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ClinicalTrials.gov public records Last synced Sep 30, 2026, 7:42 PM EDT

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Showing 25–48 of 53 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Venous Ulcer Care Clear all
Completed Phase 2 Interventional

Subjects With Non-Healing Venous Leg Ulcers Treated With Standard Care Plus Cryopreserved Human Umbilical Cord (TTAX01)

NCT03818828
View directory record Official record
Conditions
Venous Leg Ulcer
Interventions
TTAX01, Profore Compression Therapy, Cadexomer Iodine dressing
Biological · Other
Lead sponsor
BioTissue Holdings, Inc
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
6
States / cities
Carlsbad, California • Sylmar, California • North Chicago, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Sep 30, 2026, 7:42 PM EDT
Recruiting Phase 4 Interventional

Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers

NCT07089602
View directory record Official record
Conditions
Diabetic Foot, DFU, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Ulcer Foot, Venous Leg Ulcer, Leg Ulcer, Leg Ulcers Venous, Ulcer
Interventions
Standard of Care DFU, Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU, Membrane Wrap-Hydro™ DFU, Standard of Care VLU, Tri-Membrane Wrap™ VLU, Membrane Wrap™ VLU, Membrane Wrap-Lite™ VLU, Membrane Wrap-Hydro™ VLU
Other
Lead sponsor
BioLab Holdings
Industry
Eligibility
18 Years and older
Enrollment
650 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philidelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 30, 2026, 7:42 PM EDT
Not listed Not applicable Interventional

The Omeza Protocol for Chronic Ulcers

NCT04198441
View directory record Official record
Conditions
Venous Leg Ulcer, Diabetic Foot Ulcer
Interventions
Wound dressing
Device
Lead sponsor
Omeza, LLC
Industry
Eligibility
21 Years to 80 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
4
States / cities
Jacksonville, Florida • Newark, New Jersey • Portland, Oregon + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2021 · Synced Sep 30, 2026, 7:42 PM EDT
Completed Not applicable Interventional Results available

SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic Wounds

NCT00951080
View directory record Official record
Conditions
Ulcers, Wounds
Interventions
Traditional NPWT System, SNaP Wound Care System
Device
Lead sponsor
3M
Industry
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
17
States / cities
Phoenix, Arizona • Tucson, Arizona • Castro Valley, California + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 30, 2026, 7:42 PM EDT
Recruiting Not applicable Interventional

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

NCT06939673
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs), Pressure Ulcers, Surgical Wound Dehiscence (SWD), Chronic Wounds, Undermined and Tunneling Wounds
Interventions
Acellular Porcine-Derived Wound Matrix
Device
Lead sponsor
Reprise Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Coconut Creek, Florida • Tamarac, Florida
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Sep 30, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Use of dHACM in the Treatment of Venous Leg Ulcers

NCT02011503
View directory record Official record
Conditions
Leg Ulcer
Interventions
Multi-layer compression therapy, Application of dHACM
Procedure · Other
Lead sponsor
MiMedx Group, Inc.
Industry
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
15
States / cities
Phoenix, Arizona • Carlsbad, California • Castro Valley, California + 12 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2018 · Synced Sep 30, 2026, 7:42 PM EDT
Not listed Phase 2 Interventional

Study of VF001-DP in Patients With Chronic Venous Leg Ulcers

NCT02973893
View directory record Official record
Conditions
Ulcer, Leg Ulcer, Varicose Ulcer, Pathologic Processes, Skin Ulcer, Skin Diseases, Vascular Diseases, Cardiovascular Diseases
Interventions
Placebo, VF001-DP LD, VF001-DP HD
Biological
Lead sponsor
Factor Therapeutics Ltd.
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
17
States / cities
Carlsbad, California • Fresno, California • Laguna Hills, California + 10 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2018 · Synced Sep 30, 2026, 7:42 PM EDT
Enrolling by invitation Not applicable Interventional

