- Conditions
- Smoking Cessation; Tobacco Dependence, E-Cig Use, Nicotine Dependence, Other Tobacco Product
- Interventions
- BREATHE Free Curriculum
- Behavioral
- Lead sponsor
- Augusta University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Augusta, Georgia
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 62
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Vaping, Nicotine Dependence
- Interventions
- Varenicline, Placebo
- Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 25 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Vaping, Vaping Teens, Nicotine Dependence
- Interventions
- QuitVaping, This is Quitting (TIQ)
- Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 14 Years to 18 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Smoking Cessation, Vaping Cessation
- Interventions
- Cytisinicline
- Drug
- Lead sponsor
- Achieve Life Sciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 479 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 29
- States / cities
- Mobile, Alabama • Tempe, Arizona • Little Rock, Arkansas + 26 more
- Conditions
- Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping, Vaping
- Interventions
- Smartphone app, Text Message, Survey Administration
- Behavioral · Other
- Lead sponsor
- Fred Hutchinson Cancer Center
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 61 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Nicotine Vaping
- Interventions
- Kick-Nic! mobile phone application, NCI Quit Vaping website
- Behavioral
- Lead sponsor
- Yale University
- Other
- Eligibility
- 13 Years to 19 Years
- Enrollment
- 306 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2029
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Implementation Science, Engagement, Patient, E Cigarette Use, Peer Support, Vaping Teens, Vaping Cessation, Parent Support
- Interventions
- Parents Helping Parents program
- Behavioral
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 15 Years to 18 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Vaping, E-Cig Use
- Interventions
- cytisinicline, Placebo, Behavioral support
- Drug · Behavioral
- Lead sponsor
- Achieve Life Sciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 5
- States / cities
- Lexington, Kentucky • Boston, Massachusetts • Rochester, New York + 2 more
- Conditions
- Vaping, Nicotine Dependence
- Interventions
- Double Blind Varenicline, Double Blind Placebo, QuitVaping, This Is Quitting
- Drug · Behavioral
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 16 Years to 25 Years
- Enrollment
- 261 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Nicotine Addiction, Smoking Cessation
- Interventions
- Nicotine polacrilex, STAM 1100mAh CE4 eGo Clearomizer
- Drug · Other
- Lead sponsor
- Creighton University
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Interventions
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling, brief advice, brochure
- Behavioral · Drug
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Vaping, Cessation, Tobacco
- Interventions
- This is Quitting, Assessment only control, Waitlist control
- Behavioral · Other
- Lead sponsor
- Truth Initiative
- Other
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 1,681 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Washington D.C., District of Columbia
- Conditions
- Dual Use of Cigarettes and E-cigarettes, Gestational Weight Gain, Birth-weight-for-gestational-age z Score
- Interventions
- Simultaneous cessation intervention, Stepwise cessation intervention, Behavior counseling only
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Nicotine Dependence, Cigarettes
- Interventions
- AI-enhanced smartphone app, AI-enhanced smartphone app, but with delayed access
- Behavioral
- Lead sponsor
- State University of New York at Buffalo
- Other
- Eligibility
- 14 Years to 20 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Nicotine Dependence
- Interventions
- Nicotine patch, ENDS, Placebo patch, Placebo ENDS
- Drug · Other
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 65 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Nicotine Dependence
- Interventions
- Not listed
- Lead sponsor
- National Institute on Drug Abuse (NIDA)
- NIH
- Eligibility
- 18 Years to 60 Years
- Enrollment
- 159 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- Started 2013
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Substance Withdrawal Syndrome
- Interventions
- Abstinence from e-cigarettes
- Behavioral
- Lead sponsor
- University of Vermont
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 147 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2018
- U.S. locations
- 2
- States / cities
- Baltimore, Maryland • Burlington, Vermont
- Conditions
- Behavior, Health Risk, Implementation Science, E Cigarette Use, Cessation, Smoking, Incentives, Engagement, Patient, Peer Support, Media Literacy
- Interventions
- Text-massaging suport, Financial incentive, Media literacy
- Behavioral
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 19 Years to 29 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 1
- States / cities
- Omaha, Nebraska
- Conditions
- E-cigarette Use
- Interventions
- E-cigarette cessation text-messaging intervention, Standard care control using standard national resources
- Behavioral
- Lead sponsor
- Jovan Gwon, PhD, RN, FIAAN
- Other
- Eligibility
- 18 Years to 24 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2026
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Tobacco Use Cessation, Tobacco Use, Electronic Cigarette Use
- Interventions
- UP2UTobacco
- Behavioral
- Lead sponsor
- University of Virginia
- Other
- Eligibility
- 14 Years to 15 Years
- Enrollment
- 597 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Charlottesville, Virginia
- Conditions
- Smoking Cessation
- Interventions
- Bupropion, Zonisamide, Placebo bupropion, Placebo zonisamide, E-cigarette
- Drug · Other
- Lead sponsor
- Rose Research Center, LLC
- Industry
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 180 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Raleigh, North Carolina
- Conditions
- Smoking Cessation
- Interventions
- Enhanced E-cigarette Coaching, Quitline treatment as usual
- Behavioral
- Lead sponsor
- Consumer Wellness Solutions
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Depressive Symptoms, Depression, Adolescent Behavior
- Interventions
- Behavioral Activation Therapy app, Treatment as Usual
- Behavioral
- Lead sponsor
- Medical University of South Carolina
- Other
- Eligibility
- 16 Years to 20 Years
- Enrollment
- 106 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2023
- U.S. locations
- 1
- States / cities
- Charleston, South Carolina
- Conditions
- Cervical Dysplasia
- Interventions
- Nicotine Replacement Therapy, Electronic Cigarettes
- Other · Device
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years to 65 Years · Female only
- Enrollment
- 31 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma