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ClinicalTrials.gov public records Last synced Oct 22, 2026, 7:10 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 503 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Validation Study Clear all
Recruiting No phase listed Observational

The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment

NCT07643896
View directory record Official record
Conditions
Pregnant Individuals, Aneuploidy, Down Syndrome (Trisomy 21), 22q11.2 Deletion Syndrome, Trisomy 13, Trisomy 18, Sex Chromosome Abnormalities
Interventions
Not listed
Lead sponsor
BillionToOne Inc.
Industry
Eligibility
Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
9
States / cities
Phoenix, Arizona • Riverside, California • West Covina, California + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 22, 2026, 7:10 PM EDT
Not yet recruiting No phase listed Observational

Observational Data Collection for Blood Hemoglobin Algorithm Validation in Pediatrics

NCT07706140
View directory record Official record
Conditions
Hemoglobin, Cerebral Oxygenation, Congenital Heart Disease
Interventions
Noninvasive hemoglobin monitoring
Device
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Days to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational

PSG Validation Study of Zensorium Biosensing Wearable Device

NCT04200495
View directory record Official record
Conditions
Sleep Wake Disorders, Healthy
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
68 participants
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Feb 4, 2021 · Synced Oct 22, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Validation Study Using a Time-lapse Morphometry MIRI Imaging Incubator

NCT02852356
View directory record Official record
Conditions
Fertility
Interventions
MIRI-TL Incubator
Device
Lead sponsor
Ovation Fertility
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated May 24, 2024 · Synced Oct 22, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Polso SpO2 Accuracy Validation Study

NCT03735329
View directory record Official record
Conditions
Hypoxia
Interventions
Diagnostic test of SPO2
Device
Lead sponsor
ChroniSense Medical Ltd.
Industry
Eligibility
18 Years to 50 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 22, 2026, 7:10 PM EDT
Active, not recruiting No phase listed Observational

Clinical Effectiveness Assessment of VeriStrat® Testing and Validation of Immunotherapy Tests in NSCLC Subjects

NCT03289780
View directory record Official record
Conditions
Non-Small Cell Lung Cancer
Interventions
Not listed
Lead sponsor
Biodesix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5,006 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
42
States / cities
Huntsville, Alabama • Tuscaloosa, Alabama • Fayetteville, Arkansas + 38 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

Respiratory Rate Validation Study

NCT05856422
View directory record Official record
Conditions
Measure Accuracy of Respiratory Rate
Interventions
Respiratory rate measure based on PPG
Device
Lead sponsor
Gabi SmartCare
Industry
Eligibility
1 Minute to 12 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Magnetic Resonance & Optical Spectroscopy Validation

NCT01827527
View directory record Official record
Conditions
Validation Studies, Magnetic Resonance Spectroscopy
Interventions
Not listed
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years to 89 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study

NCT04559763
View directory record Official record
Conditions
Hypoxia, Desaturation of Blood
Interventions
Non-Invasive Controlled Hypoxia, Introduction of Motion conditions: tapping or rubbing
Device · Other
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 50 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational

Intraoperative Brachytherapy for Central Nervous System Lesions: A Validation Study of a Radioactive Seed Loading Device

NCT03088579
View directory record Official record
Conditions
Central Nervous System Lesion
Interventions
GammaTile seed loader
Device
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
2
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational

Validation of SEARCH, a Novel Hierarchical Algorithm to Define Long-term Outcomes After Pulmonary Embolism

NCT05568927
View directory record Official record
Conditions
Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension
Interventions
SEARCH algorithm
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Fresno, California • Irvine, California • Los Angeles, California + 5 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Noninvasive Blood Pressure Validation Study

NCT07774169
View directory record Official record
Conditions
Blood Pressure Monitoring, Blood Pressure
Interventions
Chest Worn Blood Pressure Monitor
Device
Lead sponsor
Perin Health Devices
Industry
Eligibility
22 Years to 90 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Louisville, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 22, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Predictive Validity of Lumbopelvic Stress Tests to Determine Those Who Will Benefit From Lumbar Traction: A Pilot Study

