Independent directory Public ClinicalTrials.gov records United States
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Showing 793–816 of 927 matching trials from the live ClinicalTrials.gov search.
Conditions
Coronary Artery Disease, Heart Disease
Interventions
Perflutren Lipid Microsphere Injectable Suspension
Drug
Lead sponsor
Lantheus Medical Imaging
Industry
Eligibility
40 Years to 65 Years · Female only
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
3
States / cities
Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota
Conditions
Coronary Artery Disease, Atherosclerosis
Interventions
Computed Tomography (CT) Scan
Procedure
Lead sponsor
Borgess Research Institute
Other
Eligibility
35 Years to 55 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Kalamazoo, Michigan
Conditions
Coronary Heart Disease
Interventions
Dalcetrapib (RO4607381), Placebo
Drug
Lead sponsor
Hoffmann-La Roche
Industry
Eligibility
18 Years to 75 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
11
States / cities
Jacksonville, Florida • Royal Oak, Michigan • Minneapolis, Minnesota + 7 more
Completed Not applicable Interventional Accepts healthy volunteers

Myocardial Infarction Genes (MI-GENES) Study

NCT01936675
Conditions
Coronary Artery Disease, Myocardial Infarction, Genomic Risk Communication
Interventions
Genetic Risk Score
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
45 Years to 70 Years
Enrollment
216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Completed Not applicable Interventional

Vitamin C and Cardiovascular Risk

NCT00534014
Conditions
Atherosclerosis, Type 2 Diabetes
Interventions
Vitamin C
Dietary Supplement
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Albuquerque, New Mexico
Completed Not applicable Interventional Results available

Tailored Communication to Reduce Cardiovascular Risk

NCT01286311
Conditions
Hypercholesterolemia, Coronary Artery Disease, Dyslipidemia, Hypertension
Interventions
Direct-to-patient tailored cardiovascular risk message system
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
40 Years to 79 Years
Enrollment
464 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Coronary Artery Disease, Chest Pain, Coronary Atherosclerosis, Stress Testing
Interventions
Cardiac CT Angiography, Stress Imaging Test (Stress Myocardial Perfusion Study or Stress Echocardiogram)
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
18 Years to 70 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Accepts healthy volunteers

Giving a Low Carbohydrate Diet to Overcome Hypertension

NCT04230928
Conditions
Hypertension, African Americans, Diet, Carbohydrate-Restricted, Risk Reduction Behavior
Interventions
Very low carbohydrate diet, Standard DPP-GLB diet, Standard DPP-GLB program modules
Other · Behavioral
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 74 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Ischemic Stroke, Cognitive Impairment
Interventions
tDCS, sham tDCS, Cognitive Therapy
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Recruiting No phase listed Observational

Risk of Recurrent CeAD After Pregnancy

NCT06258109
Conditions
Cervical Artery Dissection, Pregnancy Complications
Interventions
Not listed
Lead sponsor
University Hospital, Basel, Switzerland
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Salt Lake City, Utah • Charlottesville, Virginia
Conditions
Acute Myocardial Infarction
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
75 Years and older
Enrollment
3,042 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
81
States / cities
Fort Smith, Arkansas • Los Alamitos, California • Sacramento, California + 70 more
Conditions
Multiple Myeloma (MM)
Interventions
teclistamab+daratumumab followed by talquetamab+daratumumab followed by duration treatment with daratumumab and lenalidomide extended/maintenance, melphalan (MEL)-based hematopietic stem cell transplantation (HSCT) followed by drug therapy
Drug · Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2032
U.S. locations
1
States / cities
Little Rock, Arkansas
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors

NCT00666250
Conditions
Hypertension, Dyslipidemia, Hyperglycemia
Interventions
Xocai Activ drink
Dietary Supplement
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 95 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Atherosclerosis, Cardiovascular Disease, Inflammation, Insulin Resistance, Noninsulin-dependent Diabetes Mellitus
Interventions
Salsalate, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 75 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Phoenix, Arizona
Terminated No phase listed Observational Accepts healthy volunteers Results available

Sickle Cell Trait and the Risk of Venous Thromboembolism

NCT01148940
Conditions
Thrombosis
Interventions
Not listed
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
The Bronx, New York
Conditions
Arrhythmia, Cardiovascular Diseases, Heart Failure, CVD
Interventions
Not listed
Lead sponsor
CardioDx
Industry
Eligibility
18 Years to 90 Years
Enrollment
1,564 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
8
States / cities
Anchorage, Alaska • Palo Alto, California • Minneapolis, Minnesota + 5 more
Completed Phase 2 Interventional Results available

Decitabine for High-Risk Sickle Cell Disease

NCT01375608
Conditions
Neutropenia, Sickle Cell Disease
Interventions
Decitabine
Drug
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Foot Ulcer, Diabetic
Interventions
Not listed
Lead sponsor
Temple University
Other
Eligibility
40 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers Results available

Heart Health 4 Moms Trial to Reduce CVD Risk After Preeclampsia

NCT02147626
Conditions
Cardiovascular Disease, Preeclampsia, Hypertension, Post-partum Weight Retention
Interventions
Web-based educational and motivational modules, Information and Screening Group
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Heart Failure, COPD, Myocardial Infarction, Coronary Artery Bypass Graft, Pneumonia, Total Knee Replacement, Total Hip Replacement, Stroke
Interventions
Not listed
Lead sponsor
AdventHealth
Other
Eligibility
21 Years and older
Enrollment
1,218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Hypercholesterolemia, Atherosclerotic Cardiovascular Disease
Interventions
bempedoic acid, placebo
Drug
Lead sponsor
Esperion Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
779 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Clearwater, Florida • Georgetown, Texas
Conditions
Carotid Artery Diseases
Interventions
Transcarotid Artery Revascularization (TCAR)
Procedure
Lead sponsor
Silk Road Medical
Industry
Eligibility
18 Years to 79 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
53
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Tucson, Arizona + 49 more
Conditions
Hypertension, Cardiovascular Diseases, Cardiovascular Risk Factors, Circadian Rhythms, Sleep
Interventions
At-home Polysomnography, Circadian Protocol, Rested Wakefulness Trial, Overnight Sleep Trial, Regularized Sleep Schedule
Other · Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
25 Years to 64 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Suspended Not applicable Interventional Accepts healthy volunteers

Preeclampsia: A Marker for Future Cardiovascular Risk in Women

NCT01519297
Conditions
Preeclampsia, Pregnancy Induced Hypertension
Interventions
Irbesartan
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 50 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts