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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ventricular Function Clear all
Completed Phase 1Phase 2 Interventional

A Phase I - II Safety Study of Filgrastim (Neupogen) to Improve Left Ventricular Function After Severe Acute Myocardial Infarction

NCT00215124
View directory record Official record
Conditions
Acute Myocardial Infarction
Interventions
Filgrastim
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2007
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2008 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Relationship Between the Response to Mental Stress and Vascular Endothelial Function

NCT00975559
View directory record Official record
Conditions
Coronary Endothelial Dysfunction, Apical Ballooning Syndrome, Myocardial Infarction
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2011
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 25, 2012 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional Results available

Effects of Nebivolol on Exercise Tolerance and Left Ventricular Systolic and Diastolic Function

NCT01056718
View directory record Official record
Conditions
Hypertension
Interventions
Nebivolol
Drug
Lead sponsor
Mercy Research
Other
Eligibility
18 Years to 90 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

The Determination of Important Mechanical Patterns of Left Ventricular Efficiency-MV02 Study

NCT01807819
View directory record Official record
Conditions
Heart Failure
Interventions
Heart Failure
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Sep 6, 2026, 1:59 PM EDT
Terminated Phase 1 Interventional

Stem Cell Injection to Treat Heart Damage During Open Heart Surgery

NCT01557543
View directory record Official record
Conditions
Heart Disease, Ischemic Heart Disease, Coronary Artery Disease, Coronary Artery Disease (CAD)
Interventions
Cell Therapy
Other
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional

"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"

NCT01317329
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Hypoxia, Hypercapnia, Sleep Disorders, Obesity, Hypertension, Coronary Artery Vasospasm, Right Ventricular Overload, Left Ventricular Function Systolic Dysfunction, Ventricular Hypertrophy
Interventions
Clinically prescribed CPAP therapy
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 5, 2020 · Synced Sep 6, 2026, 1:59 PM EDT
Withdrawn Not applicable Interventional

Effects of Pentoxiphylline on Left Ventricular (LV) Systolic Function Indices and Circulating Biomarkers in Patients With Chronic Congestive Heart Failure (CHF)

NCT01337349
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
Placebo, Pentoxifylline
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Sep 6, 2026, 1:59 PM EDT
Terminated No phase listed Observational

Examining Developmental Changes in Heart Contractions of Children With Congenital Heart Defects

NCT00860327
View directory record Official record
Conditions
Hypoplastic Left Heart Syndrome, Tetralogy of Fallot
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
1 Day to 1 Year
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 21, 2016 · Synced Sep 6, 2026, 1:59 PM EDT
Recruiting Not applicable Interventional

Impact of Early Fortini Initiation on Growth and Interstage Outcomes in Infants With Single Ventricle Physiology

NCT07087782
View directory record Official record
Conditions
Single-ventricle
Interventions
Fortini formula, Standard Nutritional Care
Other
Lead sponsor
Driscoll Children's Hospital
Other
Eligibility
0 Months to 6 Months
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Corpus Christi, Texas
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

Validation of the Gated Blood Pool SPECT: ERNA vs 3D Echo

NCT00576186
View directory record Official record
Conditions
Congestive Heart Failure, Ventricular Function, Left
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 22, 2016 · Synced Sep 6, 2026, 1:59 PM EDT
Enrolling by invitation No phase listed Observational

Federated Learning for Point-of-Care Cardiac Ultrasound

NCT07800962
View directory record Official record
Conditions
Ventricular Dysfunction, Left, Ventricular Function, Left, Echocardiography, Ultrasonography, Point-of-Care Systems, Heart Function Tests, Stroke Volume, Federated Learning, Machine Learning, Artificial Intelligence (AI), Deep Learning, Neural Networks, Computer, Image Interpretation, Computer-Assisted, Diagnosis, Computer-Assisted, Sensitivity and Specificity, ROC Curve
Interventions
Focused Cardiac Point-of-Care Ultrasonography, FL-POCUS Federated Machine-Learning Analysis System
Diagnostic Test · Device
Lead sponsor
Truway Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2037
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Recruiting Not applicable Interventional

Feasibility of the SCD in Cardiorenal Syndrome Patients Awaiting LVAD

NCT03836482
View directory record Official record
Conditions
Acute on Chronic Systolic Congestive Heart Failure, Cardiorenal Syndrome
Interventions
Selective Cytopheretic Device
Device
Lead sponsor
SeaStar Medical
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

Validating TEE Measurements of Right Ventricular Function

NCT03264183
View directory record Official record
Conditions
Ventricular Function, Right, Echocardiography, Transesophageal
Interventions
Transesophageal Echocardiography, Transthoracic Echocardiography
Diagnostic Test
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2019 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional

Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology

NCT02860702
View directory record Official record
Conditions
Congenital Heart Defect
Interventions
Human Milk Derived Fortifier, Human/Bovine Milk
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
1 Day to 7 Days
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
12
States / cities
Loma Linda, California • Los Angeles, California • Orange, California + 9 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Phase 4 Interventional Results available

Targeting the Right Ventricle in Pulmonary Hypertension

NCT01839110
View directory record Official record
Conditions
Pulmonary Hypertension
Interventions
Ranolazine, Placebo
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Baltimore, Maryland • Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional Results available

Hemodynamic Comparison of Tissue Aortic Valves

NCT01635244
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Aortic valve replacement
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 2, 2017 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional Results available

BIO monitorinG in Patients With Preserved Left ventricUlar Function AfteR Diagnosed Myocardial Infarction

NCT02341534
View directory record Official record
Conditions
Myocardial Infarction, Myocardial Infarction, Acute, Myocardial Infarction Old
Interventions
BioMonitor
Device
Lead sponsor
Biotronik SE & Co. KG
Industry
Eligibility
18 Years to 99 Years
Enrollment
802 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
8
States / cities
St Louis, Missouri • Rochester, New York • Grand Forks, North Dakota + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fat Metabolism in Pregnancy and Neonatal Heart Function in Diabetes

NCT01346527
View directory record Official record
Conditions
Type 2 Diabetes, Pregnancy
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 10, 2018 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

Left Ventricular Torsional Hysteresis: A Global Parameter for Diastolic Function

NCT01431027
View directory record Official record
Conditions
Heart Failure, Diastolic Heart Failure, Heart Failure With Normal Ejection Fraction
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 17, 2015 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Not applicable Interventional

Positive Therapy for Autonomic Function & Mood in ICD Patients

NCT02088619
View directory record Official record
Conditions
Ventricular Arrhythmia, Implantable Cardioverter Defibrillator
Interventions
Quality of Life Therapy (QOLT), Heart Healthy Education (HHE)
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 1, 2017 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating a New Echocardiography Imaging Procedure for Evaluating Heart Function

NCT00661323
View directory record Official record
Conditions
Ischemia, Myocardial Infarction, Ischemic Heart Disease
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 29, 2020 · Synced Sep 6, 2026, 1:59 PM EDT
Active, not recruiting Not applicable Interventional

REsynchronization Comparison In LBBB and Normal or Mildly Reduced VENTricular Function With CRT (REINVENT-CRT)

NCT05652218
View directory record Official record
Conditions
Left Ventricular Ejection Fraction, Heart Failure (HF), Left Bundle-Branch Block
Interventions
LB-CRT, BIV-CRT
Device
Lead sponsor
Inova Health Care Services
Other
Eligibility
Not listed
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Durham, North Carolina • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 6, 2026, 1:59 PM EDT
Completed Phase 3 Interventional

Safety and Efficacy Study of Carvedilol to Treat Children With Congestive Heart Failure

NCT00052026
View directory record Official record
Conditions
Congestive Heart Failure
Interventions
carvedilol, placebo
Drug
Lead sponsor
Shaddy, Robert, M.D.
Individual
Eligibility
1 Day to 17 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
21
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 16 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2008 · Synced Sep 6, 2026, 1:59 PM EDT
Completed No phase listed Observational

Speckle-tracking Tricuspid Annular Plane Systolic Excursion

NCT01968252
View directory record Official record
Conditions
Ventricular Function, Right
Interventions
Concurrent TTE and TEE
Other
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years to 90 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Sep 6, 2026, 1:59 PM EDT