- Conditions
- Critical Illness, Malnutrition, Gastrostomy, Procedural Sequelae, Trauma, Surgery, Mechanical Ventilation
- Interventions
- noFast: Start tube feeds within 1 hour of procedure
- Dietary Supplement
- Lead sponsor
- Carilion Clinic
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 1,200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Respiratory Failure
- Interventions
- Enteral Vitamin D3 50,000 IU, Enteral Vitamin D3 100,000IU, Inactive substance
- Drug · Other
- Lead sponsor
- Emory University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 31 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia
- Conditions
- Ventilator Associated Pneumonia
- Interventions
- Procalcitonin Level
- Device
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 29 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2014
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Deep Sedation, Ventilators, Mechanical, Critical Illness
- Interventions
- Midazolam, Propofol, Dexmedetomidine
- Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 7 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Hyperoxia, Normoxic, Delirium
- Interventions
- Normoxic oxygenation, Hyperoxic oxygenation
- Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 65 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2021
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Patients Who Are Mechanically Ventilated and Sedated
- Interventions
- sedation monitoring with RASS score, sedation monitoring with BIS-Guided monitoring
- Other
- Lead sponsor
- Englewood Hospital and Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 1
- States / cities
- Englewood, New Jersey
- Conditions
- Critical Illness, Sleep Deprivation, Respiratory Failure, Sleep Disorders, Circadian Rhythm
- Interventions
- Sleep and circadian rhythm promotion, Usual care
- Behavioral
- Lead sponsor
- Brian Gehlbach
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2016
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Iowa City, Iowa
- Conditions
- Neuromodulation, Phrenic Nerve Stimulation, Ventilator Induced Diaphragm Dysfunction, Mechanical Ventilation Weaning
- Interventions
- pdSTIM System Therapy, Conventional Medical Management
- Device · Other
- Lead sponsor
- Stimdia Medical Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2025
- U.S. locations
- 21
- States / cities
- Mobile, Alabama • Chandler, Arizona • Goodyear, Arizona + 18 more
- Conditions
- Mechanical Ventilation, Airway Patency, Respiratory Depression
- Interventions
- Subanesthetic ketamine
- Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2022
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts
- Conditions
- Respiratory Syncytial Virus Infections
- Interventions
- Live Music Therapy, Recorded Music Therapy
- Behavioral
- Lead sponsor
- Children's Healthcare of Atlanta
- Other
- Eligibility
- Up to 2 Years
- Enrollment
- 33 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Sepsis, Respiratory Failure, Agitation
- Interventions
- Propofol, Dexmedetomidine, Fentanyl
- Drug
- Lead sponsor
- Texas Tech University Health Sciences Center
- Other
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 36 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Lubbock, Texas
- Conditions
- Pulmonary Disease
- Interventions
- Leak-free bronchoscope adapter
- Device
- Lead sponsor
- Endeavor Health
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Pulmonary Edemas, Blood Protein Disorders
- Interventions
- RBC transfusion of 5 days or less storage age, RBC transfusion of conventional storage age
- Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Cardiac Physiology, Cardiac Output
- Interventions
- NICO device
- Device
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2010
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Pneumonia
- Interventions
- Amikacin inhalation solution (BAY41-6551)
- Drug
- Lead sponsor
- Bayer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007
- U.S. locations
- 4
- States / cities
- Birminghan, Alabama • Cincinnati, Ohio • Memphis, Tennessee + 1 more
- Conditions
- Multidisciplinary Communication
- Interventions
- Nurse-led progressive mobility protocol, Standard of Care
- Other
- Lead sponsor
- University of Texas Southwestern Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 28 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Respiratory Failure, Dyspnea During Mechanical Ventilation, Mechanical Ventilation
- Interventions
- Change to VC/AC, Change in Tidal Volume, Change in inspiratory flow, Change in PEEP, Change to PSV
- Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Otitis Media
- Interventions
- Intranasal fentanyl, morphine IM, IV morphine
- Drug
- Lead sponsor
- Baylor College of Medicine
- Other
- Eligibility
- 6 Months to 6 Years
- Enrollment
- 171 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Agitation
- Interventions
- acupuncture, sham acupuncture
- Device
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 6 Months to 17 Years
- Enrollment
- 17 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Acute Respiratory Failure
- Interventions
- Not listed
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 28 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Effect of Protocolized Sedation on Days of Mechanical Ventilation in the ICU
- Interventions
- Sedation protocol
- Other
- Lead sponsor
- Tampa General Hospital
- Other
- Eligibility
- 18 Years to 100 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Riverview, Florida
- Conditions
- Intensive Care Unit Syndrome, Mechanical Ventilation Complication, Sedatives and Hypnotics Causing Adverse Effects in Therapeutic Use, Delirium
- Interventions
- Not listed
- Lead sponsor
- Interfaith Medical Center
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 124 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Sedation
- Interventions
- Isoflurane, Propofol, Isoflurane (run-ins)
- Drug
- Lead sponsor
- Sedana Medical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 277 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 14
- States / cities
- Aurora, Colorado • Atlanta, Georgia • Chicago, Illinois + 9 more
- Conditions
- Nonverbal Communication, Critical Illness
- Interventions
- Aim 1 - VidaTalk - post-extubation, Aim 2 - VidaTalk - intubated, Aim 3 - VidaTalk tablet app, Aim 3 - attention-control with non-VidaTalk tablet
- Other · Device
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 147 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Columbus, Ohio