- Conditions
- Vaping, Nicotine Dependence
- Interventions
- Double Blind Varenicline, Double Blind Placebo, QuitVaping, This Is Quitting
- Drug · Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 16 Years to 25 Years
- Enrollment
- 261 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
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Showing 1–24
of 63
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Addiction Nicotine
- Interventions
- VapeAway filter system
- Device
- Lead sponsor
- VapeAway
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Cigarette Smoking
- Interventions
- E-cigarette Switching, Financial Incentives
- Behavioral
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 21 Years to 100 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Obesity, Smoking Cessation
- Interventions
- ENDS, CI, No ENDS, NI
- Other
- Lead sponsor
- Brown University
- Other
- Eligibility
- 21 Years to 99 Years
- Enrollment
- 39 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- E Cigarette Use
- Interventions
- adapted vaping cessation intervention
- Behavioral
- Lead sponsor
- Veterans Medical Research Foundation
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- San Diego, California
- Conditions
- Vaping, Smoking Cessation
- Interventions
- Virtual Reality Program, VR Program
- Behavioral
- Lead sponsor
- Boston University
- Other
- Eligibility
- 13 Years to 19 Years
- Enrollment
- 119 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Smoking Cessation
- Interventions
- Bupropion, Zonisamide, Placebo bupropion, Placebo zonisamide, E-cigarette
- Drug · Other
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Smoking Cessation
- Interventions
- Enhanced E-cigarette Coaching, Quitline treatment as usual
- Behavioral
- Lead sponsor
- Consumer Wellness Solutions
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Smoking Cessation
- Interventions
- Varenicline Tartrate, Placebo
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 2
- States / cities
- New Haven, Connecticut • Charleston, South Carolina
- Conditions
- Former Smoker, Non-Smoker
- Interventions
- D10-phenanthrene
- Other
- Lead sponsor
- University of Minnesota
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Minneapolis, Minnesota
- Conditions
- Tobacco Cessation
- Interventions
- This is Quitting, Assessment only Control
- Other
- Lead sponsor
- Truth Initiative
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 2,588 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Substance Withdrawal Syndrome
- Interventions
- Abstinence from e-cigarettes
- Behavioral
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 147 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Burlington, Vermont
- Conditions
- Smoking Cessation
- Interventions
- GENERIC, eTARGET
- Behavioral
- Lead sponsor
- H. Lee Moffitt Cancer Center and Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,896 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2019
- U.S. locations
- 1
- States / cities
- Tampa, Florida
- Conditions
- Tobacco Use Disorder, Nicotine Dependence
- Interventions
- Counseling, Contingency management, Text-based support
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 350 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2028
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- E-cigarette Use
- Interventions
- E-cigarette cessation text-messaging intervention, Standard care control using standard national resources
- Behavioral
- Lead sponsor
- Jovan Gwon, PhD, RN, FIAAN
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Nicotine Vaping
- Interventions
- Kick-Nic! mobile phone application, NCI Quit Vaping website
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 12 Years to 19 Years
- Enrollment
- 306 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Smoking Cessation
- Interventions
- E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm, Loss framing incentive arm, Control
- Behavioral
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 6,006 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2017
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Nicotine Dependence, Cigarettes
- Interventions
- AI-enhanced smartphone app, AI-enhanced smartphone app, but with delayed access
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 14 Years to 20 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Nicotine Dependence, Tobacco Use Disorder
- Interventions
- Varenicline Pill, Contingency management, Counseling
- Drug · Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 18 Years to 40 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2027
- U.S. locations
- 3
- States / cities
- Charleston, South Carolina • Lancaster, South Carolina • Pickens, South Carolina
- Conditions
- Dual Use of Cigarettes and E-cigarettes, Gestational Weight Gain, Birth-weight-for-gestational-age z Score
- Interventions
- Simultaneous cessation intervention, Stepwise cessation intervention, Behavior counseling only
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- E Cigarette Use, Cessation, Tobacco, Cessation, Nicotine
- Interventions
- Nicotine Replacement Therapies, Brief Behavioral Counseling
- Drug · Behavioral
- Lead sponsor
- West Virginia University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 2
- States / cities
- Greenville, North Carolina • Morgantown, West Virginia
- Conditions
- Smoking Cessation, Obesity and Obesity-related Medical Conditions
- Interventions
- Electronic Cigarettes (EC), Nicotine replacement therapy (NRT)
- Other
- Lead sponsor
- Brown University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- E-Cig Use
- Interventions
- Remote Contingency Management (CM) for nicotine abstinence, Control
- Behavioral · Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 13 Years to 20 Years
- Enrollment
- 108 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Vaping Cessation
- Interventions
- Pivot for Vape
- Behavioral
- Lead sponsor
- Pivot Health Technologies Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 73 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- San Carlos, California