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Showing 1–24 of 64 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Study of a Smartphone-Based Vaping Cessation Program

NCT05642598
Conditions
Vaping Cessation
Interventions
Pivot for Vape
Behavioral
Lead sponsor
Pivot Health Technologies Inc.
Industry
Eligibility
21 Years and older
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Carlos, California
Completed Not applicable Interventional Accepts healthy volunteers Results available

Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents

NCT04951193
Conditions
Depressive Symptoms, Depression, Adolescent Behavior
Interventions
Behavioral Activation Therapy app, Treatment as Usual
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years to 20 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Smoking Cessation, Obesity and Obesity-related Medical Conditions
Interventions
Electronic Cigarettes (EC), Nicotine replacement therapy (NRT)
Other
Lead sponsor
Brown University
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Research and Innovation to Stop E-cigarette/Vaping in Young Adults

NCT04974580
Conditions
Nicotine Dependence, E-Cig Use
Interventions
Nicotine patch, Phone Counseling, Digital Coaching
Drug · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 24 Years
Enrollment
508 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

BREATHE Free Curriculum

NCT06862050
Conditions
Smoking Cessation; Tobacco Dependence, E-Cig Use, Nicotine Dependence, Other Tobacco Product
Interventions
BREATHE Free Curriculum
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Augusta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Quit Nicotine: E-Cig Cessation Intervention

NCT04898075
Conditions
E-Cig Use
Interventions
Remote Contingency Management (CM) for nicotine abstinence, Control
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
13 Years to 20 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Vaping, E-Cig Use
Interventions
cytisinicline, Placebo, Behavioral support
Drug · Behavioral
Lead sponsor
Achieve Life Sciences
Industry
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
Lexington, Kentucky • Boston, Massachusetts • Rochester, New York + 2 more
Conditions
Nicotine Dependence
Interventions
Nicotine patch, ENDS, Placebo patch, Placebo ENDS
Drug · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Vaping Prevention and Vaping in Youth (Vapechat)

NCT06003439
Conditions
Vaping, Smoking Cessation
Interventions
Virtual Reality Program, VR Program
Behavioral
Lead sponsor
Boston University
Other
Eligibility
13 Years to 19 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Tobacco Use Cessation, Addiction
Interventions
Healthy Futures: Alternative-to-Suspension Curriculum
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 18 Years
Enrollment
2,540 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Withdrawn Not applicable Interventional Accepts healthy volunteers

Electronic Cigarettes or Nicotine Inhaler for Smoking Cessation

NCT02004171
Conditions
Tobacco Use Disorder
Interventions
electronic cigarette, nicotine inhaler
Other · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 60 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Trial for Harm Reduction With Incentives & Vaping E-cigarettes

NCT06111053
Conditions
Obesity, Smoking Cessation
Interventions
ENDS, CI, No ENDS, NI
Other
Lead sponsor
Brown University
Other
Eligibility
21 Years to 99 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Completed Not applicable Interventional Accepts healthy volunteers Results available

Text Message Quit Vaping Intervention for Young Adults

NCT04251273
Conditions
Tobacco Cessation
Interventions
This is Quitting, Assessment only Control
Other
Lead sponsor
Truth Initiative
Other
Eligibility
18 Years to 24 Years
Enrollment
2,588 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Addiction Nicotine
Interventions
VapeAway filter system
Device
Lead sponsor
VapeAway
Industry
Eligibility
21 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Vaping, Nicotine Dependence
Interventions
Varenicline, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 25 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Vaping Teens, Vaping Behaviors, Vaping Cessation, Tobacco Use Disorder
Interventions
E-cigarette Cessation Manual
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
14 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Miami, Florida
Conditions
Smoking Cessation, Vaping Cessation
Interventions
Cytisinicline
Drug
Lead sponsor
Achieve Life Sciences
Industry
Eligibility
18 Years and older
Enrollment
479 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
29
States / cities
Mobile, Alabama • Tempe, Arizona • Little Rock, Arkansas + 26 more
Not listed Not applicable Interventional Accepts healthy volunteers

Attentional Bias Modification Training for E-cigarette Users

NCT05112562
Conditions
E-cigarette Use, Tobacco Use Cessation
Interventions
Computerized attentional bias modification training, Placebo attention control training
Behavioral
Lead sponsor
University of Wisconsin, Milwaukee
Other
Eligibility
18 Years to 29 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Recruiting Not applicable Interventional Accepts healthy volunteers

Vaped Phenanthrene

NCT07134426
Conditions
Former Smoker, Non-Smoker
Interventions
D10-phenanthrene
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
E-cigarette Use, Vaping, Nicotine Dependence
Interventions
Varenicline 1mg BID, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
New Haven, Connecticut • Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Randomized Clinical Trial to Reduce Harm From Tobacco

NCT02328794
Conditions
Smoking Cessation
Interventions
E-cigarette free access, E-cigarette/NRT/Zyban/Chantix Choice, Outcome Incentive arm, Loss framing incentive arm, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 99 Years
Enrollment
6,006 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Behavior, Health Risk, Implementation Science, E Cigarette Use, Cessation, Smoking, Incentives, Engagement, Patient, Peer Support, Media Literacy
Interventions
Text-massaging suport, Financial incentive, Media literacy
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 29 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Recruiting Not applicable Interventional Accepts healthy volunteers

Social Media Support Groups for Adolescent Vaping Cessation

NCT07540780
Conditions
Vaping, Vaping Cessation, Nicotine Dependence
Interventions
Social Media Intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of a Decision Aid for E-Cigarettes in Primary Care

NCT03836573
Conditions
Smoking, Cigarette, Smoking Cessation
Interventions
Smoking Cessation iPad Decision Aid Tool
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Gainesville, Florida