A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers

NCT06453187
View directory record Official record
Conditions
Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions
Urinary Bladder Matrix (UBM) sheet device for Venous Leg Ulcers, Urinary Bladder Matrix (UBM) sheet device for Diabetic Foot Ulcers, AmnioExcel Plus for Venous Leg Ulcers, AmnioExcel Plus for Diabetic Foot Ulcers, Standard of Care
Device · Procedure
Lead sponsor
Integra LifeSciences Corporation
Industry
Eligibility
18 Years to 80 Years
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
13
States / cities
Los Angeles, California • San Francisco, California • Vista, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 30, 2026, 7:42 PM EDT
Terminated Phase 1 Interventional

Study of Individualized Wound Prevention Instruction to Prevent Venous Ulcer Development

NCT00727701
View directory record Official record
Conditions
Varicose Ulcer
Interventions
Aftercare summary
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 26, 2015 · Synced Sep 30, 2026, 7:42 PM EDT
Withdrawn Not applicable Interventional

Managing Wounds With Allevyn Life in a Home Health Care Environment

NCT02776800
View directory record Official record
Conditions
Wounds and Injuries
Interventions
Allevyn Life, Foam dressing with an integrated adhesive border
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Tustin, California • Wichita, Kansas • McAllen, Texas
Source: ClinicalTrials.gov public record
Updated Feb 9, 2017 · Synced Sep 30, 2026, 7:42 PM EDT
Recruiting Phase 4 Interventional

A Multicenter, Prospective, Controlled Modified Multi-Platform Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers.

NCT07364630
View directory record Official record
Conditions
Diabetic Foot Ulcer, Foot Ulcer Chronic, DFU, Ulcer Foot, Venous Leg Ulcer (VLU), Venous Leg Ulcer, Venous Ulcer, Leg Ulcers, Ulcer
Interventions
Tri-Membrane Wrap™ DFU, Membrane Wrap™ DFU, Membrane Wrap-Lite™ DFU, Membrane Wrap-Hydro™ DFU, Tri-Membrane Wrap™ VLU, Membrane Wrap™ VLU, Membrane Wrap-Lite™ VLU, Membrane Wrap-Hydro™ VLU
Other
Lead sponsor
BioLab Holdings
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Philidelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 30, 2026, 7:42 PM EDT
Not listed Not applicable Interventional

Direct Application of Integra Bilayer Matrices on Bare Calvarium Without Preliminary Burring

NCT05311124
View directory record Official record
Conditions
Wound Care, Pressure Ulcer, Venous Ulcer, Surgical Wound, Trauma Wounds, Draining Wound
Interventions
Integra Dermal Regeneration template (IDRT)
Device
Lead sponsor
Joshua Choo
Other
Eligibility
55 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Sep 30, 2026, 7:42 PM EDT
Not listed Not applicable Interventional

Effectiveness of Aurix Therapy in Venous Leg Ulcers

NCT02352454
View directory record Official record
Conditions
Venous Leg Ulcers
Interventions
Aurix
Device
Lead sponsor
Nuo Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
23
States / cities
Arcadia, California • Montebello, California • Visalia, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2018 · Synced Sep 30, 2026, 7:42 PM EDT
Active, not recruiting No phase listed Observational

HEAL-4: Real-World Effectiveness of 4 Amniotic Allografts Adjunctive to Standard Care in DFU, VLU, and PU

NCT07223515
View directory record Official record
Conditions
Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs), Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions
Not listed
Lead sponsor
Dynamic Medical Services dba Acesso Biologics
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Novi, Michigan • Murfreesboro, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Sep 30, 2026, 7:42 PM EDT
Completed Phase 4 Interventional

Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers

NCT06562296
View directory record Official record
Conditions
Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions
Amnion-Intermediate-Chorion, Amnion-Chorion-Amnion, Standard of Care
Other · Procedure
Lead sponsor
Cellution Biologics
Industry
Eligibility
18 Years to 98 Years
Enrollment
292 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Jacksonville, Florida • Cincinnati, Ohio • Weslaco, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 30, 2026, 7:42 PM EDT
Withdrawn Phase 3 Interventional

SAVES-IBD: Safety & Efficacy of Aspirin vs. Standard of Care for VTE Prophylaxis After IBD Surgery

