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Conditions: Venous Ulcer of Leg
Interventions: IVUS, Continued Compression Therapy/Stockings; Diagnostic Test · Other
Lead sponsor: Philips Clinical & Medical Affairs Global; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 8
States / cities: Darien, Connecticut • Winter Park, Florida • Chicago, Illinois + 5 more

Conditions: Venous Leg Ulcer (VLU)
Interventions: Amnion-Intermediate-Chorion, Standard of Care (SOC); Other · Procedure
Lead sponsor: Cellution Biologics; Industry
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Rocky Mount, North Carolina

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound, Non-Healed
Interventions: DETEC® pH; Diagnostic Test
Lead sponsor: Progenitec Inc.; Industry
Eligibility: 21 Years and older
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Lake Success, New York • Arlington, Texas

Conditions: Partial Thickness Wound, Pressure Ulcer, Venous Ulcer, Diabetic Ulcer, Surgical Wounds, Trauma Wounds, Draining Wounds, Chronic Vascular Ulcer
Interventions: PuraPly™ Antimicrobial Wound Matrix; Device
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years and older
Enrollment: 310 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 15
States / cities: Prescott Valley, Arizona • Jupiter, Florida • Miami, Florida + 12 more

Conditions: Venous Leg Ulcer
Interventions: Summus Laser, Summus Laser Sham; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2027
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Venous Stasis Ulcers
Interventions: Novel Dressing; Device
Lead sponsor: Hollister Incorporated; Industry
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 8
States / cities: Phoenix, Arizona • Miami, Florida • Elk Grove Village, Illinois + 4 more

Conditions: Venous Leg Ulcer, Venous Stasis Ulcer
Interventions: No HP802 Treatment, No HP802 Vehicle Treatment; Biological · Other
Lead sponsor: Healthpoint; Industry
Eligibility: 18 Years and older
Enrollment: 206 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 29
States / cities: Tucson, Arizona • Castro Valley, California • Encinitas, California + 26 more

Conditions: Wound Care, Venous Ulcer Care, Wound Cleansing, Chronic Wound Care
Interventions: Prontosan wound irrigation solution; Device
Lead sponsor: Calvary Hospital, Bronx, NY; Other
Eligibility: 18 Years to 95 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Diabetic Foot Ulcer (DFU), Venous Leg Ulcer, Wound; Foot
Interventions: IP1: BioLab Membrane Wrap Lite IP2: BioLab Tri-Membrane Wrap, IP2: BioLab Tri-Membrane Wrap; Other
Lead sponsor: Capsicure, LLC; Network
Eligibility: 18 Years and older
Enrollment: 165 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 7
States / cities: Oxnard, California • Coral Gables, Florida • Miami, Florida + 4 more

Conditions: Pressure Injury, Venous Ulcer, Necrotizing Soft Tissue Infection, Diabetic Ulcers, Draining Wound
Interventions: MicroMatrix® Flex, MicroMatrix® UBM Particulate, Cytal® Wound Matrix 2-Layer; Device
Lead sponsor: Integra LifeSciences Corporation; Industry
Eligibility: 22 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 3
States / cities: Aurora, Colorado • Washington D.C., District of Columbia • Lake Success, New York

Conditions: Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis, Skin Ulcer, Leg Ulcer, Pyoderma, Peripheral Arterial Disease, Lymphedema, Surgical Complication, Venous Leg Ulcers (VLUs), Calciphylaxis, Sickle Cell Ulcer, Pressure Ulcer (PU), Diabetic Foot Ulcers (DFUs), Pressure Injury, Arterial Ulcers, Soft Tissue Radionecrosis (STRN), Traumatic Wounds, Chronic Ulcer
Interventions: Usual care; Other
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 300,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2030
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Wound Heal
Interventions: Biatain Ag, Cutimed Siltec Sorbact; Device
Lead sponsor: Coloplast A/S; Industry
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 5
States / cities: Hollywood, Florida • North Port, Florida • Clinton Township, Michigan + 2 more

Conditions: Diabetic Foot Ulcer
Interventions: DermACELL, GraftJacket, Conventional Care Dressings; Other
Lead sponsor: LifeNet Health; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 202 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 12
States / cities: Montgomery, Alabama • Tucson, Arizona • Carlsbad, California + 8 more

