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ClinicalTrials.gov public records Last synced Nov 5, 2026, 3:07 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 657 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Vascular System Injury Clear all

Conditions: Traumatic Brain Injury
Interventions: Not listed
Lead sponsor: National Institute of Neurological Disorders and Stroke (NINDS); NIH
Eligibility: 18 Years and older
Enrollment: 886 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Carotid Artery Injury, Vertebral Artery Injury
Interventions: heparin, aspirin and clopidogrel; Drug
Lead sponsor: C. Clay Cothren, MD; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Orthostatic Hypotension, Spinal Cord Injury
Interventions: L-NAME, Midodrine, Placebo; Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Surgical Wound
Interventions: Manual compression, Cardiva VASCADE™ Vascular Closure System; Other · Device
Lead sponsor: Cardiva Medical, Inc.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 20
States / cities: Fairhope, Alabama • Newark, Delaware • Melbourne, Florida + 17 more

Conditions: Disability Physical, Brain Injuries, Stroke, Spinal Cord Injuries, Multiple Sclerosis, Paralysis
Interventions: Using adaptive device.; Device
Lead sponsor: Madonna Rehabilitation Hospital; Other
Eligibility: 1 Year to 85 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Multiple Sclerosis, Stroke
Interventions: Movement to Music, Adapted Yoga; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 65 Years
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Spinal Cord Injury
Interventions: Midodrine, Placebo; Drug
Lead sponsor: James J. Peters Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 2
States / cities: West Orange, New Jersey • The Bronx, New York

Conditions: Dementia, Chronic Disease, Neoplasm Metastasis, Lung Neoplasms, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Lung Diseases, Interstitial, Peripheral Vascular Disease, Diabetes With End Organ Injury
Interventions: Survey-based Patient/Clinician Jumpstart, EHR-based Clinician Jumpstart; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 756 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2025
U.S. locations: 3
States / cities: Seattle, Washington

Conditions: Eye Diseases, Retinitis Pigmentosa, Diabetic Retinopathy, Macular Degeneration, Traumatic Optic Neuropathy, Optic Atrophy
Interventions: cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cell exosomes; Biological
Lead sponsor: The Foundation for Orthopaedics and Regenerative Medicine; Other
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 1
States / cities: Naples, Florida

Conditions: Injuries, Spinal Cord, CVA (Cerebrovascular Accident), Traumatic Brain Injury, MS (Multiple Sclerosis), Muscle Spasticity, Cerebral Palsy, Spastic
Interventions: Prometra II Programmable Pump - Flowonix Medical; Device
Lead sponsor: Culicchia Neurological Clinic; Other
Eligibility: 22 Years to 85 Years
Enrollment: 92 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: Marrero, Louisiana

Conditions: Diabetic Foot Ulcer (DFU), Chronic Foot Ulcers
Interventions: Allograft; Other
Lead sponsor: Tides Medical; Industry
Eligibility: 18 Years and older
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 9
States / cities: Fresno, California • Los Angeles, California • Vista, California + 5 more

Conditions: Stroke, Acute, TBI, Neuromuscular Diseases, Status Epilepticus, Coma, Cerebrovascular Disorders, Spinal Cord Injuries, Neurological Injury, Neurologic Injury
Interventions: Timing of placement; Other
Lead sponsor: University of Mississippi Medical Center; Other
Eligibility: 18 Years to 85 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Jackson, Mississippi

Conditions: Diabetic Foot Ulcers
Interventions: Not listed
Lead sponsor: HyperMed; Industry
Eligibility: 21 Years to 85 Years
Enrollment: 256 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 3
States / cities: Sylmar, California • Cleveland, Ohio • Philadelphia, Pennsylvania

Conditions: Complex Diabetic Foot Wounds
Interventions: Grafix®; Other
Lead sponsor: Osiris Therapeutics; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 4
States / cities: Phoenix, Arizona • Tucson, Arizona • Miami, Florida + 1 more

Conditions: Diabetic Foot Ulcer
Interventions: PEP (Purified Exosome Product) / TISSEEL; Biological
Lead sponsor: Rion Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Blue Ash, Ohio