NCT05104229
View directory record Official record
Conditions
Crohn Disease, Ulcerative Colitis, Venous Thromboembolism
Interventions
Aspirin 81Mg Ec Tab, Standard of Care
Drug
Lead sponsor
Stefan Holubar MD MS FACS, FASCRS
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Sep 30, 2026, 7:42 PM EDT
Recruiting Phase 3 Interventional

Tissue Repair Gel in Venous Leg Ulcers in AU/US

NCT06707103
View directory record Official record
Conditions
Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer, Venous Stasis, Wound Heal, Wound, Venous Insufficiency of Leg, Non-healing Wound
Interventions
TR987 0.1% gel + Standard of Care, Standard of care
Drug · Other
Lead sponsor
TR Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Jacksonville, Florida • Clinton Twp, Michigan • Lake Success, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Sep 30, 2026, 7:42 PM EDT
Terminated Not applicable Interventional Results available

A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1

NCT04577183
View directory record Official record
Conditions
Diabetic Foot Ulcer, Pressure Ulcer, Venous Leg Ulcer, Trauma Injury, Skin Tear, Chronic Ulcer
Interventions
RD1 System
Device
Lead sponsor
RedDress Ltd.
Industry
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Butler, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Sep 30, 2026, 7:42 PM EDT
Completed Not applicable Interventional

Effect of Prontosan Wound Irrigation Solution on Venous Ulcers

NCT01048307
View directory record Official record
Conditions
Wound Care, Venous Ulcer Care, Wound Cleansing, Chronic Wound Care
Interventions
Prontosan wound irrigation solution
Device
Lead sponsor
Calvary Hospital, Bronx, NY
Other
Eligibility
18 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 17, 2010 · Synced Sep 30, 2026, 7:42 PM EDT
Recruiting Phase 4 Interventional

Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.

NCT06826339
View directory record Official record
Conditions
Venous Leg Ulcer, Venous Leg, Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Ulcer Foot, Leg Ulcer, Ulcer Venous, Ulcer
Interventions
ACApatch™, caregraFT™, Standard of Care
Other
Lead sponsor
Tiger Biosciences, LLC.
Industry
Eligibility
21 Years and older
Enrollment
340 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Sep 30, 2026, 7:42 PM EDT
Not yet recruiting Phase 2 Interventional

Clinical Study to Evaluate the Safety and the Efficacy of EscharEx Drug Product (EX-03 Formulation) and Its Placebo Compared to Collagenase, Non-surgical Standard of Care, in Patients With Venous Leg Ulcers

NCT06690177
View directory record Official record
Conditions
Venus Leg Ulcers
Interventions
EscharEx (EX-03), Placebo (Gel vehicle)
Drug
Lead sponsor
MediWound Ltd
Industry
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Sep 30, 2026, 7:42 PM EDT
Withdrawn Not applicable Interventional

Clinical Evaluation of the SNaP Wound Care System

NCT01113658
View directory record Official record
Conditions
Acute and Chronic Wounds, Pressure Ulcers, Trauma Wounds, Diabetic Foot Ulcers, Venous Stasis Ulcers
Interventions
SNaP Wound Care System
Device
Lead sponsor
3M
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Daly City, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 30, 2026, 7:42 PM EDT
Recruiting Phase 4 Interventional

Evaluating Intact Fish Skin Graft and Standard of Care Versus Standard of Care Alone in Nonhealing Venous Leg Ulcers

NCT06693570
View directory record Official record
Conditions
Venous Leg Ulcer (VLU), Venous Leg Ulcers, Venous Leg, Nonhealing Venous Leg Ulcer
Interventions
Intact Fish Skin Graft (IFSG) + Standard of Care, Standard of Care
Other
Lead sponsor
Kerecis Ltd.
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Monroeville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Sep 30, 2026, 7:42 PM EDT
Withdrawn Phase 4 Interventional

Effectiveness of Aurix Therapy in Venous Leg Ulcers

NCT02940587
View directory record Official record
Conditions
Venous Leg Ulcers
Interventions
Aurix
Device
Lead sponsor
Cytomedix
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Sep 30, 2026, 7:42 PM EDT