Conditions: Venous Stasis Ulcer, Quality of Patient Care
Interventions: cellular and tissue based therapy, debridement, advanced wound therapy, Nutritional screening; Biological · Procedure · Dietary Supplement
Lead sponsor: U.S. Wound Registry; Other
Eligibility: Not listed
Enrollment: 10,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: The Woodlands, Texas

Conditions: Diabetic Foot Ulcer, Venous Leg Ulcer
Interventions: PelloGraft, SanoGraft; Other
Lead sponsor: Surgenex; Industry
Eligibility: 18 Years and older
Enrollment: 180 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 2
States / cities: Vista, California • Tulsa, Oklahoma

Conditions: Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers, Pressure Injuries, Traumatic Wounds and Injuries, Surgical Wounds
Interventions: Motion NPWT; Device
Lead sponsor: West Boca Center for Wound Healing; Other
Eligibility: Not listed
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Coconut Creek, Florida

Conditions: Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer, Venous Stasis, Wound Heal, Wound, Venous Insufficiency of Leg, Non-healing Wound
Interventions: TR987 0.1% gel + Standard of Care, Standard of care; Drug · Other
Lead sponsor: TR Therapeutics; Industry
Eligibility: 18 Years and older
Enrollment: 312 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 4
States / cities: Jacksonville, Florida • Clinton Twp, Michigan • Lake Success, New York + 1 more

Conditions: Wounds and Injuries
Interventions: Allevyn Life, Foam dressing with an integrated adhesive border; Device
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 65 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 3
States / cities: Tustin, California • Wichita, Kansas • McAllen, Texas

Conditions: Pressure Ulcer, Venous Ulcer, Diabetic Ulcer, Surgical Wound, Trauma Wound
Interventions: PuraPly™ Antimicrobial Wound Matrix; Device
Lead sponsor: Organogenesis; Industry
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Mineola, New York

Conditions: Chronic Venous Leg Ulcers
Interventions: EPA+DHA, placebo; Dietary Supplement · Other
Lead sponsor: Ohio State University; Other
Eligibility: 55 Years and older
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Venous Leg Ulcers
Interventions: Aurix; Device
Lead sponsor: Cytomedix; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Boise, Idaho

Conditions: Venous Leg Ulcer (VLU)
Interventions: Omeza OCM™ Wound Matrix, Routine Care; Device · Procedure
Lead sponsor: Omeza, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 254 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Lake Success, New York

Conditions: Venous Leg Ulcers
Interventions: HP802-247, Vehicle; Biological
Lead sponsor: Healthpoint; Industry
Eligibility: 18 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 37
States / cities: Phoenix, Arizona • Carlsbad, California • Castro Valley, California + 32 more

Conditions: Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU), Pressure Ulcer (PU)
Interventions: dHPT, AIC; Biological
Lead sponsor: Cellution Biologics; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Chicago, Illinois

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Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU)

Nonhealing Venous Leg Ulcers Treated With a Standard of Care (SoC) Alone or Standard of Care and Dehydrated Human Placenta Tissue (dHPT) With Crossover

DETEC® pH Point of Care Wound Diagnostic Test

The RESPOND Registry

Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy

Wound Fluid Protease Levels During Use of Novel Wound Dressing

Safety Follow-Up to HP 802-247-09-015

Effect of Prontosan Wound Irrigation Solution on Venous Ulcers

CAMP RWE Trial: Amnion Grafts for Healing Hard-to-Heal Ulcers in RW Populations

MicroMatrix® Flex in Tunneling Wounds

A Real-World Registry of Chronic Wounds and Ulcers

A RCT Evaluating the Clinical Benefit of a Silver Dressing in the Treatment of Venous Leg Ulcers

DermACELL in Subjects With Chronic Wounds of the Lower Extremities

Venous Leg Ulcer and Lymphedema Registry

Study Assessing Complete Wound Healing by Comparing Surgenex® PelloGraft in Treating DFU and SanoGraft® in Treating VLU to SOC

Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds

Tissue Repair Gel in Venous Leg Ulcers in AU/US

Managing Wounds With Allevyn Life in a Home Health Care Environment

PuraPly™ Antimicrobial Wound Matrix and Wound Management

Impact of Omega-3 Fatty Acid Oral Therapy on Healing of Chronic Venous Leg Ulcers in Older Adults

Effectiveness of Aurix Therapy in Venous Leg Ulcers

OCM™ Treatment With Routine Care in Venous Leg Ulcers Compared to Routine Care Treatment Alone.

Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers >12 cm2 to ≤ 36 cm2

Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing