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ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:31 PM EDT

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Showing 1–24 of 3,048 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Ventilation Clear all
Completed No phase listed Observational Results available

Autologous Stem Cell Treatment for Chronic Lung Disease Study

NCT03044431
View directory record Official record
Conditions
COPD, Interstitial Lung Disease
Interventions
Cell therapy
Procedure
Lead sponsor
Lung Institute
Industry
Eligibility
16 Years and older
Enrollment
207 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2018 · Synced Oct 17, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Physiological Effects of Acute and Ramp Simulated Altitude Exposure During Simulated Flight Tasks

NCT05867719
View directory record Official record
Conditions
Altitude Hypoxia
Interventions
Hypoxic breathing conditions
Other
Lead sponsor
University of Texas, El Paso
Other
Eligibility
18 Years to 40 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 17, 2026, 6:31 PM EDT
Completed Not applicable Interventional Results available

Long QT Syndrome and Sleep Apnea

NCT03678311
View directory record Official record
Conditions
Long QT Syndrome, Sleep Apnea
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 2, 2020 · Synced Oct 17, 2026, 6:31 PM EDT
Completed Not applicable Interventional Results available

Metabolic Study of Sleep Apnea in Men and Women

NCT00706511
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
CPAP
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Oct 17, 2026, 6:31 PM EDT
Withdrawn Not applicable Interventional

A Strategy to Improve Implementation of LTVV for Patients w/ ARDS

NCT03051139
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome
Interventions
Multi-component LTVV implementation strategy
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 6, 2020 · Synced Oct 17, 2026, 6:31 PM EDT
Recruiting Not applicable Interventional

NPA-OSA Device Tolerability, Usability and Acclimation Clinical Study in Adult Obstructive Sleep Apnea (OSA) Patients

NCT06677151
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
nasopharyngeal airway obstructive sleep apnea (NPA-OSA) device
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 17, 2026, 6:31 PM EDT
Terminated Not applicable Interventional

Noninvasive Estimation of Work of Breathing

NCT02867228
View directory record Official record
Conditions
Acute Respiratory Distress Syndrome
Interventions
changes in ventilator settings
Other
Lead sponsor
Respironics, California, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2017 · Synced Oct 17, 2026, 6:31 PM EDT
Not listed Not applicable Interventional

Efficacy of Oxepa Enteral Feeding in LTAC (Long Term Acute Care Hospital) Patients on Chronic Ventilation- a Pilot Study

NCT02208700
View directory record Official record
Conditions
Acute Lung Injury, Mechanical Ventilation Complication, Dietary Modification
Interventions
Oxepa, Jevity 1.5
Other
Lead sponsor
Grace Hospital, Cleveland, Ohio
Other
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 5, 2014 · Synced Oct 17, 2026, 6:31 PM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Comparison of Esophageal Manometry and CT Scan Measurements

NCT04213911
View directory record Official record
Conditions
Morbid Obesity, Respiratory Failure
Interventions
low-dose chest CT scan, insertion of esophageal balloon
Radiation · Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 17, 2026, 6:31 PM EDT
Recruiting Not applicable Interventional

Type 1 Diabetes and Obstructive Sleep Apnea

NCT06915831
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Type 1 Diabetes (T1D)
Interventions
Continuous positive airway pressure (CPAP)
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 17, 2026, 6:31 PM EDT
Terminated No phase listed Observational

Muscle Atrophy in Patients With Severe Sepsis

NCT01717651
View directory record Official record
Conditions
Severe Sepsis, Respiratory Failure
Interventions
Not listed
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 18, 2016 · Synced Oct 17, 2026, 6:31 PM EDT
Terminated Phase 2 Interventional Results available

Treprostinil Sodium Inhalation for Patients At High Risk for ARDS

NCT02370095
View directory record Official record
Conditions
Respiratory Distress Syndrome, Adult
Interventions
Treprostinil Inhalation Solution, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Oct 17, 2026, 6:31 PM EDT
Completed No phase listed Observational

Actigraphy to MEasuRe Intensive Care Unit Activity

NCT02263716
View directory record Official record
Conditions
Disability, Physical Activity, Aging, Critical Illness
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 6, 2017 · Synced Oct 17, 2026, 6:31 PM EDT
Completed Not applicable Interventional Results available

Initiation of CPAP for Newly Diagnosed OSA in Hospitalized Heart Failure Patients

NCT03056443
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Heart Failure
Interventions
Continuous Positive Airway Pressure (CPAP)
Device
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2022 · Synced Oct 17, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does myTAP Oral Appliance Therapy Including a Mouth Shield Lessen Periodontitis in Mouth-Breathers Who Snore?

NCT06797089
View directory record Official record
Conditions
Snoring, Mouth Breathing, Daytime Sleepiness, Periodontitis
Interventions
Oral appliance therapy plus scaling and root planing on left or right of mouth
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 85 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Oct 17, 2026, 6:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Super-Oxygenated Water on Blood Oxygen Saturation

NCT07016191
View directory record Official record
Conditions
Adult Subject
Interventions
Ingestion of Water
Other
Lead sponsor
Inhale, Inc
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Westlake Village, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 17, 2026, 6:31 PM EDT
Completed Not applicable Interventional

Evaluating Artificial Intelligence-Based Clinical Decision Support for Sepsis and ARDS

NCT07025096
View directory record Official record
Conditions
Sepsis, Acute Respiratory Distress Syndrome (ARDS)
Interventions
Artifical Intelligence-Generated Treatment Recommendations
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 23, 2026 · Synced Oct 17, 2026, 6:31 PM EDT
Completed Phase 2Phase 3 Interventional

Enabling Sleep Apnea Patient-Centered Care Via an Internet Intervention

NCT00662623
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
i-PAP, Usual Care (Standard Care)
Behavioral
Lead sponsor
Veterans Medical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 13, 2016 · Synced Oct 17, 2026, 6:31 PM EDT
Enrolling by invitation Not applicable Interventional

Long-term Evaluation of Nasopharyngeal Airway in Hypotonia

NCT06614582
View directory record Official record
Conditions
Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
Interventions
Self-Supporting Nasopharyngeal Airway (ssNPA)
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 23 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 17, 2026, 6:31 PM EDT
Withdrawn Phase 3 Interventional

Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF

NCT04592380
View directory record Official record
Conditions
Dyspnea, Hypertension, Acute Heart Failure
Interventions
Stage 1: Clevidipine (double-blinded), Stage 1: Placebo (double-blinded), Stage 2: Clevidipine (open-label), Stage 2: Standard of Care (open-label)
Drug
Lead sponsor
The Medicines Company
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
9
States / cities
Montgomery, Alabama • Tucson, Arizona • St Louis, Missouri + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 17, 2026, 6:31 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Maternal Hyperoxygenation for Intrapartum Fetal Heart Rate Tracing Abnormalities

NCT03996317
View directory record Official record
Conditions
Perinatal Death, Respiratory Distress Syndrome, Newborn, Hypoxic-Ischemic Encephalopathy, Neonatal Seizure, Meconium Aspiration Syndrome, Intracranial Hemorrhages, Neonatal Hypotension
Interventions
Room air
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 55 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 17, 2026, 6:31 PM EDT
Not listed Not applicable Interventional

The Advance Trial. Tongue Advancement for Obstructive Sleep Apnea: An Evaluation of the Aspire Medical Advance System

NCT00467324
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Aspire Medical Advance System
Device
Lead sponsor
Aspire Medical
Industry
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
4
States / cities
Atlanta, Georgia • Indianapolis, Indiana • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2008 · Synced Oct 17, 2026, 6:31 PM EDT
Not yet recruiting Not applicable Interventional

C-LIFT Efficacy in Patients With Obstructive Sleep Apnea

NCT07807124
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
C-Lift
Device
Lead sponsor
Ata Murat Kaynar
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 17, 2026, 6:31 PM EDT
Terminated Phase 1 Interventional Results available

Study of the Safety of Therapeutic Tx With Immunomodulatory MSC in Adults With COVID-19 Infection Requiring Mechanical Ventilation

NCT04397796
View directory record Official record
Conditions
COVID
Interventions
BM-Allo.MSC, Placebo
Biological
Lead sponsor
ImmunityBio, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Lynwood, California
Source: ClinicalTrials.gov public record
Updated Sep 5, 2024 · Synced Oct 17, 2026, 6:31 PM EDT