection, Placebo Administration, Probiotic, Questionnaire Administration; Procedure · Drug · Dietary Supplement + 1 more
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 161 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Allergic Diseases, Asthma
Interventions: Vaginal seeding, Placebo Seeding, Standard care, Post-seeding Care; Drug · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 2
States / cities: New York, New York

Conditions: Cesarean Delivery Affecting Newborn, Obesity, Childhood, Intestinal Microbiome, Microbiota, Host Microbial Interactions, Gastrointestinal Microbiome
Interventions: Vaginal Seeding, No Vaginal Seeding; Biological · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 0 Days to 50 Years
Enrollment: 600 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2029
U.S. locations: 1
States / cities: Falls Church, Virginia

Conditions: Sexually Transmitted Infection
Interventions: Not listed
Lead sponsor: Boston Medical Center; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 2
States / cities: Boston, Massachusetts • Providence, Rhode Island

Conditions: Neovaginal Microbiome
Interventions: Flourish Vaginal Care system; Device
Lead sponsor: Vaginal Biome Science; Other
Eligibility: 18 Years and older
Enrollment: 56 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: New Hope, Pennsylvania

Conditions: HIV -1 Infection
Interventions: Live Biotherapeutic Product L. jensenii 1153-1666, Placebo; Drug
Lead sponsor: Craig Cohen, MD, MPH; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: C-section, Vaginal Seeding, Respiratory, Microbiome
Interventions: Vaginal Seeding, Sterile Swab; Biological · Other
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Bacterial Vaginosis, Candidiasis, Urinary Tract Infections, Genitourinary Syndrome of Menopause, Lichen Sclerosus, Lichen Planus, Vulvodynia, Endometriosis, Ureaplasma Infections, Cancer, Desquamative Inflammatory Vaginitis
Interventions: Vaginal Swab Collection; Diagnostic Test
Lead sponsor: Vaginal Biome Science; Other
Eligibility: 18 Years to 89 Years · Female only
Enrollment: 3,250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 20
States / cities: Fullerton, California • Los Angeles, California • Pasadena, California + 16 more

Conditions: Vaginal Flora Imbalance
Interventions: IVF; Other
Lead sponsor: Freya Biosciences ApS; Industry
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 301 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Waltham, Massachusetts

Conditions: Menopausal Complaints, Vaginal Atrophy, Genitourinary Symptoms, HIV (Human Immunodeficiency Virus), Menopause Related Conditions, Vaginitis, Perimenopause
Interventions: Vaginal estradiol tablets, Vaginal moisturizer; Drug · Other
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 40 Years to 70 Years · Female only
Enrollment: 62 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Microbiome, Antibiotic-Induced VVC, Vaginal Candidiasis
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2019
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Vaginal Microbiome
Interventions: Not listed
Lead sponsor: Viome; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Bothell, Washington

Conditions: Gestational Diabetes Mellitus (GDM), Pregnancy
Interventions: Fermented Poi; Other
Lead sponsor: University of Hawaii; Other
Eligibility: 18 Years and older · Female only
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 3
States / cities: Honolulu, Hawaii • Waimanalo, Hawaii

Search by objective public record fields.

Effects of Flourish HEC Vaginal Care System on Birth-Related Pelvic Floor Disorders

Role of Exogenous and Endogenous Sex Hormones on Tenofovir and Emtricitabine Disposition in Female Genital Tract

Effects of Flourish HEC on Localized Provoked Vulvodynia

Evaluation of Vaginal Microbiome as a Biomarker for the Improvement of Vaginal Health in Women With Breast Cancer, ARISE Study

Vaginal Care System for Menopausal Women With Urinary Tract Infections

Motherhood and Microbiome

Vaginal and Urinary Microbiome Trial

Effect of Flourish HEC Vaginal Care System on BV Recurrence and the Vaginal Microbiome

Changes in Vaginal, Cervical and Uterine Microflora With Levonorgestrel Intrauterine Device Placement

Vulvovaginal Graft-versus-Host Disease: Diagnosis and Microbiome Evaluation

The Effect Cranberry-Based Products on the Female Microbiome

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

Vaginal Microbiome Exposure and Immune Responses in C-section Infants

Vaginal Microbiome Seeding and Health Outcomes in Cesarean-delivered Neonates.

Long-Acting Progestin Contraception and the Vaginal Microbiome

Flourish Vaginal Care System to Establish Neovaginal Microbiome

Safety Study of MucoCept-CVN

MOdification Of THe Early-Life Respiratory Microbiome Through Vaginal SEEDing

Vaginal Ecosystem and Network in the United States Study

Vaginal Microbiome and IVF Pregnancy Outcome

Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV

Study of Antibiotic-induced Vaginal Yeast Infections in Healthy Women

Longitudinal Analysis of the Vaginal Microbiome

Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk