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Showing 1–24 of 57 matching trials from the live ClinicalTrials.gov search.
Conditions
Vaping, Adolescent Behavior, Communication Research
Interventions
Tailored
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
13 Years to 20 Years
Enrollment
1,155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents

NCT04951193
Conditions
Depressive Symptoms, Depression, Adolescent Behavior
Interventions
Behavioral Activation Therapy app, Treatment as Usual
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
16 Years to 20 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Charleston, South Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of E-Cigarette Prevention Messages on Adolescents

NCT05985538
Conditions
Vaping Behavior
Interventions
Vaping prevention text messages, Wellness behaviors text messages
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
13 Years to 20 Years
Enrollment
480 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

A Virtual Reality Vaping Prevention Intervention for Adolescents

NCT07362069
Conditions
Vaping
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
12 Years to 15 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
2
States / cities
New Haven, Connecticut • Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Pittsburgh and Rural Area High School Tobacco Prevention

NCT05081843
Conditions
Adolescent Behavior, Tobacco Use, E-Cig Use
Interventions
AD IT UP media literacy intervention, Usual health education curriculum
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
13 Years to 17 Years
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Vaping, E Cig Use, Prescription Drug Misuse
Interventions
School-based Hybrid Intervention to Prevent Vaping and Prescription Drug Misuse
Behavioral
Lead sponsor
Christopher Williams
Industry
Eligibility
7 Years to 11 Years
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
White Plains, New York
Conditions
E-cigarette Use, Substance Use
Interventions
ENDS Prevention Intervention (TBD)
Behavioral
Lead sponsor
University of Hawaii
Other
Eligibility
10 Years to 14 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Honolulu, Hawaii
Conditions
Vaping
Interventions
Vaping prevention video ads
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
13 Years to 20 Years
Enrollment
3,113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Vaping Prevention Advertisements

NCT04836455
Conditions
Vaping
Interventions
The FDA's The REal Cost vaping prevention ads - Health harms theme, The FDA's The Real Cost vaping prevention ads - Addiction theme, Neutral vaping ads
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
13 Years to 17 Years
Enrollment
1,565 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Vaping
Interventions
An image resembling a social media post
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 25 Years
Enrollment
2,829 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

A Virtual Reality Game to Prevent E-cigarette and Cannabis Vaping

NCT07413432
Conditions
Cannabis, Vaping, Emotion Regulation
Interventions
Virtual reality videogame intervention for vaping prevention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 15 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
New Haven, Connecticut
Conditions
Vaping, Nicotine Dependence
Interventions
Varenicline, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 25 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Nicotine and Cannabis Vape Labeling Experiment - Spring 2025

NCT06919276
Conditions
Vaping, Adolescent, Electronic Cigarette Use, Nicotine, Cannabis
Interventions
Vaping Device Labeling
Other
Lead sponsor
University of Southern California
Other
Eligibility
11 Years to 19 Years
Enrollment
3,048 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Perceptions of Tobacco Products
Interventions
Each intervention will be a picture of a social media post. The posts will vary (in a 3X2 factorial design) the type of flavor described and whether concealability is described.
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 17 Years
Enrollment
4,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Novel Smartphone Application for Helping Teens Stop Vaping, QuitQuest Vaping R01

NCT07739706
Conditions
Tobacco-Related Carcinoma
Interventions
Smartphone Application-based Intervention, Survey Administration, Interview
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
13 Years to 17 Years
Enrollment
1,072 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Seattle, Washington
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Villainous Vape: Advancing Vaping Prevention Among Adolescents Through a Comic Book

NCT07737080
Conditions
Vaping Behaviors
Interventions
Health Impacts of E-cigarettes, Mind Matters: The Body's Response to Nicotine, Tobacco, and Vaping, The Villainous Vape
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
12 Years to 17 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit

NCT05493982
Conditions
E-cigarette Use
Interventions
Stanford Vaping Prevention curriculum
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
10 Years to 20 Years
Enrollment
2,779 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Study of Vaping Use Among Adolescent and Young Adult Patients With Cancer

NCT07860801
Conditions
Cancer, Vaping
Interventions
Study assessments
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
15 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Not listed Not applicable Interventional Accepts healthy volunteers

Guiding Good Choices for Health

NCT04040153
Conditions
Adolescent Substance Use
Interventions
Guiding Good Choices
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
11 Years to 12 Years
Enrollment
3,636 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
3
States / cities
Oakland, California • Aurora, Colorado • Detroit, Michigan
Conditions
E-Cig Use
Interventions
ECIG own, ECIG Vuse
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
21 Years to 25 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Implementation Science, Engagement, Patient, E Cigarette Use, Peer Support, Vaping Teens, Vaping Cessation, Parent Support
Interventions
Parents Helping Parents program
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
15 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Conditions
Vaping
Interventions
Exposure to Influencer Age and Context Variations in E-Cigarette Marketing
Other
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 17 Years
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Los Angeles, California
Completed Not applicable Interventional Accepts healthy volunteers

Vaping Prevention and Vaping in Youth (Vapechat)

NCT06003439
Conditions
Vaping, Smoking Cessation
Interventions
Virtual Reality Program, VR Program
Behavioral
Lead sponsor
Boston University
Other
Eligibility
13 Years to 19 Years
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Boston, Massachusetts
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents

NCT07460622
Conditions
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
Interventions
Virtual Reality E-Cigarette Prevention Program
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 15 Years
Enrollment
1,251 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
New Haven, Connecticut