NCT03127410
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar traction
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Internet-Based and Self-Reports in Assessing Diet and Physical Activity Within AARP

NCT03268577
View directory record Official record
Conditions
Healthy Subject
Interventions
Internet-Based Intervention, Monitoring Device, Questionnaire Administration
Other · Device
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
50 Years to 74 Years
Enrollment
1,130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 4, 2020 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-invasive Prenatal Diagnostic Validation Study

NCT01574781
View directory record Official record
Conditions
Chromosome 13 Aneuploidy, Chromosome 18 Aneuploidy, Chromosome 21 Aneuploidy, Sex Chromosome Aberrations, Other Microdeletions
Interventions
Blood draw, Cheek swab/Saliva Sampling
Procedure
Lead sponsor
Natera, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,781 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jul 2, 2013 · Synced Oct 22, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hydration Factor Study for the Stayhealthy BC3

NCT01209936
View directory record Official record
Conditions
Body Composition
Interventions
D2O
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 80 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Oct 22, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Smart Sleep In-home Validation Extension Study

NCT03665844
View directory record Official record
Conditions
Healthy, Sleep Deprivation, Insufficient Sleep Syndrome
Interventions
SmartSleep Boost On, SmartSleep Boost Off
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 50 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Lehigh Acres, Florida
Source: ClinicalTrials.gov public record
Updated Nov 16, 2018 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Kenota 1 CWS Method Comparison Validation Study

NCT05702671
View directory record Official record
Conditions
Allergy, Immunoglobulin E-Mediated Allergic Disorder
Interventions
Total Immunoglobulin E, Obtained From Fingerstick Sample
Diagnostic Test
Lead sponsor
Kenota Inc.
Industry
Eligibility
Up to 80 Years
Enrollment
411 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Saint Paul, Minnesota • Chapel Hill, North Carolina • Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 22, 2026, 7:10 PM EDT
Completed Not applicable Interventional

Validation of the Cervicothoracic Differentiation Test

NCT06287242
View directory record Official record
Conditions
Neck Pain
Interventions
spinal manipulation
Other
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 11, 2024 · Synced Oct 22, 2026, 7:10 PM EDT
Completed No phase listed Observational

A Prospective Validation Study of a Rapid Point-of-Care Breath Test for Breast Cancer

NCT02888366
View directory record Official record
Conditions
Breast Cancer
Interventions
Not listed
Lead sponsor
Menssana Research, Inc.
Industry
Eligibility
18 Years and older · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
4
States / cities
Los Angeles, California • Montclair, New Jersey • Newark, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2018 · Synced Oct 22, 2026, 7:10 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Verily Clinical Study Watch Analytical Validation Study

NCT05534477
View directory record Official record
Conditions
Healthy Population, Chronic Disease
Interventions
Verily Clinical Study Watch, Vivalink ECG Patch, Modus StepWatch 4
Device
Lead sponsor
Verily Life Sciences LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
South San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 11, 2025 · Synced Oct 22, 2026, 7:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

COSMED K5 Validation and Reliability Study

NCT05145192
View directory record Official record
Conditions
Cardiopulmonary, Exercise
Interventions
COSMED K5 CPET (Cardiopulmonary Exercise Test), ParvoMedics CPET
Device
Lead sponsor
Baylor Research Institute
Other
Eligibility
20 Years to 29 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 22, 2026, 7:10 PM EDT
Not yet recruiting Not applicable Interventional

SpO2 Infant and Pediatric Study

NCT07615738
View directory record Official record
Conditions
SpO2 (Peripheral Oxygen Saturation) Measurement Validation, SpO2
Interventions
SpO2 Sensor
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
29 Days to 12 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 22, 2026, 7:10 PM EDT