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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Conditions
Leg Injuries
Interventions
Not listed
Lead sponsor
Mitchell Selhorst
Other
Eligibility
13 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Westerville, Ohio
Conditions
Pain
Interventions
4975, Placebo
Drug
Lead sponsor
Anesiva, Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
6
States / cities
Bakersfield, California • Owings Mills, Maryland • Austin, Texas + 3 more
Conditions
Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy, Clavicle Fracture
Interventions
Experimental Treatment, Sham Comparator
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Active, not recruiting Not applicable Interventional

LSTR in Chevron Osteotomy

NCT06486753
Conditions
Bunion
Interventions
Chevron osteotomy bunion surgery with lateral soft tissue release
Procedure
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Results available

NexGen TM Tibia Clinical Outcomes Study

NCT03272373
Conditions
Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Collagen Disorders and/or Avascular Necrosis of the Femoral Condyle, Post-traumatic Loss of Joint Configuration, Moderate Valgus, Varus, or Flexion Deformities
Interventions
NexGen TM Monoblock Tibia, NexGen TM Modular Tibia
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
7
States / cities
Torrance, California • Wheat Ridge, Colorado • Mooresville, Indiana + 4 more
Conditions
Bunionectomy, Hallux Valgus
Interventions
Bupivacaine liposome injectable suspension 266 mg, Bupivacaine HCl, Bupivacaine liposome injectable suspension 133 mg
Drug
Lead sponsor
Pacira Pharmaceuticals, Inc
Industry
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
7
States / cities
North Little Rock, Arkansas • Pasadena, California • Dayton, Ohio + 4 more
Conditions
Hallux Valgus
Interventions
conventional surgical technique - Chevron-type distal metatarsal osteotomy, minimally invasive surgical technique
Procedure
Lead sponsor
Henry DeGroot, M.D.
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Newton, Massachusetts
Terminated No phase listed Observational Accepts healthy volunteers

Measurement of Arch Motion After Bunion Surgery

NCT02074748
Conditions
Hallux Valgus, Instability of the Foot Arch
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Pain, Post-surgical
Interventions
valdecoxib, valdecoxib/placebo, placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
21
States / cities
Phoenix, Arizona • Tempe, Arizona • Anaheim, California + 10 more
Conditions
Pain, Hallux Valgus
Interventions
valdecoxib, valdecoxib/placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
89
States / cities
Chandler, Arizona • Glendale, Arizona • Mesa, Arizona + 50 more
Terminated Phase 2Phase 3 Interventional Results available

Effect of Topical CBD Cream for Degenerative Hallux Disorders

NCT04103814
Conditions
Hallux Valgus, Hallux Rigidus
Interventions
magnesium-cannabidiolic acid cream, Placebo cream
Drug
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 2 Interventional Results available

Dysport in Hallux Abducto Valgus (HAV) Phase IIa

NCT03569098
Conditions
Hallux Abducto Valgus
Interventions
Botulinum toxin type A, Placebo
Biological · Drug
Lead sponsor
Ipsen
Industry
Eligibility
18 Years and older
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
29
States / cities
Jonesboro, Arkansas • Little Rock, Arkansas • Castro Valley, California + 25 more
Conditions
Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
Interventions
Total Knee Arthroplasty
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
760 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2035
U.S. locations
16
States / cities
Parker, Colorado • Tampa, Florida • Atlanta, Georgia + 13 more
Conditions
Arthrodesis, Bunion, Hallux Valgus
Interventions
Intramedullary Nail
Device
Lead sponsor
Paragon 28
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Atlantis, Florida
Completed Not applicable Interventional Accepts healthy volunteers

An Analysis of Kinesio® Tape on Mitigation of Dynamic Knee Valgus

NCT04769063
Conditions
Knee Valgus
Interventions
Kinesio Tape
Other
Lead sponsor
North Dakota State University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Fargo, North Dakota
Conditions
Rotator Cuff Repair, Ankle Arthroplasty or Arthrodesis, Hallux Valgus (Bunion) Resection
Interventions
Peripheral Nerve Stimulation, Sham
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
Los Angeles, California • San Diego, California • Bethesda, Maryland + 2 more
Conditions
Elbow Injuries, Sprain Ulnar Collateral Ligament, Upper Extremity Injuries, Strain of Ulnar Collateral Ligament, Complete Tear Ulnar Collateral Ligament
Interventions
Strengthening program, Exercise program
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
175 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Hallux Valgus
Interventions
Single injection posterior tibial nerve block, Posterior tibial nerve catheter
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Arthrodesis, Bunion, Hallux Valgus
Interventions
Small Bone Intramedullary Nail
Device
Lead sponsor
Paragon 28
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
Santa Rosa, California • Fort Collins, Colorado • Atlantis, Florida
Enrolling by invitation No phase listed Observational

Persona SoluTion PPS Femur PMCF

NCT07286513
Conditions
Rhematoid Arthritis, Osteo Arthritis of the Knee, Traumatic Arthritis of Knee (Diagnosis), Polyarthritis, Collagen Disorders, Avascular Necrosis of Femoral Condyle, Valgus Deformity, Varus Deformity, Flexion Deformity of Knee
Interventions
Total knee arthroplasty
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2037
U.S. locations
4
States / cities
Denver, Colorado • Louisville, Kentucky • Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

ROSA Robot Used in Total Knee Replacement Post Market Study

NCT03969654
Conditions
Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities, Rheumatoid Arthritis
Interventions
PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
181 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
5
States / cities
Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more
Recruiting No phase listed Observational Accepts healthy volunteers

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

NCT04715139
Conditions
Hyperpronated Foot, Reconstruction Surgeries of the Foot, Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle, Fixation of Small Bone Fragments of the Foot/Ankle, Lisfranc Arthrodesis, Mono or Bi-cortical Osteotomies in the Forefoot, First Metatarsophalangeal Arthrodesis, Akin Osteotomy, Midfoot and Hindfoot Arthrodeses or Osteotomies, Fixation of Osteotomies for Hallux Valgus Treatment (Scarf and Chevron), Arthrodesis of the Metatarsocuneiform Joint to Reposition and Stabilize Metatarsus Primus Varus, Osteotomy Fixation of Hallux Valgus Repair (Such as Scarf and Chevron Etc.), Medial Ankle Stabilization, Tibiotalocalcaneal Arthrodesis
Interventions
Products listed in Group/Cohort Description
Device
Lead sponsor
Arthrex, Inc.
Industry
Eligibility
2 Years and older
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
5
States / cities
Sacramento, California • Chicago, Illinois • Nashville, Tennessee + 2 more
Active, not recruiting Not applicable Interventional

Cemented vs Cementless Persona Keel RCT

NCT05630053
Conditions
Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis, Polyarthritis, Avascular Necrosis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee
Interventions
Cementless Persona Knee System, Cemented Persona Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
7
States / cities
Westminster, Colorado • Chicago, Illinois • Baltimore, Maryland + 4 more
Conditions
Hallux Valgus
Interventions
Not listed
Lead sponsor
DePuy Synthes Products, Inc.
Industry
Eligibility
22 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Virginia Beach, Virginia