Conditions: Wounds, Leg Ulcers, Pressure Ulcers, Diabetic Foot Ulcers
Interventions: AutoloGel System; Device
Lead sponsor: Cytomedix; Industry
Eligibility: 18 Years to 95 Years
Enrollment: 131 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2012
U.S. locations: 2
States / cities: Augusta, Georgia • El Paso, Texas

Conditions: Acute and Chronic Wounds, Pressure Ulcers, Trauma Wounds, Diabetic Foot Ulcers, Venous Stasis Ulcers
Interventions: SNaP Wound Care System; Device
Lead sponsor: 3M; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 2
States / cities: Daly City, California

Conditions: Stroke, Stroke, Acute, Brain Injury, Acute
Interventions: Umbilical Cord Blood, Placebo; Biological · Other
Lead sponsor: Joanne Kurtzberg, MD; Other
Eligibility: 18 Years to 90 Years
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 6
States / cities: Aurora, Colorado • Gainesville, Florida • Atlanta, Georgia + 3 more

Conditions: Hyponatremia, SIADH
Interventions: Tolvaptan; Drug
Lead sponsor: Polderman, Kees, H., MD, PhD; Individual
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 2
States / cities: Pittsburgh, Pennsylvania

Conditions: Traumatic Brain Injury
Interventions: Autologous HB-adMSCs, Normal Saline; Biological · Drug
Lead sponsor: Hope Biosciences LLC; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 51 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Houston, Texas • San Antonio, Texas

Conditions: Chronic Disease, Neoplasm Metastasis, Lung Neoplasm, Pulmonary Disease, Chronic Obstructive, Heart Failure, Congestive, Liver Cirrhosis, Kidney Failure, Chronic, Multiple Organ Failure, Health Care Quality, Access, and Evaluation, Intensive Care Units, Palliative Care, Health Services, Palliative Care, Patient Care, Lung Diseases, Cerebrovascular Disorders, Brain Injuries
Interventions: Facilitator-Based Intervention; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years and older
Enrollment: 977 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 3
States / cities: Seattle, Washington

Conditions: Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity, Healthy Controls
Interventions: Not listed
Lead sponsor: Kessler Foundation; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: West Orange, New Jersey

Conditions: Diabetic Foot Ulcer, Non-healing Wound, Non-Healing Ulcer of Skin, Venous Leg Ulcer, Venous Ulcer
Interventions: Debritom; Device
Lead sponsor: Stephanie Wu; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: North Chicago, Illinois

Conditions: Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Intracranial Hemorrhages
Interventions: Phenobarbital, Saline; Drug
Lead sponsor: NICHD Neonatal Research Network; Network
Eligibility: Female only
Enrollment: 610 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1993 – 1997
U.S. locations: 11
States / cities: Palo Alto, California • New Haven, Connecticut • Washington D.C., District of Columbia + 8 more

Search by objective public record fields.

Evaluation, Pathogenesis, and Outcome of Subjects With or Suspected Traumatic Brain Injury

Anticoagulation in Blunt Cerebrovascular Injuries

Safety and Efficacy of L-NAME and Midodrine to Increase MAP

RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)

Impact of Custom Assistive and Adaptive Technology in Rehabilitation

Lakeshore Examination of Activity and Disability Exercise Response Study

Blood Pressure, Cerebral Blood Flow and Cognition in Spinal Cord Injury

Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)

Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Exosomes for NAION

Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

Tracheostomy With Bedside Simultaneous Gastrostomy Vs Usual Care Tracheostomy And Delayed Gastrostomy Placement

Hyperspectral Imaging to Assess and Predict Diabetic Foot Ulcers

GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds

Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)

The AutoloGel™ Post-Market Surveillance (TAPS) Program

Clinical Evaluation of the SNaP Wound Care System

Study of Allogeneic Umbilical Cord Blood Infusion for Adults With Ischemic Stroke

Tolvaptan for Patients With Acute Neurological Injuries

Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury

Facilitating Communication Study

Validation of an Obstacle Course Used in Patients With Muscle Tightness

Debritom - Micro Water Jet Technology and Wound Healing

Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage